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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 1,3-Dichloropropene (Telone II)
CASRN: ="542-75-6"
Study Number: C03985
Exposure Route: Gavage
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 50 NA 1_038 113.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 1_042 113.00 1 Osteosarcoma, Metastatic Natural Death
Alimentary System Liver Vehicle Control 50 NA 1_028 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Vehicle Control 50 NA 1_028 113.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
Alimentary System Liver Vehicle Control 50 NA 1_052 113.00 1 Hemangiosarcoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_122 114.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 050.0 MG/KG 50 NA 2_134 114.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver 050.0 MG/KG 50 NA 2_196 114.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 050.0 MG/KG 50 NA 2_118 114.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_124 114.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_144 114.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_168 114.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_178 114.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_200 114.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_206 114.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_248 114.00 1 Sarcoma, Nos, Metastatic Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_298 114.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_224 114.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_296 114.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Stomach 050.0 MG/KG 50 NA 2_116 114.00 1 Squamous Cell Papilloma Scheduled Sacrifice
Alimentary System Stomach 100.0 MG/KG 50 NA 3_268 114.00 1 Squamous Cell Carcinoma Natural Death
Alimentary System Stomach 100.0 MG/KG 50 NA 3_204 114.00 1 Squamous Cell Carcinoma Scheduled Sacrifice
Alimentary System Stomach 100.0 MG/KG 50 NA 3_208 114.00 1 Squamous Cell Papilloma Scheduled Sacrifice
Alimentary System Stomach 100.0 MG/KG 50 NA 3_222 114.00 1 Squamous Cell Papilloma Scheduled Sacrifice
All Others Unspecified Leg Vehicle Control NA NA 1_042 113.00 1 Osteosarcoma Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 1_060 113.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 1_070 113.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_122 114.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_136 114.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_156 114.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_162 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_172 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_174 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_186 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_198 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_264 114.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_278 114.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_202 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_212 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_222 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_224 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_226 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_230 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_266 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Endocrine System Adrenal gland Vehicle Control 50 NA 1_094 113.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Adrenal gland 050.0 MG/KG 50 NA 2_164 114.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Adrenal gland 050.0 MG/KG 50 NA 2_176 114.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 100.0 MG/KG 50 NA 3_224 114.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Pituitary gland Vehicle Control 48 NA 1_050 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Vehicle Control 48 NA 1_052 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Vehicle Control 48 NA 1_070 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Vehicle Control 48 NA 1_088 113.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_196 114.00 1 Chromophobe Adenoma Natural Death
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_108 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_160 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_180 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_186 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_194 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 100.0 MG/KG 41 NA 3_226 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 100.0 MG/KG 41 NA 3_230 114.00 1 Chromophobe Adenoma Scheduled Sacrifice
Genital System Ovary 050.0 MG/KG 50 NA 2_138 114.00 1 Hemangioma Scheduled Sacrifice
Genital System Ovary 100.0 MG/KG 48 NA 3_232 114.00 1 Teratoma, Nos Natural Death
Genital System Ovary 100.0 MG/KG 48 NA 3_278 114.00 1 Hemangioma Natural Death
Genital System Ovary 100.0 MG/KG 48 NA 3_286 114.00 1 Hemangiosarcoma Natural Death
Genital System Ovary 100.0 MG/KG 48 NA 3_220 114.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Genital System Uterus 050.0 MG/KG 50 NA 2_156 114.00 1 Leiomyosarcoma Natural Death
Genital System Uterus 050.0 MG/KG 50 NA 2_186 114.00 1 Hemangioma Scheduled Sacrifice
Genital System Uterus 100.0 MG/KG 49 NA 3_248 114.00 1 Sarcoma, Nos Natural Death
Hematopoietic System Lymph node Vehicle Control 50 NA 1_032 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Lymph node Vehicle Control 50 NA 1_040 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Lymph node 050.0 MG/KG 50 NA 2_156 114.00 1 Leiomyosarcoma, Metastatic Natural Death
Hematopoietic System Lymph node 050.0 MG/KG 50 NA 2_110 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen Vehicle Control 50 NA 1_068 113.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 50 NA 2_110 114.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 50 NA 2_158 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 100.0 MG/KG 50 NA 3_206 114.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 100.0 MG/KG 50 NA 3_258 114.00 1 Hemangiosarcoma Scheduled Sacrifice
Integumentary System Mammary gland Vehicle Control 50 NA 1_058 113.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland Vehicle Control 50 NA 1_096 113.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 050.0 MG/KG 50 NA 2_122 114.00 1 Fibroadenoma Natural Death
Integumentary System Mammary gland 050.0 MG/KG 50 NA 2_196 114.00 1 Adenocarcinoma, Nos Natural Death
Integumentary System Mammary gland 050.0 MG/KG 50 NA 2_108 114.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 100.0 MG/KG 50 NA 3_228 114.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Respiratory System Lung Vehicle Control 50 NA 1_080 113.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Vehicle Control 50 NA 1_084 113.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_196 114.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Respiratory System Lung 050.0 MG/KG 50 NA 2_102 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_144 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_168 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_180 114.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_252 114.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 100.0 MG/KG 50 NA 3_208 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_214 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_222 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_228 114.00 1 Adenocarcinoma, Nos, Metastatic Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_234 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_250 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_254 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_296 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Urinary System Kidney 050.0 MG/KG 50 NA 2_196 114.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_136 114.00 1 Transitional-Cell Carcinoma Natural Death
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_188 114.00 1 Transitional-Cell Carcinoma Natural Death
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_148 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_150 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_152 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_154 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_170 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 050.0 MG/KG NA NA 2_180 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_278 114.00 1 Transitional-Cell Carcinoma Natural Death
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_298 114.00 1 Transitional-Cell Carcinoma Natural Death
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_204 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_210 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_212 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_216 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_220 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_222 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_224 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_226 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_230 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_234 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_242 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_250 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_254 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_256 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_266 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_272 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_276 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_282 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_292 114.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice