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Clinical Chemistry Individual Animal

Study Information:

Chemical Name: alpha/beta Thujone Mixture
CASRN: ="76231-76-0"
Study Number: C99037B
Study Length (Year Completed): 13 Weeks (N/A)
Exposure Route: GAV
TDMS Number: 9903703.fixtime
Sex: Female
Strain and Species: Fischer 344 Rats

Clinical Chemistry Individual Animal Data
Measurement Time Animal Number Dose Group (mg/kg) Control Code BUN (mg_dL) Creat (U per L) TP (g_dL) ALB (g_dL) Creat Kinase (IU_L) ALT (IU_L) SDH (IU_L) ALP (IU_L) TBA (umol per g)
Day 93 0061 0 V 16.5 0.6 6.2 4.5 157 57 22.3 218 25.5
Day 93 0062 0 V 16.6 0.6 6.3 4.6 244 58 18.1 162 30.2
Day 93 0063 0 V 17.5 0.7 5.9 4.4 221 66 26.4 181 41.4
Day 93 0064 0 V 16.5 0.6 6.4 4.6 289 70 16.0 174 30.7
Day 93 0065 0 V 17.2 0.7 6.0 4.5 265 68 16.3 189 14.3
Day 93 0066 0 V 16.5 0.6 6.1 4.6 136 85 19.9 227 25.0
Day 93 0067 0 V 18.8 0.6 5.8 4.4 267 88 20.2 201 16.8
Day 93 0068 0 V 17.5 0.6 6.0 4.4 132 131 32.3 209 30.0
Day 93 0069 0 V 13.6 0.6 6.3 4.9 302 47 12.2 177 16.8
Day 93 0070 0 V 16.0 0.6 6.5 4.7 193 68 19.1 179 35.1
Day 93 0071 12.5 15.4 0.6 6.3 4.6 165 47 17.5 206 15.7
Day 93 0072 12.5 16.8 0.6 6.1 4.6 318 57 19.0 212 24.2
Day 93 0073 12.5 17.0 0.6 6.4 4.8 291 72 17.7 208 36.9
Day 93 0074 12.5 15.9 0.5 6.7 4.7 169 46 14.4 139 29.5
Day 93 0075 12.5 16.9 0.6 6.1 4.4 360 117 19.9 178 24.8
Day 93 0076 12.5 16.0 0.6 5.6 4.2 154 65 22.2 187 28.3
Day 93 0077 12.5 16.6 0.6 6.2 4.5 212 68 17.3 189 38.9
Day 93 0078 12.5 15.4 0.6 6.8 5.0 245 73 22.5 208 33.9
Day 93 0079 12.5 15.9 0.6 6.4 4.8 208 71 13.4 146 37.1
Day 93 0080 12.5 16.7 0.6 6.6 4.8 277 50 11.7 174 26.9
Day 93 0081 25 16.4 0.6 6.4 4.6 168 73 22.9 195 48.3
Day 93 0082 25 16.4 0.6 6.8 5.0 163 71 21.3 184 30.0
Day 93 0083 25 12.5 0.6 5.6 4.2 412 46 2.7 172 34.2
Day 93 0084 25 18.0 0.7 6.6 4.8 282 64 21.0 146 32.3
Day 93 0085 25 17.8 0.6 7.1 5.0 221 127 30.4 170 39.9
Day 93 0086 25 17.3 0.6 6.2 4.6 204 50 20.2 161 36.8
Day 93 0087 25 13.3 0.5 6.3 4.7 314 45 9.3 163 41.2
Day 93 0088 25 15.3 0.6 6.2 4.6 166 92 27.2 199 19.8
Day 93 0089 25 14.0 0.6 6.3 4.8 173 84 23.5 187 53.5
Day 93 0090 25 17.9 0.6 5.9 4.5 249 136 30.0 193 45.4
Day 93 0091 50 17.3 0.5 5.9 4.3 148 53 16.6 221 31.2
Day 93 0092 50 19.0 0.7 6.1 4.3 172 52 14.1 231 16.6
Day 93 0093 50 18.4 0.6 6.3 4.5 289 73 20.2 164 45.0
Day 93 0094 50 15.3 0.6 6.6 4.7 262 52 9.2 172 29.3
Day 93 0095 50 19.3 0.6 6.2 4.5 237 68 20.0 215 64.4
Day 93 0096 50 21.0 0.7 6.0 4.4 168 41 15.3 183 22.6
Day 93 0097 50 14.0 0.6 6.7 4.6 233 67 16.8 220 51.8
Day 93 0098 50 16.2 0.6 6.2 4.5 211 53 19.9 182 28.7
Day 93 0099 50 18.2 0.7 5.9 4.4 173 63 17.6 183 35.4
Day 93 0100 50 20.3 0.6 5.7 4.3 398 62 10.9 189 27.6
Day 93 0101 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0102 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0103 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0104 75 15.5 0.6 5.9 4.3 232 45 11.0 199 35.7
Day 93 0105 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0106 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0107 75 16.9 0.7 6.1 4.5 221 51 20.1 203 71.5
Day 93 0108 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0109 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0110 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0111 100 16.4 0.6 6.2 4.4 242 37 14.4 209 15.8
Day 93 0112 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0113 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0114 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0115 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0116 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0117 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0118 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0119 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0120 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Abbreviations:
NA: Not Available, V: Vehicle Control, BUN: Urea Nitrogen, Creat: Creatinine, TP: Protein Total, ALB: Albumin, Creat Kinase: Creatine Kinase, ALT: Alanine Aminotransferase, SDH: Sorbitol Dehydrogenase, ALP: Alkaline Phosphatase, TBA: Bile Acids Per G Tissue