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Organ Weights Individual Animal

Study Information:

Chemical Name: 50 ppm Wy-14,643; Methapyrilene Hydrochloride
CASRN: ="135-23-9; 50892-23-4"
Study Number: C55550E
Study Length (Year Completed): 13 Weeks (N/A)
Exposure Route: FEED
TDMS Number: 5555001.ss
Sex: Male
Strain and Species: Fischer 344 Rats

Organ Weights Individual Animal Data
Measurement Time Animal Number Dose Group (ppm) Control Code Terminal Body Weight (g) Liver (g)
Day 15 0001 0 U 206.1 9.927
Day 15 0003 0 U 215.4 10.75
Day 15 0004 0 U 195.9 8.754
Day 15 0005 0 U 185.2 7.66
Day 15 0021 0 U 210.4 9.898
Day 15 0022 0 U 209.5 9.866
Day 15 0023 0 U 209.3 9.892
Day 15 0024 0 U 198.6 8.949
Day 15 0025 0 U 190.9 9.047
Day 15 0202 0 P 177.3 16.88
Day 15 0203 0 P 197.2 21.071
Day 15 0205 0 P 183.2 17.902
Day 15 0221 0 P 184.4 15.793
Day 15 0222 0 P 175.1 16.061
Day 15 0223 0 P 192.6 17.192
Day 15 0224 0 P 214.5 19.573
Day 15 0225 0 P 205.3 17.245
Day 15 0241 0 N 196.6 8.866
Day 15 0242 0 N 181 7.786
Day 15 0243 0 N 167.6 7.973
Day 15 0244 0 N 205.6 9.211
Day 15 0245 0 N 176.2 7.945
Day 15 0261 0 N 183.5 8.598
Day 15 0262 0 N 185 8.294
Day 15 0263 0 N 206.8 9.525
Day 15 0264 0 N 212 9.988
Day 15 0265 0 N 193.1 8.334
Day 15 0041 50 192.8 8.962
Day 15 0042 50 193 8.696
Day 15 0043 50 187.2 9.278
Day 15 0044 50 213.8 9.138
Day 15 0045 50 178.7 7.359
Day 15 0061 50 206.4 10.08
Day 15 0062 50 203.5 10.576
Day 15 0063 50 203.8 9.717
Day 15 0064 50 215.2 9.729
Day 15 0065 50 209.9 9.393
Day 15 0081 100 197.1 8.741
Day 15 0082 100 205.9
Day 15 0083 100 191.5 9.855
Day 15 0085 100 180.8 8.117
Day 15 0101 100 214.3 9.858
Day 15 0102 100 220.7 10.432
Day 15 0103 100 202.3 9.122
Day 15 0104 100 234.4 11.375
Day 15 0105 100 211.6 9.823
Day 15 0121 250 173.6 7.383
Day 15 0122 250 215.3 10.132
Day 15 0123 250 176.3 8.614
Day 15 0124 250 187.8 8.382
Day 15 0125 250 199.6 9.157
Day 15 0141 250 218.6 10.411
Day 15 0142 250 201.1 9.683
Day 15 0143 250 187.7 8.644
Day 15 0144 250 215.1 10.651
Day 15 0145 250 200 9.01
Day 15 0161 1000 166.7 9.807
Day 15 0162 1000 152.4 8.108
Day 15 0163 1000 179.5 10.099
Day 15 0164 1000 174.3 8.044
Day 15 0165 1000 165.2 8.66
Day 15 0181 1000 164.9 8.673
Day 15 0182 1000 167.9 8.706
Day 15 0183 1000 168.2 9.181
Day 15 0184 1000 179.6 9.194
Day 15 0185 1000 163.8 8.079
Day 29 0006 0 U 247.3 10.822
Day 29 0007 0 U 252.2 11.53
Day 29 0008 0 U 268.7 11.357
Day 29 0009 0 U 232.2 9.908
Day 29 0010 0 U 237.5 10.054
Day 29 0026 0 U 248.4 9.721
Day 29 0027 0 U 262.3 11.243
Day 29 0028 0 U 261.3 11.127
Day 29 0029 0 U 245.4 9.795
Day 29 0030 0 U 251.5 10.322
Day 29 0206 0 P 222.3 20.214
Day 29 0207 0 P 252.8 23.47
Day 29 0208 0 P 232.2 21.897
Day 29 0209 0 P 260.5 24.162
Day 29 0210 0 P 231.1 22.328
Day 29 0226 0 P 244.2 24.423
Day 29 0227 0 P 220.4 19.055
Day 29 0228 0 P 252.4 22.81
Day 29 0229 0 P 226.7 20.361
Day 29 0230 0 P 220.8 20.408
Day 29 0246 0 N 239.5 10.558
Day 29 0247 0 N 263.5 12.579
Day 29 0248 0 N 244.5 10.737
Day 29 0249 0 N 246.7 9.418
Day 29 0250 0 N 254.7 10.799
Day 29 0266 0 N 260.7 11.036
Day 29 0267 0 N 263.9 10.888
Day 29 0268 0 N 240.8 9.728
Day 29 0269 0 N 237 10.196
Day 29 0270 0 N 239 9.4
Day 29 0046 50 242.7 11.026
Day 29 0047 50 210.3 8.884
Day 29 0048 50 252.7 11.574
Day 29 0049 50 229.3 10.047
Day 29 0050 50 259.8 10.994
Day 29 0066 50 248.3 9.785
Day 29 0067 50 248.8 9.923
Day 29 0068 50 260.5 11.162
Day 29 0069 50 259.7 10.819
Day 29 0070 50 277.8 12.212
Day 29 0086 100 258.1 10.867
Day 29 0087 100 253.6 10.976
Day 29 0088 100 261.7 11.055
Day 29 0089 100 235.9 9.905
Day 29 0090 100 242.1 10.182
Day 29 0106 100 240.8 10.355
Day 29 0107 100 255.3 10.192
Day 29 0108 100 252.2 10.44
Day 29 0109 100 237.9 10.218
Day 29 0110 100 265.9 11.52
Day 29 0126 250 244.4 10.43
Day 29 0127 250 257.8 11.418
Day 29 0128 250 234 10.405
Day 29 0129 250 230.7 9.826
Day 29 0130 250 248.6 10.525
Day 29 0146 250 223.4 9.164
Day 29 0147 250 251.6 11.661
Day 29 0148 250 241 10.729
Day 29 0149 250 249 10.817
Day 29 0150 250 241.5 10.057
Day 29 0166 1000 186.8 8.757
Day 29 0167 1000 219.1 10.693
Day 29 0168 1000 186.3 8.337
Day 29 0169 1000 187.5 9.16
Day 29 0170 1000 197.6 8.711
Day 29 0186 1000 201.3 9.474
Day 29 0187 1000 196 8.817
Day 29 0188 1000 181.8 8.875
Day 29 0189 1000 176.1 8.573
Day 29 0190 1000 188 9.626
Day 43 0011 0 U 291.1 12.028
Day 43 0012 0 U 297.8 12.123
Day 43 0013 0 U 306.3 12.766
Day 43 0014 0 U 267.4 10.201
Day 43 0015 0 U 276.1 11.302
Day 43 0031 0 U 282 11.025
Day 43 0032 0 U 288.6 11.358
Day 43 0033 0 U 276.5 10.471
Day 43 0034 0 U 254.3 10.32
Day 43 0035 0 U 270.4 10.6
Day 43 0211 0 P 256.2 21.71
Day 43 0212 0 P 249.5 19.731
Day 43 0213 0 P 258 21.534
Day 43 0214 0 P 267.7 24.605
Day 43 0215 0 P 260.4 21.917
Day 43 0231 0 P 277.3 24.262
Day 43 0232 0 P 292.7 26.647
Day 43 0233 0 P 250.3 21.768
Day 43 0234 0 P 274.6 24.712
Day 43 0235 0 P 258.8 23.392
Day 43 0251 0 N 276.3 11.124
Day 43 0252 0 N 242.8 9.503
Day 43 0253 0 N 292.1 11.909
Day 43 0254 0 N 290.6 12.156
Day 43 0255 0 N 307.1 12.256
Day 43 0271 0 N 288.6 11.392
Day 43 0272 0 N 280.9 11.242
Day 43 0273 0 N 295.1 12.645
Day 43 0274 0 N 294.2 9.734
Day 43 0275 0 N 264.9 12.823
Day 43 0051 50 268 10.183
Day 43 0052 50 277.6 11.061
Day 43 0053 50 281.6 10.628
Day 43 0054 50 283.4 11.963
Day 43 0055 50 282 11.468
Day 43 0071 50 261.8 10.026
Day 43 0072 50 290.5 10.72
Day 43 0073 50 279.3 11.264
Day 43 0074 50 296.2 11.544
Day 43 0075 50 314.8 12.57
Day 43 0091 100 277.5 10.506
Day 43 0092 100 264.5 10.078
Day 43 0093 100 280.4 11.387
Day 43 0094 100 264.5 10.591
Day 43 0095 100 263.5 9.651
Day 43 0111 100 261.9 10.049
Day 43 0112 100 270.1 10.93
Day 43 0113 100 266.4 10.986
Day 43 0114 100 275.9 10.735
Day 43 0115 100 285 11.156
Day 43 0131 250 293.7 12.447
Day 43 0132 250 288 12.708
Day 43 0133 250 301.5 13.208
Day 43 0134 250 278.5 11.155
Day 43 0135 250 283.5 11.944
Day 43 0151 250 286.7 12.344
Day 43 0152 250 269.8 10.95
Day 43 0153 250 266.2 11.124
Day 43 0154 250 282.9 12.19
Day 43 0155 250 262 10.306
Day 43 0171 1000 202.9 8.685
Day 43 0172 1000 212.8 9.5
Day 43 0173 1000 187.2 8.376
Day 43 0174 1000 213.6 9.54
Day 43 0175 1000 210 10.528
Day 43 0191 1000 184.2 8.478
Day 43 0192 1000 214.7 8.852
Day 43 0193 1000 199.8 9.572
Day 43 0194 1000 185.2 7.835
Day 43 0195 1000 205.6 8.918
Day 92 0016 0 U 383.4 13.965
Day 92 0017 0 U 351 13.237
Day 92 0018 0 U 353.1 12.462
Day 92 0019 0 U 354.5 12.548
Day 92 0020 0 U 347.7 12.787
Day 92 0036 0 U 374.2 12.925
Day 92 0037 0 U 335 12.674
Day 92 0038 0 U 351.8 11.177
Day 92 0039 0 U 336.6 11.903
Day 92 0040 0 U 364.8 12.646
Day 92 0216 0 P 303.3 26.101
Day 92 0217 0 P 297.2 25.262
Day 92 0218 0 P 360.5 33.157
Day 92 0219 0 P 330.3 28.652
Day 92 0220 0 P 321.2 28.154
Day 92 0236 0 P 335.4 29.472
Day 92 0237 0 P 315.4 27.383
Day 92 0238 0 P 286.1 25.655
Day 92 0239 0 P 323.9 28.592
Day 92 0240 0 P 289.2 23.286
Day 92 0256 0 N 334.7 11.551
Day 92 0257 0 N 347.3 12.467
Day 92 0258 0 N 367.2 12.829
Day 92 0259 0 N 351.7 12.574
Day 92 0260 0 N 348.2 13.977
Day 92 0276 0 N 350.5 12.222
Day 92 0277 0 N 359.7 12.41
Day 92 0278 0 N 317 10.671
Day 92 0279 0 N 378.9 13.751
Day 92 0280 0 N 344.9 12.492
Day 92 0056 50 370.8 12.419
Day 92 0057 50 363.3 12.692
Day 92 0058 50 338.6 11.494
Day 92 0059 50 360.6 12.214
Day 92 0060 50 344 11.384
Day 92 0076 50 359.6 11.986
Day 92 0077 50 377.1 13.015
Day 92 0078 50 384 13.343
Day 92 0079 50 385.9 12.922
Day 92 0080 50 348.8 12.088
Day 92 0096 100 346.8 12.169
Day 92 0097 100 335.6 11.649
Day 92 0098 100 378.9 13.447
Day 92 0099 100 396 14.723
Day 92 0100 100 352 12.384
Day 92 0116 100 366.1 12.864
Day 92 0117 100 352.3 13.696
Day 92 0118 100 365.4 12.308
Day 92 0119 100 347.5 11.758
Day 92 0120 100 353.2 12.065
Day 92 0136 250 357.7 12.725
Day 92 0137 250 329.5 12.1
Day 92 0138 250 347 12.646
Day 92 0139 250 355.1 12.335
Day 92 0140 250 344.9 12.037
Day 92 0156 250 345.5 12.477
Day 92 0157 250 376.2 13.94
Day 92 0158 250 385 13.413
Day 92 0159 250 362.3 13.115
Day 92 0160 250 362 12.661
Day 92 0176 1000 264 10.455
Day 92 0177 1000 247.3 10.273
Day 92 0178 1000 247.9 10.575
Day 92 0179 1000 256.1 10.84
Day 92 0180 1000 238.1 9.99
Day 92 0196 1000 235.8 9.665
Day 92 0197 1000 296.7 12.035
Day 92 0198 1000 234.7 9.916
Day 92 0199 1000 259.8 10.981
Day 92 0200 1000 256.6 11.11
Abbreviations:
NA: Not Available, U: Untreated Control, P: Positive Control, N: Negative Control