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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 2-Chloro-p-phenylenediamine sulfate
CASRN: ="61702-44-1"
Study Number: C03316
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: F344 Rats

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Large Colon 1500 PPM 47 NA 1_034 112.00 1 Mucinous Adenocarcinoma Scheduled Sacrifice
Alimentary System Liver 1500 PPM 49 NA 1_007 112.00 1 Neoplastic Nodule Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 2_016 113.00 1 Neoplastic Nodule Scheduled Sacrifice
Alimentary System Pancreas Islets Untreated Control 20 NA 3_008 114.00 1 Islet-Cell Adenoma Scheduled Sacrifice
Alimentary System Pancreas Islets Untreated Control 20 NA 3_010 114.00 1 Islet-Cell Adenoma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_016 114.00 1 Leukemia, Myelomonocytic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_004 114.00 1 Leukemia, Myelomonocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_009 114.00 1 Leukemia, Myelomonocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1500 PPM NA NA 1_019 112.00 1 Lymphoma, Histiocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 1500 PPM NA NA 1_010 112.00 1 Leukemia, Myelomonocytic Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_017 113.00 1 Lymphoma, Nos-Malignant Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_001 114.00 1 Fibroma Scheduled Sacrifice
All Others Unspecified 1500 PPM NA NA 1_012 112.00 1 Fibroma Scheduled Sacrifice
Endocrine System Adrenal gland Untreated Control 20 NA 3_002 114.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Adrenal gland Untreated Control 20 NA 3_010 114.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Adrenal gland 1500 PPM 47 NA 1_019 112.00 1 Pheochromocytoma Moribund Sacrifice
Endocrine System Adrenal gland 3000 PPM 49 NA 2_030 113.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_006 114.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_007 114.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_015 114.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_016 114.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_001 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_002 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_004 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_008 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_009 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_011 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_012 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_013 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_017 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 20 NA 3_019 114.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_041 112.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_008 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_009 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_013 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_015 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_016 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_018 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_020 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_032 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_044 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_046 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 1500 PPM 42 NA 1_050 112.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_026 113.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_001 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_006 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_015 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_016 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_019 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_020 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_024 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_029 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_032 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_033 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_038 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 46 NA 2_050 113.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 20 NA 3_002 114.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 1500 PPM 44 NA 1_007 112.00 1 C-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 1500 PPM 44 NA 1_029 112.00 1 C-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 1500 PPM 44 NA 1_050 112.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 3000 PPM 39 NA 2_002 113.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 3000 PPM 39 NA 2_016 113.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid 3000 PPM 39 NA 2_037 113.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Genital System Clitoral gland 1500 PPM NA NA 1_013 112.00 1 Adenoma, Nos Scheduled Sacrifice
Genital System Ovary 1500 PPM 48 NA 1_020 112.00 1 Granulosa-Cell Tumor Scheduled Sacrifice
Genital System Uterus Untreated Control 20 NA 3_007 114.00 1 Endometrial Stromal Polyp Moribund Sacrifice
Genital System Uterus Untreated Control 20 NA 3_016 114.00 1 Adenocarcinoma, Nos Moribund Sacrifice
Genital System Uterus Untreated Control 20 NA 3_002 114.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus Untreated Control 20 NA 3_005 114.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus Untreated Control 20 NA 3_008 114.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1500 PPM 48 NA 1_009 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1500 PPM 48 NA 1_015 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1500 PPM 48 NA 1_030 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1500 PPM 48 NA 1_036 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1500 PPM 48 NA 1_042 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 1500 PPM 48 NA 1_047 112.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 3000 PPM 49 NA 2_002 113.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Genital System Uterus 3000 PPM 49 NA 2_011 113.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland Untreated Control 9 NA 3_006 114.00 1 Fibroadenoma Moribund Sacrifice
Integumentary System Mammary gland Untreated Control 9 NA 3_015 114.00 1 Adenocarcinoma, Nos Moribund Sacrifice
Integumentary System Mammary gland Untreated Control 9 NA 3_004 114.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland Untreated Control 9 NA 3_020 114.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 1500 PPM 21 NA 1_025 112.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 1500 PPM 21 NA 1_043 112.00 1 Adenoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 3000 PPM 14 NA 2_033 113.00 1 Adenoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 3000 PPM 14 NA 2_037 113.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Mammary gland 3000 PPM 14 NA 2_043 113.00 1 Fibroadenoma Scheduled Sacrifice
Integumentary System Zymbal gland Untreated Control NA NA 3_004 114.00 1 Squamous Cell Carcinoma Scheduled Sacrifice
Musculoskeletal System Bone Pelvic Bones Untreated Control NA NA 3_007 114.00 1 Osteosarcoma Moribund Sacrifice
Nervous System Brain 1500 PPM 48 NA 1_039 112.00 1 Astrocytoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 20 NA 3_016 114.00 1 Adenocarcinoma, Nos, Metastatic Moribund Sacrifice
Respiratory System Lung Untreated Control 20 NA 3_004 114.00 1 Squamous Cell Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung Untreated Control 20 NA 3_008 114.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 1500 PPM 49 NA 1_046 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 2_032 113.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_004 114.00 1 Carcinoma, Nos Scheduled Sacrifice
Urinary System Kidney Untreated Control 20 NA 3_016 114.00 1 Adenocarcinoma, Nos, Metastatic Moribund Sacrifice
Urinary System Urinary bladder 1500 PPM NA NA 1_017 112.00 1 Transitional-Cell Carcinoma Natural Death