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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 1,3-Dichloropropene (Telone II)
CASRN: ="542-75-6"
Study Number: C03985
Exposure Route: Gavage
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 50 NA 1_085 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 NA 1_035 112.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 1_049 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 1_095 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 1_037 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_141 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 050.0 MG/KG 50 NA 2_107 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_123 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_135 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_143 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_161 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 050.0 MG/KG 50 NA 2_193 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_213 113.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_219 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_233 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_269 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_281 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_291 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 100.0 MG/KG 50 NA 3_225 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_237 113.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_273 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_279 113.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_283 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_289 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 100.0 MG/KG 50 NA 3_299 113.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Pancreas Islets Vehicle Control 50 NA 1_017 112.00 1 Islet-Cell Adenoma Natural Death
Alimentary System Stomach 050.0 MG/KG 50 NA 2_137 112.00 1 Squamous Cell Papilloma Natural Death
Alimentary System Stomach 050.0 MG/KG 50 NA 2_139 112.00 1 Squamous Cell Papilloma Scheduled Sacrifice
Alimentary System Stomach 100.0 MG/KG 50 NA 3_211 113.00 1 Squamous Cell Papilloma Natural Death
Alimentary System Stomach 100.0 MG/KG 50 NA 3_251 113.00 1 Squamous Cell Papilloma Natural Death
Alimentary System Stomach 100.0 MG/KG 50 NA 3_239 113.00 1 Squamous Cell Papilloma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_147 112.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 2_197 112.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_219 113.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_217 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 100.0 MG/KG NA NA 3_221 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified 050.0 MG/KG NA NA 2_165 112.00 1 Leiomyosarcoma Natural Death
Endocrine System Adrenal gland Vehicle Control 50 NA 1_049 112.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland 100.0 MG/KG 48 NA 3_223 113.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 100.0 MG/KG 48 NA 3_239 113.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 050.0 MG/KG 48 NA 2_159 112.00 1 Chromophobe Adenoma Scheduled Sacrifice
Hematopoietic System Bone marrow 050.0 MG/KG 49 NA 2_155 112.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Lymph node 050.0 MG/KG 50 NA 2_137 112.00 1 Lymphoma, Nos-Malignant Natural Death
Hematopoietic System Spleen Vehicle Control 50 NA 1_061 112.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_173 112.00 1 Lymphoma, Nos-Malignant Natural Death
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_103 112.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_111 112.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_119 112.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_133 112.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_155 112.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 050.0 MG/KG 49 NA 2_159 112.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Spleen 100.0 MG/KG 49 NA 3_227 113.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 100.0 MG/KG 49 NA 3_235 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 100.0 MG/KG 49 NA 3_283 113.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Thymus 050.0 MG/KG 48 NA 2_189 112.00 1 Hemangiosarcoma Natural Death
Respiratory System Lung Vehicle Control 50 NA 1_051 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 050.0 MG/KG 50 NA 2_113 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 050.0 MG/KG 50 NA 2_141 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 050.0 MG/KG 50 NA 2_157 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 050.0 MG/KG 50 NA 2_177 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 050.0 MG/KG 50 NA 2_103 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_105 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_109 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_123 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_125 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_131 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_135 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_139 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_149 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 050.0 MG/KG 50 NA 2_193 112.00 1 Hepatocellular Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_213 113.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 100.0 MG/KG 50 NA 3_229 113.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 100.0 MG/KG 50 NA 3_233 113.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 100.0 MG/KG 50 NA 3_265 113.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 100.0 MG/KG 50 NA 3_277 113.00 1 Adenocarcinoma Nos Uncertain Primary/Metastatic Natural Death
Respiratory System Lung 100.0 MG/KG 50 NA 3_217 113.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_231 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_235 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_243 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_253 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_273 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_273 113.00 1 Hepatocellular Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_275 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 100.0 MG/KG 50 NA 3_293 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 100.0 MG/KG 50 NA 3_259 113.00 1 Adenoma, Nos Natural Death
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_277 113.00 1 Transitional-Cell Carcinoma Natural Death
Urinary System Urinary bladder 100.0 MG/KG NA NA 3_217 113.00 1 Transitional-Cell Carcinoma Scheduled Sacrifice