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Clinical Chemistry Individual Animal

Study Information:

Chemical Name: alpha/beta Thujone Mixture
CASRN: ="76231-76-0"
Study Number: C99037B
Study Length (Year Completed): 13 Weeks (N/A)
Exposure Route: GAV
TDMS Number: 9903703.fixtime
Sex: Male
Strain and Species: Fischer 344 Rats

Clinical Chemistry Individual Animal Data
Measurement Time Animal Number Dose Group (mg/kg) Control Code BUN (mg_dL) Creat (U per L) TP (g_dL) ALB (g_dL) Creat Kinase (IU_L) ALT (IU_L) SDH (IU_L) ALP (IU_L) TBA (umol per g)
Day 93 0001 0 V 17.0 0.6 6.4 4.4 152 120 26 211 38.2
Day 93 0002 0 V 14.5 0.6 6.7 4.4 252 108 22 204 15.4
Day 93 0003 0 V 15.3 0.6 6.6 4.6 113 95 21.8 249 18.5
Day 93 0004 0 V 14.9 0.7 6.9 4.6 236 140 42.3 219 49.6
Day 93 0005 0 V 15.1 0.6 6.5 4.5 178 86 23.6 204 14.7
Day 93 0006 0 V 14.0 0.6 6.2 4.3 171 113 32.6 222 15.4
Day 93 0007 0 V 15.1 0.6 6.4 4.4 149 81 31.5 247 16.3
Day 93 0008 0 V 14.9 0.6 6.4 4.3 188 121 41.9 205 30.8
Day 93 0009 0 V 14.0 0.6 6.0 4.3 323 77 25.9 220 27.1
Day 93 0010 0 V 11.2 0.6 6.8 4.5 280 149 28.9 221 17.9
Day 93 0011 12.5 20.8 0.7 6.6 4.4 112 69 19.7 237 40.3
Day 93 0012 12.5 10.5 0.7 6.5 4.4 184 80 19.8 268 16.5
Day 93 0013 12.5 18.0 0.5 6.8 4.7 120 79 21.9 229 14.2
Day 93 0014 12.5 13.8 0.7 6.3 4.4 224 64 17.9 244 10.8
Day 93 0015 12.5 15.4 0.7 6.4 4.4 150 61 20.7 225 17.6
Day 93 0016 12.5 16.0 0.6 6.0 4.1 233 54 18.1 211 19.1
Day 93 0017 12.5 15.8 0.7 6.6 4.3 168 66 18.5 222 23.6
Day 93 0018 12.5 17.7 0.7 6.3 4.2 211 79 26.0 227 16.2
Day 93 0019 12.5 16.7 0.6 6.6 4.4 260 96 26.6 226 17.1
Day 93 0020 12.5 18.6 0.7 6.7 4.4 257 63 22.6 229 22.5
Day 93 0021 25 16.4 0.7 6.6 4.4 127 50 12.5 237 19.3
Day 93 0022 25 15.9 0.7 6.8 4.5 139 53 13.3 223 16.2
Day 93 0023 25 16.4 0.7 6.6 4.4 144 62 16.9 233 16.7
Day 93 0024 25 16.2 0.8 6.8 4.6 232 62 18.8 254 28.3
Day 93 0025 25 17.3 0.7 6.6 4.7 305 78 28.0 224 19.0
Day 93 0026 25 11.7 0.9 6.1 4.2 169 57 18.8 208 38.5
Day 93 0027 25 16.0 0.7 6.5 4.4 283 65 23.4 219 18.1
Day 93 0028 25 14.6 0.6 6.7 4.5 129 51 17.2 206 16.4
Day 93 0029 25 16.0 0.6 6.7 4.5 142 71 22.5 232 17.6
Day 93 0030 25 15.2 0.7 6.6 4.3 146 57 18.8 240 16.8
Day 93 0031 50 15.7 0.7 6.2 4.2 136 42 11.0 224 41.6
Day 93 0032 50 16.0 0.7 6.7 4.5 117 47 10.7 245 14.9
Day 93 0033 50 17.5 0.7 6.3 4.3 201 54 5.0 222 39.3
Day 93 0034 50 18.3 0.8 6.9 4.7 190 107 31.0 244 31.0
Day 93 0035 50 18.8 0.8 6.8 4.4 178 61 18.6 261 35.1
Day 93 0036 50 16.9 0.7 5.8 4.0 162 66 20.1 207 17.1
Day 93 0037 50 16.5 0.7 6.5 4.4 130 50 19.3 213 25.1
Day 93 0038 50 14.9 0.7 6.5 4.1 247 44 12.6 211 28.3
Day 93 0039 50 14.5 0.5 6.7 4.5 121 47 15.1 219 18.6
Day 93 0040 50 11.6 1.0 6.2 4.3 120 41 9.8 160 22.0
Day 93 0041 75 12.7 0.7 6.2 4.3 134 51 10.8 256 14.3
Day 93 0042 75 12.2 0.7 6.4 4.5 114 51 12.5 237 20.2
Day 93 0043 75 11.6 0.7 6.5 4.6 125 55 10.7 250 14.0
Day 93 0044 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0045 75 12.9 0.7 6.4 4.4 168 56 15.0 232 15.1
Day 93 0046 75 10.7 0.7 5.2 3.5 227 24 10.9 107 13.6
Day 93 0047 75 15.6 0.7 6.2 4.2 141 54 21.4 188 30.2
Day 93 0048 75 16.2 0.8 6.6 4.5 164 65 22.8 229 16.6
Day 93 0049 75 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0050 75 14.5 0.7 6.6 4.4 186 45 14.8 214 24.6
Day 93 0051 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0052 100 16.9 0.7 6.3 4.4 113 45 14.3 253 20.0
Day 93 0053 100 14.8 0.7 6.6 4.6 208 20 10.0 227 17.1
Day 93 0054 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0055 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0056 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0057 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0058 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0059 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Day 93 0060 100 DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD DEAD
Abbreviations:
NA: Not Available, V: Vehicle Control, BUN: Urea Nitrogen, Creat: Creatinine, TP: Protein Total, ALB: Albumin, Creat Kinase: Creatine Kinase, ALT: Alanine Aminotransferase, SDH: Sorbitol Dehydrogenase, ALP: Alkaline Phosphatase, TBA: Bile Acids Per G Tissue