If this is the first time you are viewing this file, please choose 'Save As' from the 'File' menu and resave this file as an Excel file type. This will greatly speed up future viewings of this file.

Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: 4-Chloro-o-phenylenediamine
CASRN: ="95-83-0"
Study Number: C03292
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 50 NA 3_002 103.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 50 NA 3_044 103.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 50 NA 3_001 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_004 103.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_005 103.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_008 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_009 103.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_015 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_017 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_025 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_029 103.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_033 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_039 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_040 103.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_041 103.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_042 103.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_006 101.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 10000 PPM 49 NA 1_027 101.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 10000 PPM 49 NA 1_002 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_004 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_005 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_008 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_014 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_015 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_019 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_020 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_021 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_022 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_024 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_025 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_026 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_029 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_032 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_033 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_034 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_035 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_036 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_037 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_040 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_041 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_042 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_043 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_047 101.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10000 PPM 49 NA 1_048 101.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_012 102.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_032 102.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_003 102.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 20000 PPM 47 NA 2_018 102.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 20000 PPM 47 NA 2_001 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_004 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_005 102.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_006 102.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_007 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_008 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_015 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_017 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_021 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_022 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_023 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_024 102.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_025 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_026 102.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_027 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_030 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_031 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_034 102.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_035 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_037 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_038 102.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_040 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_041 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_042 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_043 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_045 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_047 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_048 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_049 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 20000 PPM 47 NA 2_050 102.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_010 103.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_045 101.00 1 Lymphoma, Undifferentiated-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_007 101.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_008 101.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10000 PPM NA NA 1_039 101.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 20000 PPM NA NA 2_032 102.00 1 Lymphoma, Undifferentiated-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 20000 PPM NA NA 2_005 102.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 20000 PPM NA NA 2_027 102.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Tail 20000 PPM NA NA 2_014 102.00 1 Leiomyosarcoma Scheduled Sacrifice
Endocrine System Adrenal gland 10000 PPM 45 NA 1_030 101.00 1 Pheochromocytoma Natural Death
Endocrine System Thyroid Untreated Control 39 NA 3_005 103.00 1 Follicular-Cell Carcinoma Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 39 NA 3_045 103.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 10000 PPM 46 NA 1_019 101.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 10000 PPM 46 NA 1_041 101.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 20000 PPM 41 NA 2_021 102.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 20000 PPM 41 NA 2_027 102.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 20000 PPM 41 NA 2_031 102.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Genital System Testis Untreated Control 50 NA 3_049 103.00 1 Embryonal Carcinoma Scheduled Sacrifice
Genital System Testis 20000 PPM 46 NA 2_011 102.00 1 Interstitial-Cell Tumor Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node Untreated Control 49 NA 3_005 103.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node Untreated Control 49 NA 3_045 103.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 50 NA 3_044 103.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen Untreated Control 50 NA 3_050 103.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen Untreated Control 50 NA 3_008 103.00 1 Hemangioma Scheduled Sacrifice
Hematopoietic System Spleen 10000 PPM 47 NA 1_002 101.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 10000 PPM 47 NA 1_042 101.00 1 Sarcoma, Nos Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_001 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_005 103.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_015 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_020 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_022 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_039 103.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_045 103.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_013 101.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 10000 PPM 48 NA 1_001 101.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_003 101.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_009 101.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_014 101.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_026 101.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_033 101.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_038 101.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10000 PPM 48 NA 1_039 101.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_012 102.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_003 102.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung 20000 PPM 47 NA 2_004 102.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_017 102.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_026 102.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_029 102.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_040 102.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 20000 PPM 47 NA 2_046 102.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_001 103.00 1 Cystadenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10000 PPM NA NA 1_008 101.00 1 Papillary Adenoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10000 PPM NA NA 1_014 101.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 20000 PPM NA NA 2_009 102.00 1 Papillary Adenoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 20000 PPM NA NA 2_050 102.00 1 Papillary Cystadenoma, Nos Scheduled Sacrifice