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Clinical Chemistry Individual Animal

Study Information:

Chemical Name: Sodium Nitrite
CASRN: ="7632-00-0"
Study Number: C88007
Study Length (Year Completed): 13 Weeks (N/A)
Exposure Route: WATER
TDMS Number: 8800701.ss
Sex: Female
Strain and Species: Fischer 344 Rats

Clinical Chemistry Individual Animal Data
Measurement Time Animal Number Dose Group (%) Control Code BUN (mg_dL) Creat (U per L) TP (g_dL) ALB (g_dL) Serum Glucose (mg per dL) Creat Kinase (IU_L) ALT (IU_L) SDH (IU_L) ALP (IU_L) TBA (umol per g)
Day 5 0222 0 V 19 0.7 6.4 4.4 67 203 32 7 361 6
Day 5 0223 0 V 21 0.7 6.2 4.3 83 272 44 11 358 10
Day 5 0224 0 V 20 0.8 6.7 4.6 306 45 9 485 16
Day 5 0225 0 V 18 0.6 6.2 4.3 77 540 30 10 318 3
Day 5 0228 0 V 23 0.6 6 4.1 92 206 39 7 438 19
Day 5 0229 0 V 30 5.4 4.1 114 1223 67 22 385
Day 5 0230 0 V 20 0.7 5.9 4 192 38 8 467 19
Day 5 0231 0 V 25 0.6 5.9 4 53 717 34 11 478 25
Day 5 0233 0 V 21 0.5 6.1 4 96 242 32 10 424 5
Day 5 0235 0 V 24 0.5 6 4.1 85 415 49 12 528 11
Day 5 0252 0.075 83 2224 36 13 469
Day 5 0253 0.075 22 0.6 6.2 4.6 90 182 41 11 433 10
Day 5 0257 0.075 22 0.7 6.1 4.3 88 289 37 9 407 60
Day 5 0258 0.075 20 0.8 6.5 4.5 50 404 42 10 363 19
Day 5 0259 0.075 23 0.9 6.3 4.5 107 205 45 9 469
Day 5 0260 0.075 19 0.6 5.9 4.1 93 258 29 10 348 14
Day 5 0262 0.075 22 0.6 5.8 4.1 71 740 49 13 394 8
Day 5 0263 0.075 19 0.8 6.4 4.6 70 574 41 10 369 18
Day 5 0264 0.075 21 0.7 6.1 4.6 1337 48 10 442 25
Day 5 0265 0.075 24 0.6 6.2 4.1 534 36 10 453 14
Day 5 0266 0.15 23 0.7 6.3 4.1 501 39 12 386 11
Day 5 0267 0.15 20 0.7 6.5 4.7 92 229 36 6 331 47
Day 5 0270 0.15 18 0.7 6.6 4.7 100 304 37 9 393 8
Day 5 0272 0.15 20 0.7 6.5 4.5 72 227 42 8 360 28
Day 5 0273 0.15 19 0.6 6.4 4.4 89 486 33 9 360 9
Day 5 0275 0.15 21 0.6 6.6 4.8 94 237 41 11 440 6
Day 5 0276 0.15 23 0.6 5.8 4.4 100 540 45 16 365 12
Day 5 0278 0.15 18 0.6 6.3 4.5 67 282 29 9 328 9
Day 5 0279 0.15 5.9 87 765 41 13 431
Day 5 0283 0.3 19 6.2 4.3 71 370 34 7 412
Day 5 0285 0.3 21 0.7 6.1 4.3 85 233 37 6 323 18
Day 5 0286 0.3 21 0.7 6.6 4.9 113 202 34 11 360 13
Day 5 0288 0.3 21 0.7 6.4 4.5 78 318 35 9 307 24
Day 5 0289 0.3 22 0.7 6.1 4.3 83 376 34 17 331 6
Day 5 0290 0.3 19 0.7 6 4.4 85 242 38 9 315 18
Day 5 0292 0.3 24 0.8 6.6 4.9 102 140 43 8 404 7
Day 5 0293 0.3 23 0.7 5.9 4.1 696 40 8 340 19
Day 5 0294 0.3 20 0.7 6.1 4.7 111 314 34 12 330 5
Day 5 0295 0.3 20 0.7 6.1 4.1 92 1087 43 9 331 12
Day 5 0238 0.375 19 0.7 6.2 4.3 73 278 41 11 389 17
Day 5 0239 0.375 20 0.5 6.2 4.5 94 246 36 9 403 24
Day 5 0241 0.375 20 0.6 6.1 4.6 78 429 38 9 393 9
Day 5 0242 0.375 20 0.6 5.9 4.1 89 381 38 7 404 6
Day 5 0243 0.375 22 0.6 6.1 4 115 188 30 10 488 14
Day 5 0244 0.375 23 0.6 5.9 4 809 36 11 435 17
Day 5 0245 0.375 21 0.6 6.5 4.5 72 200 32 12 373 4
Day 5 0247 0.375 21 0.8 6.3 4.5 117 43 4 422 13
Day 5 0248 0.375 25 0.6 6.4 4.9 916 37 9 500 8
Day 5 0296 0.5 25 0.6 5.9 4.2 118 227 36 10 365 12
Day 5 0297 0.5 23 6.1 4.3 115 3768 65 16 239
Day 5 0298 0.5 21 0.8 6.3 4.8 119 501 41 11 325 26
Day 5 0299 0.5 21 0.8 6.2 4.5 80 405 61 28 325 34
Day 5 0300 0.5 20 0.7 5.7 4.1 388 36 7 328 13
Day 5 0302 0.5 23 0.6 5.9 4.6 94 1708 46 11 338
Day 5 0303 0.5 22 0.8 6.2 4.3 116 513 37 11 274 8
Day 5 0307 0.5 21 0.9 5.7 4.1 111 308 43 9 296 26
Day 5 0308 0.5 23 0.7 6.6 4.7 87 463 38 9 305 6
Day 5 0310 0.5 26 0.7 6.1 4.2 937 41 14 354 14
Day 19 0221 0 V 21 0.6 5.9 4.3 66 228 33 11 370 11
Day 19 0224 0 V 6.1 4.3 79 3260 42 15 315
Day 19 0225 0 V 22 0.5 5.6 4 92 1988 40 14 288 57
Day 19 0227 0 V 24 0.6 6.6 4.6 102 203 31 12 338 8
Day 19 0228 0 V 26 0.5 5.5 4.2 93 276 33 11 367 10
Day 19 0229 0 V 26 0.8 6.1 4.2 110 684 40 12 347 36
Day 19 0230 0 V 27 6 4.1 55 52 13 380 35
Day 19 0232 0 V 30 0.6 6.2 4.4 102 229 32 13 335 10
Day 19 0234 0 V 22 0.5 6.4 4.4 91 167 41 13 367 11
Day 19 0235 0 V 22 0.5 6.2 4.3 93 226 33 12 391 12
Day 19 0251 0.075 20 0.6 6.4 4.5 86 331 23 10 321 8
Day 19 0252 0.075 22 0.5 6.5 4.5 59 344 32 14 351 19
Day 19 0253 0.075 23 0.6 6.2 4.3 62 547 37 14 321 9
Day 19 0255 0.075 23 0.6 6.7 4.5 84 268 31 10 349 8
Day 19 0256 0.075 26 0.7 5.8 4.4 60 436 29 12 348 22
Day 19 0257 0.075 22 0.6 6.4 4.5 84 223 29 11 324 15
Day 19 0259 0.075 24 0.6 5.8 4.4 86 129 35 8 343 21
Day 19 0260 0.075 25 0.6 6.2 4.7 85 242 37 11 369 9
Day 19 0262 0.075 24 0.6 6.3 4.5 256 40 14 342 39
Day 19 0264 0.075 23 0.6 6.1 4.4 110 147 35 12 330 18
Day 19 0266 0.15 25 0.6 5.9 4.4 98 255 31 12 313 12
Day 19 0267 0.15 23 0.6 6 4.2 329 31 14 247 12
Day 19 0269 0.15 26 0.6 6.8 4.8 154 38 11 368 11
Day 19 0272 0.15 24 0.7 6 4.7 108 254 32 11 261 10
Day 19 0274 0.15 23 0.6 6.9 4.8 74 148 34 15 314 11
Day 19 0275 0.15 21 0.8 5.4 4 79 226 35 12 342 23
Day 19 0276 0.15 25 0.7 6.7 4.5 94 176 42 13 339 7
Day 19 0278 0.15 24 0.7 6.1 4.5 100 194 38 10 259 18
Day 19 0279 0.15 25 0.8 6.6 4.4 81 218 49 14 410 14
Day 19 0280 0.15 23 0.8 6.5 4.5 84 338 44 14 292 11
Day 19 0281 0.3 23 0.8 6.8 4.6 84 350 36 14 306 7
Day 19 0283 0.3 25 0.8 6.6 4.4 77 664 45 15 400 15
Day 19 0284 0.3 24 0.6 6.5 4.8 87 243 36 12 315 20
Day 19 0285 0.3 20 0.7 5.6 4.4 85 258 30 15 260 7
Day 19 0287 0.3 25 0.9 6.2 4.1 83 358 46 15 275 12
Day 19 0289 0.3 25 0.9 5.9 4.1 325 41 17 236 17
Day 19 0291 0.3 23 0.7 5.7 4.1 81 498 46 14 277 8
Day 19 0292 0.3 23 0.7 5.8 4.3 91 595 35 10 304 15
Day 19 0293 0.3 27 0.6 5.7 4.1 408 31 15 223 34
Day 19 0294 0.3 26 0.6 6.3 4.7 134 32 13 286 13
Day 19 0237 0.375 24 0.7 6.5 4.4 59 190 37 14 272 9
Day 19 0239 0.375 23 0.8 6.3 4.3 265 42 13 345 23
Day 19 0240 0.375 24 0.8 6.4 4.3 68 382 33 15 286 11
Day 19 0241 0.375 25 0.6 6.4 4.5 101 196 33 14 324 30
Day 19 0242 0.375 26 0.6 6.5 4.6 328 35 12 318 12
Day 19 0243 0.375 23 0.6 6.2 4.5 91 186 33 10 131 20
Day 19 0245 0.375 26 0.6 5.9 4.7 88 274 30 11 322 7
Day 19 0246 0.375 21 0.6 5.7 4.3 86 431 33 12 280 19
Day 19 0248 0.375 28 0.6 6.4 4.5 91 261 35 14 393 13
Day 19 0250 0.375 22 0.6 5.9 4.5 80 161 34 12 315 10
Day 19 0297 0.5 35 0.8 5.9 4.6 96 406 37 14 246 7
Day 19 0298 0.5 29 0.7 6.4 4.6 127 366 35 14 280 14
Day 19 0299 0.5 31 0.7 6.5 4.7 108 226 34 11 255 14
Day 19 0300 0.5 32 0.8 6.3 4.4 92 354 40 16 254 8
Day 19 0304 0.5 28 0.9 5.8 4.4 84 580 44 12 258 15
Day 19 0305 0.5 27 0.8 5.6 4.3 90 260 43 15 252 15
Day 19 0306 0.5 30 1 6.7 4.5 103 414 42 12 279 40
Day 19 0307 0.5 32 0.8 5.7 4.4 94 588 38 14 248 16
Day 19 0308 0.5 33 0.8 6.1 4.2 91 1002 45 13 245 20
Day 19 0309 0.5 29 0.8 6.5 4.7 98 322 43 16 254 9
Week 13 0061 0 V 21 0.6 7.1 4.8 71 79 41 7 180 17
Week 13 0062 0 V 19 0.7 6.5 4.5 81 66 33 6 181 19
Week 13 0063 0 V 16 0.7 6.6 4.6 73 44 46 6 179 34
Week 13 0064 0 V 17 0.7 6.8 4.6 57 25 51 6 154 15
Week 13 0065 0 V 19 0.6 6.8 4.4 115 42 8 186 13
Week 13 0066 0 V 19 0.6 6.6 4.4 94 95 39 7 189 15
Week 13 0067 0 V 17 0.7 6.9 4.6 80 62 47 7 152 24
Week 13 0068 0 V 14 0.7 6.8 4.5 96 51 53 173 11
Week 13 0069 0 V 19 0.7 6.6 4.4 92 140 42 5 173 15
Week 13 0070 0 V 17 0.6 7 4.6 75 268 59 14 210 13
Week 13 0081 0.075 22 0.7 7 4.7 83 111 40 9 207 40
Week 13 0082 0.075 18 0.7 7.4 5.1 96 64 39 8 172 12
Week 13 0083 0.075 21 0.6 6.5 4.3 77 54 43 3 196 31
Week 13 0084 0.075 20 0.7 7.1 4.8 84 54 53 6 193 26
Week 13 0085 0.075 18 0.6 7.1 4.8 89 34 39 5 174 11
Week 13 0086 0.075 19 0.7 6.9 4.8 81 34 60 7 170 27
Week 13 0087 0.075 18 0.7 7.2 4.8 80 36 41 4 183 42
Week 13 0088 0.075 18 0.7 6.5 4.5 93 97 36 7 183 11
Week 13 0089 0.075 21 0.6 7.3 5.1 80 39 6 158 41
Week 13 0090 0.075 15 0.7 6.8 4.8 110 40 6 168 10
Week 13 0091 0.15 23 0.8 7 4.9 90 24 66 16 165 102
Week 13 0092 0.15 20 0.6 6.8 4.6 84 80 41 7 165 30
Week 13 0093 0.15 24 0.7 7.1 4.8 82 96 48 8 182 16
Week 13 0094 0.15 22 0.6 6.8 4.5 100 99 47 5 180 38
Week 13 0095 0.15 21 0.7 7.5 4.8 88 42 45 5 151 27
Week 13 0096 0.15 21 0.8 7.6 5.2 93 39 50 7 161 10
Week 13 0097 0.15 23 0.6 7.1 5 89 34 46 6 165 35
Week 13 0098 0.15 20 0.6 6.7 4.6 86 76 50 8 171 9
Week 13 0099 0.15 22 0.7 7.2 5 86 40 60 6 154 17
Week 13 0100 0.15 21 0.7 7.1 4.9 85 164 74 11 175 16
Week 13 0101 0.3 21 0.8 7.3 4.9 82 98 48 7 158 41
Week 13 0102 0.3 21 0.6 7.1 4.7 105 35 48 7 174 18
Week 13 0103 0.3 24 0.6 6.5 4.4 86 74 59 9 159 16
Week 13 0104 0.3 26 0.7 6.9 4.7 70 31 49 4 160 11
Week 13 0105 0.3 22 0.6 6.9 4.6 86 87 49 7 174 30
Week 13 0106 0.3 22 0.7 6.9 4.7 89 29 61 5 160 29
Week 13 0107 0.3 19 0.7 7.3 4.8 87 54 52 8 178 28
Week 13 0109 0.3 24 0.8 6.9 4.6 81 55 64 9 152 36
Week 13 0110 0.3 22 0.6 7.5 5.1 72 79 50 4 161 16
Week 13 0071 0.375 19 0.6 7 4.6 74 42 41 5 176 28
Week 13 0072 0.375 18 0.8 7.2 4.7 79 27 45 14 139 24
Week 13 0073 0.375 18 0.7 7.7 5.1 88 48 40 6 190 10
Week 13 0074 0.375 17 0.7 6.9 4.6 77 87 42 8 212 10
Week 13 0075 0.375 19 0.6 6.4 4.5 75 27 47 5 197 21
Week 13 0076 0.375 20 0.8 7.2 4.8 75 34 43 4 196 27
Week 13 0077 0.375 21 0.6 7.6 5 88 127 34 6 140 7
Week 13 0078 0.375 21 0.7 7.7 5.2 72 87 46 8 172 27
Week 13 0079 0.375 18 0.7 7.2 5 71 48 5 173 41
Week 13 0080 0.375 19 0.6 6.7 4.5 85 155 34 9 167 7
Week 13 0111 0.5 21 0.6 6.9 4.9 73 149 53 9 171 92
Week 13 0112 0.5 22 0.7 6.9 4.8 72 121 34 7 133 22
Week 13 0113 0.5 19 0.7 6.6 4.7 82 131 37 10 139 43
Week 13 0114 0.5 24 0.8 6.3 4.5 69 145 56 14 140 24
Week 13 0115 0.5 22 0.7 6.4 4.6 85 49 55 9 166 45
Week 13 0116 0.5 21 0.6 6.9 5 130 45 11 126 25
Week 13 0117 0.5 24 0.7 6.2 4.5 89 82 62 11 140 16
Week 13 0118 0.5 21 0.7 6.8 4.9 70 133 46 8 136 24
Week 13 0119 0.5 19 0.7 6.8 4.9 96 44 10 126 26
Week 13 0120 0.5 22 0.7 6.8 4.9 78 58 52 9 143 3
Abbreviations:
NA: Not Available, V: Vehicle Control, BUN: Urea Nitrogen, Creat: Creatinine, TP: Protein Total, ALB: Albumin, Serum Glucose: Glucose, Creat Kinase: Creatine Kinase, ALT: Alanine Aminotransferase, SDH: Sorbitol Dehydrogenase, ALP: Alkaline Phosphatase, TBA: Bile Acids Per G Tissue