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Short-Term Study Body Weights

Study Information:

Chemical Name: Milk thistle extract
CASRN: ="84604-20-6"
Study Number: C20008
Exposure Route: DOSED FEED
TDMS Number: 2000801
Sex: Male
Strain and Species: F 344/N Rats

Table Instructions and Notes:
Multiple body weights in a single week are displayed in one cell separated by "|". Values displayed may not match report summary values due to individual values being excluded in some cases.
Animal Number Cage Number Dose Group Days On Study Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 Week 13 Week 14 Removal Reason
1 1 Untreated Control 93 103.2 140.1 177.5 203 194.4 234.1 254.9 269.4 282.4 292.8 305.5 318.4 324.4 330.9 Terminal Sacrifice
2 1 Untreated Control 93 88.6 129.1 163.6 192.4 193.4 229.5 252 266 285.3 296.4 306 316.9 322.7 333.4 Terminal Sacrifice
3 1 Untreated Control 93 86 121.5 161.1 196 196.4 240 261.6 273.1 289.8 300 314.4 326.7 334.4 345.6 Terminal Sacrifice
4 1 Untreated Control 93 92.6 129.8 164.3 193.1 181.4 230.2 254.4 264.8 278.2 288.2 302.6 307.7 316 328.6 Terminal Sacrifice
5 1 Untreated Control 93 96.5 140.8 178.7 214.5 203.9 261.8 288.1 305 326.8 339.5 353.1 363.5 370.6 384.1 Terminal Sacrifice
6 2 Untreated Control 93 94.9 132.2 167.5 195.8 212.5 241.6 258.9 270.3 283.8 290 299.9 305.9 310.2 318.1 Terminal Sacrifice
7 2 Untreated Control 93 87.1 127.3 166.1 204.2 232.5 252.4 272.6 288.3 303.4 316.1 327.5 338.7 348.5 357 Terminal Sacrifice
8 2 Untreated Control 93 94.6 134.4 169.9 203.8 237.6 259.5 282.9 298.6 316.8 325.7 336.6 345.4 349.3 358.5 Terminal Sacrifice
9 2 Untreated Control 93 86.1 120.7 154.6 182.6 214 232.1 252.5 264.5 282.6 289.8 301.9 311.4 316.9 329.2 Terminal Sacrifice
10 2 Untreated Control 93 102.8 144.8 185.5 223.6 259.4 282.1 308.6 324.3 342.9 353.1 369.6 378.7 380.1 388.8 Terminal Sacrifice
11 3 3125PPM 93 89.5 130.9 169.3 203.7 234.4 252.6 267.2 285.7 303.8 317.4 325.7 339.1 343.9 353.9 Terminal Sacrifice
12 3 3125PPM 93 100.9 137.5 169.1 194 223.5 246 261 281.6 298.3 311.8 321.5 334.6 338.4 348.7 Terminal Sacrifice
13 3 3125PPM 93 87.8 126.9 158.4 188.7 218 234.2 248.9 266.1 281.1 294.2 303.4 310.4 317.5 331.1 Terminal Sacrifice
14 3 3125PPM 93 93.3 134.6 174.7 208.5 238.3 258.5 274.3 288.9 308.3 319.4 327.7 336.8 340.5 350.1 Terminal Sacrifice
15 3 3125PPM 93 89.8 129.4 162.3 200.1 229.6 246 261.5 278.9 294.4 305 314.1 326.7 330.7 338 Terminal Sacrifice
16 4 3125PPM 93 87 126.5 161 196.9 183.1 241.1 264.3 275.8 292.4 300 310.6 321 325.9 334.8 Terminal Sacrifice
17 4 3125PPM 93 90.9 128.8 163.6 193.2 185.1 242.9 261.4 279.4 293.4 303.3 317 326.8 334.8 345.7 Terminal Sacrifice
18 4 3125PPM 93 100.7 134.1 170 199.4 185.9 241.8 260.2 274.6 289.8 299.1 308.3 321 331.1 338.9 Terminal Sacrifice
19 4 3125PPM 93 89.3 131 171.9 206.1 194.1 250.5 275.3 291.2 311.5 318.4 330.9 345.1 352 360.5 Terminal Sacrifice
20 4 3125PPM 93 91.4 128.2 161.7 192.3 180.3 237.2 261 274.9 293.5 302.8 317.1 323.6 328 337.6 Terminal Sacrifice
21 5 6250PPM 93 91.2 122.7 157.1 186.1 217.2 233.9 251.1 264.7 280.7 290.6 300.3 310.1 319.3 325.9 Terminal Sacrifice
22 5 6250PPM 93 84.8 121.6 157.4 186 218.9 238 259.6 276.6 293.8 302.3 315.2 321 325.7 337.4 Terminal Sacrifice
23 5 6250PPM 93 87.2 131.7 167.3 206.1 244.1 260.1 280 300.7 319 332.6 344.5 353.5 364.5 370.4 Terminal Sacrifice
24 5 6250PPM 93 97.2 131.4 163.5 191.1 209.6 226.4 246.8 260.8 280.1 290.8 297.9 312.1 317.2 328 Terminal Sacrifice
25 5 6250PPM 93 87.7 127.5 165 200.8 237 260.2 277.9 295.8 310.5 322.1 332.5 344.8 354.5 369 Terminal Sacrifice
26 6 6250PPM 93 94.3 130.6 165 195.7 180.1 242.3 267.7 284 300 311.8 322.6 329.1 331.6 337.5 Terminal Sacrifice
27 6 6250PPM 93 100.9 135.1 169 203.9 195.3 254.4 283.7 295.8 314.5 324.5 341.4 352.8 357.3 370.2 Terminal Sacrifice
28 6 6250PPM 93 90.7 125.7 162.4 193.6 184.3 245 268.9 285.4 306.1 318.8 329.8 340.1 343 353.2 Terminal Sacrifice
29 6 6250PPM 93 85.7 122.8 156.5 191.6 181.3 240.8 266.3 284.3 301.4 314.2 323.4 335.1 340.7 356.8 Terminal Sacrifice
30 6 6250PPM 93 88 124.6 158.4 188.9 176 232.2 254 268.1 289 299.6 310.4 320.2 324.2 333.6 Terminal Sacrifice
31 7 12500PPM 93 102.2 140 174.4 205.5 233.7 251.8 266 284.8 300.8 309.1 315.9 326.6 326.8 330.5 Terminal Sacrifice
32 7 12500PPM 93 105.2 143.4 176.5 206 233.5 249.7 263.6 279.5 293 300.7 309.2 320.9 327.1 333.3 Terminal Sacrifice
33 7 12500PPM 93 98.1 123.2 152 172.5 199.7 219 230.6 248.9 264.8 276.3 286.3 294 305 310 Terminal Sacrifice
34 7 12500PPM 93 74.7 109.2 140.4 173.6 207.9 227.4 247.4 263.1 278.4 286.5 296.8 308.7 312 324.6 Terminal Sacrifice
35 7 12500PPM 93 84.8 115.1 152.7 180.2 213.4 233.3 251.2 268.3 284.7 298.4 308.5 314.2 321.9 333 Terminal Sacrifice
36 8 12500PPM 93 92.3 130 166.8 197.8 230.7 255.7 276.4 293.7 310.7 318.7 327.8 338.7 344.3 350.5 Terminal Sacrifice
37 8 12500PPM 93 88.5 127.9 160.6 192.9 219.2 238.2 256.5 272.4 284.3 295 303.7 313.3 327.1 336.9 Terminal Sacrifice
38 8 12500PPM 93 91.3 128.4 163.5 196.2 230.5 252.4 275.6 292 305 316.7 327.6 338.8 344.2 353.4 Terminal Sacrifice
39 8 12500PPM 93 83.7 115.8 146.8 177.1 209.9 229.2 244.2 263.1 275.2 289.1 297.6 307.5 316.3 321.3 Terminal Sacrifice
40 8 12500PPM 93 101.4 137.9 177.8 207.1 236.8 263.4 281.7 301.4 318.4 333.4 342 355.7 367.9 375.8 Terminal Sacrifice
41 9 25000PPM 93 91.5 123.8 157.6 188.8 225.2 243.5 262.5 281.5 296 304.3 308.3 311.7 318.4 322.6 Terminal Sacrifice
42 9 25000PPM 93 84.3 107.8 134.3 155 179.2 194.9 207.1 220.1 229.2 236.7 245.4 257.1 265.8 274.9 Terminal Sacrifice
43 9 25000PPM 93 86 120.1 155.7 185.6 218.3 240.1 258 274.1 287 297.3 307.7 313 324 334.2 Terminal Sacrifice
44 9 25000PPM 93 91.2 125.4 163.4 193.4 224.1 242.6 255.9 274.3 285.1 293.4 302.8 310.9 314.7 322.1 Terminal Sacrifice
45 9 25000PPM 93 94.9 123.2 155.8 175.6 200.5 210.9 222.3 232.8 243.8 249.4 258.7 264.6 267.9 270.9 Terminal Sacrifice
46 10 25000PPM 93 93 127.3 160.4 183.8 220.2 236.6 252.5 268.7 286.3 299.9 311.6 321.1 325.1 335.4 Terminal Sacrifice
47 10 25000PPM 93 88.8 119.3 148.8 168.5 203.5 222.2 241.2 255.5 273.4 286.3 294.4 307.3 315.6 325.9 Terminal Sacrifice
48 10 25000PPM 93 87.9 124.8 159.7 180 218.3 241.9 257.3 275.6 293.6 305.5 315.6 325.1 331.2 341.9 Terminal Sacrifice
49 10 25000PPM 93 93.8 126.5 154 173 205.3 223.2 236.5 250.3 262.2 273.2 281.4 291.5 293.7 303.5 Terminal Sacrifice
50 10 25000PPM 93 99.3 138.6 173.4 194 230.8 252.9 268.7 285.8 300.4 312 318.8 324 325.6 334.4 Terminal Sacrifice
51 11 50000PPM 93 98.7 126.8 160.7 184.4 218.6 238.7 253.7 270.7 284.6 295.6 307.6 322.6 324.6 336.2 Terminal Sacrifice
52 11 50000PPM 93 96.3 123.3 154.7 177.5 206.7 227.4 237.7 257 270.1 279.3 290.2 301.7 303.9 319.5 Terminal Sacrifice
53 11 50000PPM 93 88.9 116.9 150.6 173.4 189.8 221.4 239.4 253.7 271.7 280.9 291.4 302.7 302.9 308.4 Terminal Sacrifice
54 11 50000PPM 93 92.2 119.9 157.1 182.8 217.9 242.7 257.6 278.6 293.7 304 316.6 327.2 329.3 336.7 Terminal Sacrifice
55 11 50000PPM 93 89.5 113.7 149.3 174.1 212.1 235 254.3 276.6 289.5 302.4 315.6 330.9 332.3 339.5 Terminal Sacrifice
56 12 50000PPM 93 103 129.5 166.8 190.5 173.8 230.4 249.8 266.5 275.5 289 296.4 306.7 310.3 311.9 Terminal Sacrifice
57 12 50000PPM 93 86.4 115 146 176.6 161.6 217.8 241.8 258.5 271.4 280 290.5 300.5 303.2 311.9 Terminal Sacrifice
58 12 50000PPM 93 89.1 113.1 141.8 167 154.8 205.6 224.1 241.7 245.9 256.7 265.2 277.1 282.9 296 Terminal Sacrifice
59 12 50000PPM 93 90.8 117.7 147.4 173.1 175.7 217 236.3 257.1 271.1 287.2 301.2 313.8 319.1 334.8 Terminal Sacrifice
60 12 50000PPM 93 90.3 121.5 156.8 184.6 170.2 227.6 253.3 272.7 280.4 292 301.7 315.7 318.6 331.1 Terminal Sacrifice
* All body weights in grams