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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: C.I. Acid orange 10
CASRN: ="1936-15-8"
Study Number: C53838
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Mesentery Nos Untreated Control NA NA 3_032 110.00 1 Hemangioma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_012 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_018 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_025 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_025 110.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Alimentary System Liver 3000 PPM 50 NA 2_023 110.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 3000 PPM 50 NA 2_007 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 3000 PPM 50 NA 2_018 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Alimentary System Liver 3000 PPM 50 NA 2_031 110.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 49 NA 1_022 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 49 NA 1_027 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 6000 PPM 49 NA 1_032 110.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Stomach Untreated Control 50 NA 3_015 110.00 1 Osteosarcoma Natural Death
All Others Unspecified Mediastinum Nos Untreated Control NA NA 3_024 110.00 1 Sarcoma, Nos, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_028 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_031 110.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_049 110.00 1 Leukemia, Lymphocytic Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_050 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_021 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_035 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_038 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_041 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_024 110.00 1 Leukemia, Lymphocytic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_041 110.00 1 Lymphoma, Nos-Malignant Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_004 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_006 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_037 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_044 110.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_030 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_034 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_036 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_040 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 2_046 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_005 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_019 110.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_004 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_008 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_016 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_023 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_026 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 6000 PPM NA NA 1_044 110.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Untreated Control NA NA 3_024 110.00 1 Sarcoma, Nos Natural Death
All Others Unspecified 3000 PPM NA NA 2_020 110.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 3000 PPM NA NA 2_045 110.00 1 Fibrosarcoma Scheduled Sacrifice
All Others Unspecified 6000 PPM NA NA 1_011 110.00 1 Fibrosarcoma Natural Death
Endocrine System Adrenal gland 6000 PPM 47 NA 1_047 110.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Parathyroid gland 6000 PPM 25 NA 1_010 110.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 47 NA 3_010 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 47 NA 3_011 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 47 NA 3_025 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 42 NA 2_028 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 42 NA 2_038 110.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 42 NA 2_040 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 42 NA 2_045 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 3000 PPM 42 NA 2_046 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 6000 PPM 41 NA 1_007 110.00 1 Chromophobe Adenoma Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 49 NA 3_032 110.00 1 Follicular-Cell Adenoma Moribund Sacrifice
Endocrine System Thyroid 3000 PPM 45 NA 2_042 110.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Genital System Ovary Untreated Control 44 NA 3_040 110.00 1 Hemangioma Scheduled Sacrifice
Genital System Ovary Untreated Control 44 NA 3_043 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Genital System Ovary 3000 PPM 48 NA 2_005 110.00 1 Hemangioma Natural Death
Genital System Ovary 6000 PPM 42 NA 1_016 110.00 1 Papillary Cystadenoma, Nos Scheduled Sacrifice
Genital System Uterus Untreated Control 48 NA 3_026 110.00 1 Leiomyoma Scheduled Sacrifice
Genital System Uterus Untreated Control 48 NA 3_037 110.00 1 Hemangioma Scheduled Sacrifice
Genital System Uterus 3000 PPM 50 NA 2_010 110.00 1 Hemangioma Scheduled Sacrifice
Genital System Uterus 3000 PPM 50 NA 2_050 110.00 1 Leiomyoma Scheduled Sacrifice
Genital System Uterus 6000 PPM 48 NA 1_010 110.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus 6000 PPM 48 NA 1_027 110.00 1 Hemangioma Scheduled Sacrifice
Genital System Uterus 6000 PPM 48 NA 1_038 110.00 1 Leiomyosarcoma Scheduled Sacrifice
Genital System Uterus 6000 PPM 48 NA 1_039 110.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Hematopoietic System Lymph node Lumbar Lymph Node 6000 PPM 41 NA 1_037 110.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Lymph node Thoracic Lymph Node 6000 PPM 41 NA 1_011 110.00 1 Fibrosarcoma, Metastatic Natural Death
Hematopoietic System Lymph node 3000 PPM 38 NA 2_010 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Hematopoietic System Spleen 3000 PPM 50 NA 2_034 110.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Spleen 6000 PPM 49 NA 1_024 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice
Integumentary System Mammary gland Untreated Control 35 NA 3_023 110.00 1 Adenoma, Nos Natural Death
Integumentary System Mammary gland Untreated Control 35 NA 3_024 110.00 1 Adenoma, Nos Natural Death
Integumentary System Mammary gland Untreated Control 35 NA 3_021 110.00 1 Adenoma, Nos Scheduled Sacrifice
Integumentary System Mammary gland 3000 PPM 40 NA 2_006 110.00 1 Adenoma, Nos Natural Death
Integumentary System Mammary gland 3000 PPM 40 NA 2_013 110.00 1 Adenocarcinoma, Nos Natural Death
Integumentary System Mammary gland 3000 PPM 40 NA 2_008 110.00 1 Adenoma, Nos Scheduled Sacrifice
Integumentary System Skin Untreated Control 49 NA 3_018 110.00 1 Hemangiosarcoma Scheduled Sacrifice
Musculoskeletal System Bone Vertebra Untreated Control NA NA 3_024 110.00 1 Sarcoma, Nos, Invasive Natural Death
Respiratory System Lung Untreated Control 50 NA 3_024 110.00 1 Sarcoma, Nos, Metastatic Natural Death
Respiratory System Lung Untreated Control 50 NA 3_013 110.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_045 110.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 3000 PPM 50 NA 2_020 110.00 1 Fibrosarcoma, Metastatic Moribund Sacrifice
Respiratory System Lung 3000 PPM 50 NA 2_013 110.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Respiratory System Lung 3000 PPM 50 NA 2_016 110.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 6000 PPM 49 NA 1_011 110.00 1 Fibrosarcoma, Metastatic Natural Death
Special Senses System Eye Lacrimal Gland Untreated Control 50 NA 3_029 110.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland Untreated Control 50 NA 3_044 110.00 1 Papillary Adenoma Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 3000 PPM 50 NA 2_009 110.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 6000 PPM 50 NA 1_007 110.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Eye Lacrimal Gland 6000 PPM 50 NA 1_010 110.00 1 Adenoma, Nos Scheduled Sacrifice
Urinary System Kidney 3000 PPM 50 NA 2_018 110.00 1 Tubular-Cell Adenocarcinoma Scheduled Sacrifice
Urinary System Kidney 3000 PPM 50 NA 2_038 110.00 1 Lymphoma, Nos-Malignant Scheduled Sacrifice