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Long-Term Study Organ Weights Individual Animal

Study Information:

Chemical Name: 3,3'-Dimethylbenzidine dihydrochloride
CASRN: ="612-82-8"
Study Number: C99990
Study Length (Year Completed): (N/A)
Exposure Route: DOSED WATER
TDMS Number: 0516601
Sex: Male
Strain and Species: F 344/N Rats

Organ Weights Individual Animal Data
Measurement Time Animal Number Dose Group () Control Code Final Body Weight (g)
Day 12 283 0.007 132
Day 209 417 0.015 213.2
Day 211 381 0.015 360.4
Day 211 447 0.015 300.8
Day 215 304 0.007 331.6
Day 226 418 0.015 237
Day 229 284 0.007 390.7
Day 229 382 0.015 314.8
Day 238 413 0.015 300.4
Day 250 152 0.003 353.1
Day 254 405 0.015 423.8
Day 264 403 0.015 366.6
Day 264 435 0.015 332.4
Day 265 433 0.015 383.8
Day 268 384 0.015 216.2
Day 275 1 0 423.4
Day 275 10 0 438
Day 275 2 0 435.1
Day 275 3 0 455.6
Day 275 4 0 428.9
Day 275 5 0 435.5
Day 275 6 0 446.4
Day 275 7 0 416.9
Day 275 8 0 442.3
Day 275 9 0 414.2
Day 275 383 0.015 386.7
Day 275 385 0.015 358.2
Day 275 386 0.015 343.7
Day 275 387 0.015 344.1
Day 275 388 0.015 289.5
Day 275 389 0.015 338.9
Day 275 390 0.015 370.2
Day 275 391 0.015 332.2
Day 275 392 0.015 343.9
Day 275 393 0.015 342.2
Day 280 397 0.015 306.7
Day 280 415 0.015 376.9
Day 280 432 0.015 379.2
Day 280 450 0.015 343.1
Day 281 410 0.015 302.3
Day 285 237 0.007 445.4
Day 285 252 0.007 385.9
Day 285 264 0.007 397.2
Day 290 424 0.015 311.2
Day 295 297 0.007 362.4
Day 296 412 0.015 237.3
Day 296 426 0.015 327.2
Day 303 421 0.015 240.3
Day 305 429 0.015 202.2
Day 306 449 0.015 220.6
Day 307 288 0.007 287.3
Day 308 406 0.015 202.3
Day 308 416 0.015 276.1
Day 309 400 0.015 339
Day 309 434 0.015 363.6
Day 310 404 0.015 335.4
Day 312 399 0.015 302.5
Day 324 411 0.015 262.4
Day 324 436 0.015 300.3
Day 324 444 0.015 217.7
Day 328 431 0.015 279.1
Day 333 402 0.015 238.1
Day 338 396 0.015 248.8
Day 338 398 0.015 214.6
Day 338 407 0.015 292.9
Day 338 425 0.015 333.2
Day 338 430 0.015 322.7
Day 338 440 0.015 297.1
Day 338 448 0.015 209
Day 341 271 0.007 346.5
Day 343 233 0.007 411.2
Day 343 423 0.015 283.7
Day 343 427 0.015 372.3
Day 344 395 0.015 319
Day 348 422 0.015 203.8
Day 349 445 0.015 192
Day 350 408 0.015 295
Day 350 419 0.015 266
Day 352 401 0.015 289.1
Day 352 409 0.015 350.7
Day 352 420 0.015 338.3
Day 352 438 0.015 344.1
Day 352 439 0.015 336.2
Day 352 442 0.015 276.2
Day 352 443 0.015 342.7
Day 355 278 0.007 302.7
Day 359 145 0.003 394
Day 372 258 0.007 396.6
Day 372 428 0.015 311
Day 372 437 0.015 299.2
Day 372 441 0.015 342.1
Day 378 281 0.007 395.3
Day 379 263 0.007 353.6
Day 379 296 0.007 398.8
Day 379 394 0.015 330.2
Day 383 446 0.015 294.4
Day 384 285 0.007 378.7
Day 384 295 0.007 417.4
Day 384 414 0.015 301.1
Day 391 150 0.003 331.4
Day 391 262 0.007 399.3
Day 393 244 0.007 378.2
Day 404 240 0.007 288
Day 405 179 0.003 338.2
Day 405 289 0.007 412.4
Day 405 292 0.007 386.7
Day 406 269 0.007 374.3
Day 406 275 0.007 357.2
Day 406 305 0.007 356.6
Day 419 11 0 433.6
Day 419 12 0 487.2
Day 419 13 0 449.5
Day 419 14 0 464.8
Day 419 15 0 477.6
Day 419 16 0 434.3
Day 419 17 0 453.3
Day 419 18 0 478.3
Day 419 19 0 488.2
Day 419 20 0 479.6
Day 419 21 0 466.6
Day 419 22 0 469.8
Day 419 24 0 494.3
Day 419 25 0 475.1
Day 419 26 0 526.4
Day 419 141 0.003 502.7
Day 419 142 0.003 430.9
Day 419 143 0.003 391.8
Day 419 144 0.003 459.2
Day 419 146 0.003 446.6
Day 419 147 0.003 470.6
Day 419 148 0.003 453.2
Day 419 149 0.003 415.9
Day 419 151 0.003 474.5
Day 419 153 0.003 480.2
Day 419 231 0.007 431.8
Day 419 232 0.007 406.3
Day 419 234 0.007 390.5
Day 419 235 0.007 400.6
Day 419 236 0.007 449.3
Day 419 238 0.007 423
Day 419 239 0.007 391.6
Day 419 243 0.007 373
Day 419 245 0.007 404.1
Day 419 246 0.007 428.9
Day 419 247 0.007 408.7
Day 419 248 0.007 401.2
Day 419 249 0.007 393.3
Day 419 251 0.007 416.7
Day 419 253 0.007 398.6
Day 420 27 0 439.4
Day 420 28 0 454.6
Day 420 29 0 446.4
Day 420 30 0 498.4
Day 420 31 0 469.9
Day 420 32 0 431.9
Day 420 33 0 446.7
Day 420 34 0 491
Day 420 35 0 451.5
Day 420 36 0 505.5
Day 420 37 0 465.8
Day 420 38 0 455.9
Day 420 39 0 484.3
Day 420 40 0 474
Day 420 41 0 433.8
Day 420 42 0 437.5
Day 420 43 0 464.3
Day 420 44 0 456.1
Day 420 45 0 459.6
Day 420 46 0 436.4
Day 420 154 0.003 454
Day 420 155 0.003 448.5
Day 420 156 0.003 455.5
Day 420 157 0.003 464.5
Day 420 158 0.003 491
Day 420 159 0.003 458.4
Day 420 160 0.003 461.5
Day 420 161 0.003 444.1
Day 420 162 0.003 453.3
Day 420 163 0.003 428.6
Day 420 164 0.003 440.5
Day 420 165 0.003 449.4
Day 420 166 0.003 442.5
Day 420 167 0.003 421.7
Day 420 168 0.003 454.3
Day 420 169 0.003 473.3
Day 420 170 0.003 407.3
Day 420 171 0.003 432.6
Day 420 172 0.003 454.3
Day 420 173 0.003 419.7
Day 420 254 0.007 413
Day 420 255 0.007 399.7
Day 420 256 0.007 431.1
Day 420 257 0.007 414.5
Day 420 259 0.007 318.4
Day 420 260 0.007 447.3
Day 420 261 0.007 381.3
Day 420 265 0.007 416.2
Day 420 266 0.007 423.1
Day 420 267 0.007 434.7
Day 420 268 0.007 348
Day 420 270 0.007 419.9
Day 420 272 0.007 419.8
Day 420 273 0.007 402.7
Day 420 274 0.007 433.7
Day 420 276 0.007 413.2
Day 420 277 0.007 437.1
Day 420 279 0.007 389.3
Day 420 280 0.007 408.8
Day 420 282 0.007 410.3
Day 421 47 0 476.4
Day 421 48 0 471.5
Day 421 49 0 451.7
Day 421 50 0 467.9
Day 421 51 0 452.2
Day 421 52 0 449.2
Day 421 53 0 463.8
Day 421 54 0 446
Day 421 55 0 500.4
Day 421 56 0 459.5
Day 421 57 0 487.2
Day 421 58 0 517.4
Day 421 59 0 442.4
Day 421 60 0 431
Day 421 61 0 457.6
Day 421 62 0 464.2
Day 421 63 0 441.9
Day 421 64 0 454.1
Day 421 65 0 503.9
Day 421 66 0 494.6
Day 421 67 0 493.1
Day 421 68 0 478.9
Day 421 69 0 448.7
Day 421 70 0 453.5
Day 421 174 0.003 456.8
Day 421 175 0.003 499.7
Day 421 176 0.003 487.3
Day 421 177 0.003 455.8
Day 421 178 0.003 436.5
Day 421 180 0.003 479.2
Day 421 182 0.003 362.7
Day 421 183 0.003 435
Day 421 184 0.003 481.9
Day 421 185 0.003 385.4
Day 421 286 0.007 424.3
Day 421 287 0.007 437
Day 421 290 0.007 384.2
Day 421 291 0.007 415.4
Day 421 293 0.007 404.2
Day 421 294 0.007 404.1
Day 421 298 0.007 402.7
Day 421 299 0.007 267.8
Day 421 301 0.007 419.4
Day 421 302 0.007 443.8
Day 421 303 0.007 392.8
Day 425 250 0.007 314.9
Day 426 23 0 437.7
Day 426 181 0.003 414.5
Day 426 241 0.007 427.5
Day 426 242 0.007 335.9
Day 426 300 0.007 371.3
Abbreviations:
NA: Not Available