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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 2-Chloro-p-phenylenediamine sulfate
CASRN: ="61702-44-1"
Study Number: C03316
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Peyers Patch 3000 PPM NA NA 1_032 111.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Alimentary System Liver Untreated Control 19 NA 3_004 114.00 1 Lymphoma, Histiocytic-Malignant Type Moribund Sacrifice
Alimentary System Liver Untreated Control 19 NA 3_007 114.00 1 Leukemia, Undifferentiated Natural Death
Alimentary System Liver Untreated Control 19 NA 3_009 114.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 19 NA 3_020 114.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_028 111.00 1 Neoplasm, Nos Natural Death
Alimentary System Liver 3000 PPM 49 NA 1_011 111.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_015 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_041 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_042 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_049 111.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_030 111.00 1 Hemangiosarcoma Moribund Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_004 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_005 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_009 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_022 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_026 111.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_027 111.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_033 111.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_038 111.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_039 111.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_001 114.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 1_004 111.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 1_007 111.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 1_012 111.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 1_024 111.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 1_003 111.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_012 111.00 1 Lymphoma, Histiocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_001 111.00 1 Leukemia, Undifferentiated Natural Death
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_018 111.00 1 Leukemia, Undifferentiated Natural Death
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_016 111.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_026 111.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_027 111.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 2_050 111.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Untreated Control NA NA 3_014 114.00 1 Fibrosarcoma Scheduled Sacrifice
All Others Unspecified 3000 PPM NA NA 1_036 111.00 1 Sarcoma, Nos Natural Death
All Others Unspecified 3000 PPM NA NA 1_006 111.00 1 Sarcoma, Nos Scheduled Sacrifice
All Others Unspecified 6000 PPM NA NA 2_036 111.00 1 Adenocarcinoma, Nos Moribund Sacrifice
Endocrine System Adrenal gland Capsule 3000 PPM 46 NA 1_037 111.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Adrenal gland 3000 PPM 46 NA 1_047 111.00 1 Cortical Carcinoma Natural Death
Endocrine System Adrenal gland 6000 PPM 41 NA 2_034 111.00 1 Pheochromocytoma Natural Death
Endocrine System Pituitary gland Untreated Control 15 NA 3_019 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 35 NA 1_022 111.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland 3000 PPM 35 NA 1_030 111.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 35 NA 1_033 111.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 35 NA 1_037 111.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 35 NA 1_046 111.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 6000 PPM 24 NA 2_019 111.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_014 114.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_017 114.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 3000 PPM 42 NA 1_024 111.00 1 Follicular-Cell Carcinoma Natural Death
Endocrine System Thyroid 6000 PPM 38 NA 2_045 111.00 1 Neoplasm, Nos Natural Death
Genital System Ovary Untreated Control 17 NA 3_001 114.00 1 Cystadenoma, Nos Scheduled Sacrifice
Genital System Ovary Untreated Control 17 NA 3_019 114.00 1 Cystadenoma, Nos Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_037 111.00 1 Papillary Cystadenoma, Nos Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_048 111.00 1 Sertoli-Cell Tumor Scheduled Sacrifice
Genital System Ovary 6000 PPM 38 NA 2_035 111.00 1 Papillary Cystadenoma, Nos Scheduled Sacrifice
Genital System Uterus Untreated Control 17 NA 3_008 114.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 3000 PPM 47 NA 1_020 111.00 1 Endometrial Stromal Sarcoma Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 3000 PPM 46 NA 1_040 111.00 1 Lymphoma, Nos-Malignant Moribund Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 6000 PPM 43 NA 2_015 111.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Lymph node Untreated Control 17 NA 3_020 114.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 18 NA 3_002 114.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 18 NA 3_009 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 18 NA 3_013 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 18 NA 3_018 114.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 3000 PPM 49 NA 1_018 111.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 6000 PPM 43 NA 2_007 111.00 1 Hemangiosarcoma Moribund Sacrifice
Hematopoietic System Spleen 6000 PPM 43 NA 2_030 111.00 1 Hemangiosarcoma Moribund Sacrifice
Integumentary System Mammary gland Untreated Control 8 NA 3_001 114.00 1 Adenoma, Nos Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 1_033 111.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 1_034 111.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 1_035 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 6000 PPM 44 NA 2_036 111.00 1 Adenocarcinoma, Nos, Metastatic Moribund Sacrifice
Respiratory System Lung 6000 PPM 44 NA 2_035 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 6000 PPM 44 NA 2_039 111.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 3000 PPM NA NA 1_002 111.00 1 Adenoma, Nos Scheduled Sacrifice