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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 2,4-Diaminoanisole sulfate
CASRN: ="39156-41-7"
Study Number: C01989
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Large Colon Untreated Control 40 NA 1_015 103.00 1 Leiomyosarcoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 47 NA 1_010 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 47 NA 1_021 103.00 1 Fibrosarcoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 4_037 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 1200 PPM 42 NA 2_027 104.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 2400 PPM 50 NA 3_014 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 2400 PPM 50 NA 3_046 103.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Alimentary System Liver 2400 PPM 50 NA 3_047 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Stomach Untreated Control 44 NA 1_018 103.00 1 Squamous Cell Papilloma Scheduled Sacrifice
All Others Unspecified Body Cavities 1200 PPM NA NA 2_004 104.00 1 Mesothelioma, Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 1_002 103.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 1_003 103.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 1_040 103.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_044 102.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 4_045 102.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_031 104.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_034 104.00 1 Lymphoma, Undifferentiated-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_011 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_015 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_020 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_025 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1200 PPM NA NA 2_026 104.00 1 Lymphoma, Undifferentiated-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_009 103.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_036 103.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_008 103.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_022 103.00 1 Lymphoma, Undifferentiated-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_030 103.00 1 Lymphoma, Undifferentiated-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_033 103.00 1 Lymphoma, Undifferentiated-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 2400 PPM NA NA 3_042 103.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Untreated Control NA NA 1_021 103.00 1 Leiomyosarcoma Scheduled Sacrifice
All Others Unspecified 2400 PPM NA NA 3_021 103.00 1 Fibrosarcoma Scheduled Sacrifice
Endocrine System Adrenal gland Untreated Control 45 NA 1_039 103.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Adrenal gland 2400 PPM 49 NA 3_016 103.00 1 Cortical Adenoma Moribund Sacrifice
Endocrine System Adrenal gland 2400 PPM 49 NA 3_029 103.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 42 NA 1_024 103.00 1 Carcinoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 42 NA 1_048 103.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 42 NA 1_049 103.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 42 NA 4_015 102.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 42 NA 4_018 102.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 42 NA 4_044 102.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1200 PPM 38 NA 2_019 104.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1200 PPM 38 NA 2_043 104.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1200 PPM 38 NA 2_045 104.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1200 PPM 38 NA 2_046 104.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1200 PPM 38 NA 2_050 104.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 2400 PPM 34 NA 3_002 103.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 2400 PPM 34 NA 3_003 103.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 2400 PPM 34 NA 3_015 103.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 2400 PPM 34 NA 3_018 103.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 2400 PPM 34 NA 3_047 103.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_005 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_017 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_029 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_039 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_041 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_043 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_044 103.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 2400 PPM 45 NA 3_050 103.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Genital System Ovary Untreated Control 45 NA 1_006 103.00 1 Tubular Adenoma Scheduled Sacrifice
Genital System Ovary 1200 PPM 40 NA 2_019 104.00 1 Granulosa-Cell Tumor Scheduled Sacrifice
Genital System Ovary 2400 PPM 43 NA 3_033 103.00 1 Granulosa-Cell Tumor Scheduled Sacrifice
Genital System Uterus Fallopian Tube Untreated Control 48 NA 4_032 102.00 1 Papillary Adenoma Scheduled Sacrifice
Genital System Uterus Untreated Control 45 NA 1_009 103.00 1 Endometrial Stromal Polyp Moribund Sacrifice
Genital System Uterus Untreated Control 45 NA 1_019 103.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus Untreated Control 45 NA 1_029 103.00 1 Leiomyosarcoma Scheduled Sacrifice
Genital System Uterus Untreated Control 45 NA 1_043 103.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1200 PPM 41 NA 2_002 104.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Genital System Uterus 2400 PPM 46 NA 3_032 103.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 1200 PPM 40 NA 2_003 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 1200 PPM 40 NA 2_012 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 2400 PPM 50 NA 3_034 103.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 46 NA 1_033 103.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 46 NA 1_043 103.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 1200 PPM 44 NA 2_006 104.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 1200 PPM 44 NA 2_013 104.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 1200 PPM 44 NA 2_043 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen 1200 PPM 44 NA 2_044 104.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen 1200 PPM 44 NA 2_050 104.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Thymus Untreated Control 31 NA 1_024 103.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Thymus 2400 PPM 32 NA 3_010 103.00 1 Lymphangioma Scheduled Sacrifice
Integumentary System Mammary gland 1200 PPM 2 NA 2_049 104.00 1 Adenocarcinoma, Nos Natural Death
Integumentary System Mammary gland 1200 PPM 2 NA 2_035 104.00 1 Carcinoma, Nos Scheduled Sacrifice
Respiratory System Lung Untreated Control 46 NA 1_012 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 46 NA 1_013 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 46 NA 1_019 103.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 46 NA 1_038 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 4_009 102.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 4_036 102.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 4_042 102.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 1200 PPM 43 NA 2_049 104.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 1200 PPM 43 NA 2_001 104.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 1200 PPM 43 NA 2_019 104.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 1200 PPM 43 NA 2_024 104.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 1200 PPM 43 NA 2_033 104.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 1200 PPM 43 NA 2_035 104.00 1 Carcinoma, Nos, Metastatic Scheduled Sacrifice
Respiratory System Lung 2400 PPM 50 NA 3_028 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 2400 PPM 50 NA 3_031 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 2400 PPM 50 NA 3_040 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 2400 PPM 50 NA 3_041 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 4_023 102.00 1 Papillary Adenoma Scheduled Sacrifice