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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Bisphenol A
CASRN: ="80-05-7"
Study Number: C50635
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Duodenum 1000 PPM 5 NA 2_003 112.00 1 Adenomatous Polyp, Nos Scheduled Sacrifice
Alimentary System Intestine Small Jejunum 1000 PPM 40 NA 2_050 112.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Alimentary System Intestine Small Peyers Patch 1000 PPM NA NA 2_017 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Alimentary System Intestine Small Peyers Patch 5000 PPM NA NA 1_039 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_026 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_039 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_001 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 49 NA 3_003 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_015 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_016 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_018 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_022 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_027 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_028 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_030 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_031 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_032 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_036 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_044 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_048 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_022 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_027 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_030 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_043 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_037 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 1000 PPM 49 NA 2_006 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_015 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_017 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_028 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_036 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_040 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_042 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_047 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 1000 PPM 49 NA 2_050 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_021 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 5000 PPM 50 NA 1_027 112.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver 5000 PPM 50 NA 1_033 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 5000 PPM 50 NA 1_001 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_010 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_020 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_022 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_026 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_030 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_035 112.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 5000 PPM 50 NA 1_045 112.00 1 Hepatocellular Adenoma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_026 112.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 1000 PPM NA NA 2_018 112.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 1000 PPM NA NA 2_024 112.00 1 Leukemia, Lymphocytic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 1000 PPM NA NA 2_012 112.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 1000 PPM NA NA 2_002 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1000 PPM NA NA 2_033 112.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 1000 PPM NA NA 2_039 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 1_015 112.00 1 Leukemia, Nos Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 1_017 112.00 1 Leukemia, Nos Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 1_033 112.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 1_047 112.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 5000 PPM NA NA 1_003 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Untreated Control NA NA 3_033 112.00 1 Rhabdomyosarcoma Moribund Sacrifice
Endocrine System Adrenal gland Untreated Control 46 NA 3_023 112.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 1000 PPM 49 NA 2_005 112.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 5000 PPM 48 NA 1_005 112.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 5000 PPM 48 NA 1_046 112.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Adrenal gland 5000 PPM 48 NA 1_050 112.00 1 Sarcoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 5000 PPM 42 NA 1_036 112.00 1 Chromophobe Carcinoma Moribund Sacrifice
Endocrine System Pituitary gland 5000 PPM 42 NA 1_017 112.00 1 Chromophobe Carcinoma Natural Death
Endocrine System Pituitary gland 5000 PPM 42 NA 1_038 112.00 1 Chromophobe Carcinoma Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node Untreated Control 48 NA 3_031 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 1000 PPM 48 NA 2_016 112.00 1 Lymphoma, Mixed-Malignant Type Natural Death
Hematopoietic System Lymph node Mesenteric Lymph Node 1000 PPM 48 NA 2_031 112.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen 5000 PPM 48 NA 1_027 112.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 5000 PPM 48 NA 1_006 112.00 1 Hemangioma Scheduled Sacrifice
Integumentary System Skin Untreated Control 49 NA 3_010 112.00 1 Rhabdomyosarcoma Scheduled Sacrifice
Integumentary System Skin Untreated Control 49 NA 3_032 112.00 1 Fibrosarcoma Scheduled Sacrifice
Integumentary System Zymbal gland 5000 PPM NA NA 1_036 112.00 1 Sebaceous Adenocarcinoma Moribund Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_033 112.00 1 Osteosarcoma, Metastatic Moribund Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_001 112.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung Untreated Control 48 NA 3_003 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_011 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_015 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_015 112.00 1 Hepatocellular Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_022 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_027 112.00 1 Hepatocellular Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_028 112.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_042 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 48 NA 3_048 112.00 1 Hepatocellular Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung 1000 PPM 49 NA 2_027 112.00 1 Hepatocellular Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 1000 PPM 49 NA 2_043 112.00 1 Hepatocellular Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 1000 PPM 49 NA 2_010 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 1000 PPM 49 NA 2_028 112.00 1 Hepatocellular Carcinoma, Metastatic Scheduled Sacrifice
Respiratory System Lung 1000 PPM 49 NA 2_036 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 1000 PPM 49 NA 2_049 112.00 1 Carcinoma, Nos, Uncertain Primary Or Metastatic Scheduled Sacrifice
Respiratory System Lung 5000 PPM 50 NA 1_036 112.00 1 Sebaceous Adenocarcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 5000 PPM 50 NA 1_047 112.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 5000 PPM 50 NA 1_011 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 5000 PPM 50 NA 1_020 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 5000 PPM 50 NA 1_034 112.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Special Senses System Ear External Ear Untreated Control 50 NA 3_002 112.00 1 Hemangioma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland Untreated Control 50 NA 3_031 112.00 1 Papillary Adenoma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 1000 PPM 50 NA 2_011 112.00 1 Papillary Adenoma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 1000 PPM 50 NA 2_014 112.00 1 Papillary Adenoma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 5000 PPM 50 NA 1_038 112.00 1 Papillary Adenoma Scheduled Sacrifice
Urinary System Kidney Untreated Control 49 NA 3_009 112.00 1 Tubular-Cell Adenoma Scheduled Sacrifice