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Clinical Chemistry Individual Animal

Study Information:

Chemical Name: Sodium Nitrite
CASRN: ="7632-00-0"
Study Number: C88007
Study Length (Year Completed): 13 Weeks (N/A)
Exposure Route: WATER
TDMS Number: 8800701.ss
Sex: Male
Strain and Species: Fischer 344 Rats

Clinical Chemistry Individual Animal Data
Measurement Time Animal Number Dose Group (%) Control Code BUN (mg_dL) Creat (U per L) TP (g_dL) ALB (g_dL) Serum Glucose (mg per dL) Creat Kinase (IU_L) ALT (IU_L) SDH (IU_L) ALP (IU_L) TBA (umol per g)
Day 5 0132 0 V 22 0.6 6 4 111 462 45 15 495 8
Day 5 0134 0 V 20 0.7 6.5 4.3 94 528 47 7 598 32
Day 5 0135 0 V 18 0.6 6.6 4.3 67 141 46 9 542 11
Day 5 0136 0 V 23 0.6 6.8 4.3 91 264 51 8 625 8
Day 5 0137 0 V 20 0.6 6.8 4.4 82 376 39 9 600 7
Day 5 0138 0 V 22 0.6 6.6 4.3 85 276 41 8 568 10
Day 5 0139 0 V 19 0.7 6.7 4.5 67 1131 58 17 584 29
Day 5 0140 0 V 20 0.6 6.8 4.4 277 43 7 579 17
Day 5 0141 0 V 19 0.6 6.4 4.3 96 282 41 6 563 9
Day 5 0142 0 V 21 0.6 5.8 4 113 108 41 7 544 7
Day 5 0163 0.075 21 0.7 6.2 4.3 104 192 41 10 455 26
Day 5 0164 0.075 22 0.8 5.8 4.1 105 106 38 8 428 13
Day 5 0165 0.075 23 0.7 5.9 4 84 194 39 16 437 8
Day 5 0166 0.075 19 0.7 5.6 4.1 112 73 34 6 397 6
Day 5 0167 0.075 24 0.6 6.3 4.3 104 113 36 13 443 16
Day 5 0169 0.075 21 0.7 5.7 3.9 108 281 43 23 432 13
Day 5 0170 0.075 20 0.7 6.3 4.3 71 369 39 13 465 11
Day 5 0171 0.075 23 0.9 6 4 83 163 49 5 444 14
Day 5 0172 0.075 21 0.7 6.3 4.2 112 46 9 479 10
Day 5 0175 0.075 23 0.7 5.9 4.2 114 315 34 14 474 12
Day 5 0177 0.15 19 0.6 6.3 4 103 176 38 7 519 24
Day 5 0178 0.15 23 0.6 6.2 4.2 92 243 44 17 495 11
Day 5 0180 0.15 18 0.7 6.5 4.3 366 42 10 554 19
Day 5 0182 0.15 17 0.6 6.2 4.4 95 131 35 8 514 10
Day 5 0185 0.15 25 0.6 6.7 4.3 223 43 9 606 9
Day 5 0186 0.15 19 0.6 6.4 4.3 93 281 44 11 543 7
Day 5 0187 0.15 22 0.8 6.2 4.1 88 139 44 8 567 11
Day 5 0189 0.15 19 0.6 5.9 4.1 49 214 38 10 557 12
Day 5 0190 0.15 15 0.5 6.1 4.3 88 429 52 21 540 44
Day 5 0191 0.3 20 0.7 5.9 4.1 105 144 37 9 493 9
Day 5 0192 0.3 17 0.5 6.3 4.3 122 356 38 10 546 13
Day 5 0194 0.3 18 0.6 6.6 4.3 85 304 37 10 522 24
Day 5 0195 0.3 21 0.8 6.1 4.1 318 48 32 508 10
Day 5 0196 0.3 18 0.8 6.2 4.2 118 221 50 6 503 33
Day 5 0197 0.3 22 1 6.3 4 92 446 70 9 528 16
Day 5 0198 0.3 21 0.7 6.5 4.2 93 441 44 8 458 10
Day 5 0199 0.3 19 0.7 5.7 4 91 354 39 21 486 6
Day 5 0201 0.3 22 0.7 6.4 4.2 80 184 48 9 518 6
Day 5 0203 0.3 21 0.6 6.1 4.1 180 36 10 474 13
Day 5 0146 0.375 15 0.7 6.7 4.3 95 593 59 12 512 68
Day 5 0149 0.375 17 0.7 6.2 4.4 667 44 14 594 28
Day 5 0150 0.375 20 0.6 6.5 4.3 82 259 41 12 606 13
Day 5 0151 0.375 15 0.6 6.4 4 107 248 40 12 554 20
Day 5 0153 0.375 21 0.7 6 4.3 365 45 15 569 17
Day 5 0154 0.375 20 0.6 6.4 4.2 88 152 44 7 595 24
Day 5 0155 0.375 18 0.7 6.4 4.5 92 421 43 9 556 24
Day 5 0156 0.375 18 0.7 6.6 4.3 76 449 41 17 604 20
Day 5 0157 0.375 18 0.7 6.3 4.5 361 45 11 682 15
Day 5 0158 0.375 21 0.6 6.6 4.2 88 452 37 17 588 17
Day 5 0208 0.5 21 0.7 5.7 4 111 222 43 17 447 6
Day 5 0209 0.5 22 0.6 5.9 4.1 164 111 41 9 440 8
Day 5 0210 0.5 20 0.7 6.2 4.2 116 247 35 11 407 6
Day 5 0212 0.5 24 0.6 6.1 4.3 77 184 37 11 434 7
Day 5 0214 0.5 21 0.7 5.9 4.1 67 194 38 12 459 14
Day 5 0215 0.5 20 0.7 6 4.2 72 172 36 14 423 7
Day 5 0217 0.5 24 0.8 6.1 4.1 116 307 48 11 449 18
Day 5 0218 0.5 23 0.8 6.7 4.4 89 154 45 10 444 10
Day 5 0219 0.5 18 0.7 6.2 4.3 80 245 35 14 461 7
Day 5 0220 0.5 20 0.6 5.9 4.2 125 150 25 7 441 5
Day 19 0131 0 V 19 0.7 6.9 4.5 65 37 7 439 11
Day 19 0132 0 V 19 0.5 6.9 4.4 80 791 38 12 411 10
Day 19 0134 0 V 20 0.7 6.7 4.6 92 183 44 12 481 25
Day 19 0135 0 V 21 0.8 6.3 4.4 91 120 57 14 439 15
Day 19 0136 0 V 18 0.6 6.4 4.3 99 131 42 8 467 6
Day 19 0138 0 V 21 0.6 6.3 4.2 114 484 39 11 425 9
Day 19 0142 0 V 23 0.7 6.3 4.1 92 189 58 10 482 13
Day 19 0143 0 V 20 0.6 6.3 4.2 92 485 45 13 412 7
Day 19 0144 0 V 24 0.7 7.5 4.8 84 207 53 12 470 4
Day 19 0145 0 V 25 0.7 7.6 4.8 69 1375 70 18 451 53
Day 19 0162 0.075 22 0.8 6.8 4.4 86 153 48 10 426 13
Day 19 0163 0.075 20 0.6 6.8 4.5 92 118 45 10 455 15
Day 19 0164 0.075 21 0.5 6.7 4.5 87 480 40 12 439
Day 19 0165 0.075 18 0.7 7.1 4.4 82 175 42 10 481 24
Day 19 0167 0.075 23 0.7 6.4 4.3 148 196 49 10 419 7
Day 19 0170 0.075 21 0.6 6.9 4.5 119 245 45 11 445 8
Day 19 0171 0.075 18 0.6 6.8 4.3 89 297 40 9 461 11
Day 19 0172 0.075 22 0.6 6.9 4.5 86 2402 68 14 497 24
Day 19 0173 0.075 22 0.6 7.1 4.7 93 123 47 10 454 10
Day 19 0174 0.075 21 0.7 7 4.5 99 199 37 10 421 10
Day 19 0177 0.15 20 0.7 6.4 4.4 85 257 39 10 446 14
Day 19 0178 0.15 22 0.9 6.5 4.2 77 172 54 12 372 16
Day 19 0179 0.15 25 0.7 6 4.1 120 449 92 30 334 18
Day 19 0180 0.15 22 0.6 6.6 4.3 96 381 43 11 410 26
Day 19 0182 0.15 23 0.7 6.7 4.5 90 94 50 9 431 8
Day 19 0186 0.15 23 0.6 7.4 4.7 82 124 65 14 451 3
Day 19 0187 0.15 24 0.6 7 4.1 100 54 35 4 440 9
Day 19 0188 0.15 21 0.7 6.8 4.6 94 171 49 12 485 10
Day 19 0189 0.15 103 2282 18 428
Day 19 0190 0.15 21 0.8 7 4.6 806 66 14 436 17
Day 19 0191 0.3 23 0.6 7.4 4.8 118 87 39 6 396 9
Day 19 0192 0.3 23 0.7 6.8 4.4 80 271 42 12 386 6
Day 19 0193 0.3 23 0.6 6.4 4.4 123 356 47 11 363 8
Day 19 0198 0.3 22 0.6 6.4 4.4 115 230 45 12 394 11
Day 19 0199 0.3 21 0.8 6.5 4.3 120 280 51 16 422 5
Day 19 0200 0.3 21 0.7 6.2 4.3 88 367 53 15 403 7
Day 19 0201 0.3 21 0.8 6.2 4.2 116 332 47 13 398 8
Day 19 0203 0.3 21 0.7 6.7 4.5 97 223 46 14 429 6
Day 19 0204 0.3 23 0.8 7 4.5 92 111 49 11 406 9
Day 19 0205 0.3 22 0.6 6.7 4.4 96 82 41 10 426 10
Day 19 0146 0.375 21 0.6 7.1 4.7 84 201 41 11 433 7
Day 19 0147 0.375 20 0.6 6.9 4.5 110 287 44 10 462 9
Day 19 0150 0.375 23 0.6 7.2 4.6 556 39 12 434 55
Day 19 0153 0.375 23 0.8 7.3 4.6 187 50 16 442 17
Day 19 0155 0.375 20 0.6 6.2 4.4 98 277 42 12 457 7
Day 19 0156 0.375 21 0.6 6.9 4.4 71 347 37 11 447 2
Day 19 0157 0.375 21 0.7 7 4.4 130 480 39 10 505 13
Day 19 0158 0.375 21 0.6 7 4.6 94 117 50 12 466 13
Day 19 0159 0.375 23 0.6 7.1 4.6 88 56 36 7 482 13
Day 19 0160 0.375 21 0.6 7.1 4.5 86 228 45 13 423 6
Day 19 0207 0.5 27 0.9 6 4.2 130 338 66 23 400 13
Day 19 0208 0.5 25 0.9 6.5 4.4 88 366 47 15 350 27
Day 19 0210 0.5 24 0.9 6.8 4.5 78 454 46 12 290 14
Day 19 0212 0.5 23 0.7 6.7 4.4 92 237 41 13 315 6
Day 19 0213 0.5 21 0.7 6.2 4.3 116 314 42 13 329 9
Day 19 0214 0.5 25 0.8 6.7 4.3 130 295 41 16 304 18
Day 19 0215 0.5 28 0.6 6.5 4.4 122 105 34 9 299 8
Day 19 0217 0.5 27 0.7 6.1 4.3 128 296 42 16 369 11
Day 19 0218 0.5 26 0.7 6.3 4.3 160 166 47 12 343 10
Day 19 0219 0.5 23 0.7 6.2 4.3 803 39 10 327 9
Week 13 0001 0 V 19 0.7 6.7 4.6 58 80 64 8 216 4
Week 13 0002 0 V 17 0.7 6.2 4.2 107 56 18 203 5
Week 13 0003 0 V 18 0.6 6.8 4.3 64 76 38 16 218 6
Week 13 0004 0 V 18 0.6 6.9 4.3 67 51 42 6 199
Week 13 0005 0 V 16 0.7 7.1 4.5 61 76 53 6 211 5
Week 13 0006 0 V 15 0.6 6.7 4.4 61 55 5 196 6
Week 13 0007 0 V 19 0.7 6.5 4.2 328 53 33 214 4
Week 13 0008 0 V 17 0.8 6.7 4.3 73 288 57 33 206 11
Week 13 0009 0 V 20 0.7 7 4.5 59 43 41 8 247 4
Week 13 0010 0 V 19 0.7 6.8 4.6 64 94 56 7 245 6
Week 13 0021 0.075 22 0.7 7.2 4.7 69 64 44 7 222
Week 13 0022 0.075 20 0.7 7 4.6 61 82 32 19 218 5
Week 13 0023 0.075 22 0.6 6.8 4.6 77 137 49 10 237 44
Week 13 0024 0.075 21 0.8 7 4.4 73 119 60 32 206 21
Week 13 0025 0.075 24 0.7 7 4.7 96 60 16 230 6
Week 13 0026 0.075 23 0.7 7.3 4.9 84 200 61 10 267
Week 13 0027 0.075 19 0.7 7.1 4.5 65 172 50 24 212 12
Week 13 0028 0.075 19 0.6 6.7 4.3 64 347 58 23 212 8
Week 13 0029 0.075 24 0.7 7 4.7 87 46 111 16 292 8
Week 13 0030 0.075 18 0.7 6.8 4.3 86 48 10 215 5
Week 13 0031 0.15 23 0.7 7 4.5 72 118 75 22 216 8
Week 13 0032 0.15 22 0.8 6.9 4.3 85 49 50 13 186 14
Week 13 0033 0.15 24 0.7 7.1 4.6 76 128 45 8 218 26
Week 13 0034 0.15 17 0.7 7.2 4.8 62 74 44 12 217 12
Week 13 0035 0.15 19 0.7 7.1 4.4 62 73 48 12 216 8
Week 13 0036 0.15 22 0.7 7.2 4.5 69 97 52 14 230 8
Week 13 0037 0.15 17 0.7 7.2 4.6 70 47 51 7 194 15
Week 13 0038 0.15 21 0.7 6 4.8 71 91 38 7 194 18
Week 13 0039 0.15 21 0.7 6.8 4.3 69 220 47 31 177 19
Week 13 0040 0.15 18 0.7 7 4.3 940 55 45 238 11
Week 13 0041 0.3 18 0.7 6.9 4.7 71 294 43 29 206 17
Week 13 0042 0.3 22 0.7 6.9 4.5 80 79 41 8 217
Week 13 0043 0.3 20 0.7 7 4.5 63 158 54 42 205 7
Week 13 0044 0.3 25 0.7 7.2 4.9 77 304 67 9 234
Week 13 0045 0.3 17 0.7 7 4.7 72 89 57 16 186 21
Week 13 0046 0.3 19 0.7 6.7 4.4 126 47 17 192 9
Week 13 0047 0.3 22 0.6 7 4.5 72 99 104 33 218 6
Week 13 0048 0.3 23 0.7 6.9 4.4 59 115 43 23 226 7
Week 13 0049 0.3 32 0.7 7 4.7 82 91 51 5 244 1
Week 13 0050 0.3 25 0.7 7.3 4.8 73 71 50 7 205
Week 13 0011 0.375 23 0.7 7.1 4.5 66 61 19 246 5
Week 13 0012 0.375 23 0.7 7 4.7 87 62 53 7 219
Week 13 0013 0.375 22 7 4.3 428 41 42 204
Week 13 0014 0.375 21 0.7 7.1 4.4 59 256 39 9 217 5
Week 13 0015 0.375 16 0.7 6.6 4.2 67 49 41 6 206 7
Week 13 0016 0.375 21 0.7 7.3 4.9 68 184 59 7 281
Week 13 0017 0.375 18 0.8 6.5 4.3 63 34 43 1 204 7
Week 13 0018 0.375 20 0.6 6.8 4.8 54 59 43 7 242
Week 13 0019 0.375 17 0.7 7.2 4.6 76 56 66 9 235 8
Week 13 0020 0.375 24 0.7 6.9 4.7 66 127 49 6 272 6
Week 13 0051 0.5 22 0.6 6.7 4.4 68 266 35 28 213 4
Week 13 0052 0.5 19 0.7 6.3 4.3 69 143 48 27 190 7
Week 13 0053 0.5 25 0.7 6.5 4.6 86 74 50 7 261
Week 13 0054 0.5 20 0.7 6.1 4.3 75 102 36 17 182 5
Week 13 0055 0.5 21 0.8 6.9 4.5 71 111 41 33 211
Week 13 0056 0.5 25 0.7 6.2 4.2 72 137 51 41 205 6
Week 13 0057 0.5 21 0.7 6.4 4.3 73 71 46 9 219 7
Week 13 0058 0.5 23 0.7 6.5 4.5 76 202 52 10 202
Week 13 0059 0.5 19 0.6 7 4.6 67 91 47 16 206 6
Week 13 0060 0.5 25 0.7 6.7 4.7 81 114 53 6 212
Abbreviations:
NA: Not Available, V: Vehicle Control, BUN: Urea Nitrogen, Creat: Creatinine, TP: Protein Total, ALB: Albumin, Serum Glucose: Glucose, Creat Kinase: Creatine Kinase, ALT: Alanine Aminotransferase, SDH: Sorbitol Dehydrogenase, ALP: Alkaline Phosphatase, TBA: Bile Acids Per G Tissue