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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Chlorpheniramine maleate
CASRN: ="113-92-8"
Study Number: C55265
Exposure Route: Gavage
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Mesentery Nos 050.0 MG/KG NA NA 1_547 113.00 1 Hemangioma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_508 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_509 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_536 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_548 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_506 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_516 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_519 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_522 113.00 1 Hemangioma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_522 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_526 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_529 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_530 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_531 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_532 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_533 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_534 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_545 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_528 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 025.0 MG/KG 49 NA 2_550 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 025.0 MG/KG 49 NA 2_503 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_504 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_507 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_512 113.00 1 Fibrosarcoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_513 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_517 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_518 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_521 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_529 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_531 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_532 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_535 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_536 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_539 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_540 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_541 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_542 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 025.0 MG/KG 49 NA 2_548 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_534 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_535 113.00 1 Hemangiosarcoma Moribund Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_550 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_526 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 050.0 MG/KG 49 NA 1_538 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 050.0 MG/KG 49 NA 1_539 113.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 050.0 MG/KG 49 NA 1_503 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_509 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_530 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 050.0 MG/KG 49 NA 1_541 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 NA 3_536 113.00 1 Squamous Cell Carcinoma Moribund Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 NA 3_533 113.00 1 Squamous Cell Papilloma Terminal Sacrifice
All Others Unspecified Abdomen Vehicle Control NA NA 3_512 113.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Abdomen 050.0 MG/KG NA NA 1_539 113.00 1 Fibrosarcoma Natural Death
All Others Unspecified Back Vehicle Control NA NA 3_540 113.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Back 025.0 MG/KG NA NA 2_524 113.00 1 Fibrosarcoma Natural Death
All Others Unspecified Back 025.0 MG/KG NA NA 2_516 113.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Back 025.0 MG/KG NA NA 2_518 113.00 1 Fibroma Terminal Sacrifice
All Others Unspecified Back 050.0 MG/KG NA NA 1_525 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Back 050.0 MG/KG NA NA 1_534 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Flank Vehicle Control NA NA 3_546 113.00 1 Sarcoma, Nos Natural Death
All Others Unspecified Groin 050.0 MG/KG NA NA 1_532 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Hip 050.0 MG/KG NA NA 1_535 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Leg Vehicle Control NA NA 3_546 113.00 1 Fibrosarcoma Natural Death
All Others Unspecified Leg 050.0 MG/KG NA NA 1_550 113.00 1 Neurofibrosarcoma Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_514 113.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_503 113.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_513 113.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_502 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_504 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_529 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_542 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_547 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_509 113.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_528 113.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_537 113.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_504 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_525 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_527 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_534 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 025.0 MG/KG NA NA 2_540 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 1_524 113.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 1_506 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 1_520 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 050.0 MG/KG NA NA 1_545 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Shoulder Vehicle Control NA NA 3_539 113.00 1 Fibroma Terminal Sacrifice
All Others Unspecified Shoulder 050.0 MG/KG NA NA 1_546 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Thorax 025.0 MG/KG NA NA 2_519 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Thorax 025.0 MG/KG NA NA 2_511 113.00 1 Neurofibrosarcoma Natural Death
All Others Unspecified 050.0 MG/KG NA NA 1_524 113.00 1 Sarcoma, Nos Moribund Sacrifice
Endocrine System Adrenal gland Capsule Vehicle Control 50 NA 3_530 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule Vehicle Control 50 NA 3_541 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_509 113.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_503 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_514 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_520 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_523 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_530 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 025.0 MG/KG 49 NA 2_531 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 050.0 MG/KG 49 NA 1_506 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 050.0 MG/KG 49 NA 1_520 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 050.0 MG/KG 49 NA 1_543 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Capsule 050.0 MG/KG 49 NA 1_545 113.00 1 Adenoma, Nos Terminal Sacrifice
Endocrine System Adrenal gland Medulla 025.0 MG/KG 49 NA 2_527 113.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland 050.0 MG/KG 49 NA 1_524 113.00 1 Cortical Adenoma Moribund Sacrifice
Endocrine System Thyroid Vehicle Control 50 NA 3_525 113.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Endocrine System Thyroid Vehicle Control 50 NA 3_549 113.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Endocrine System Thyroid 025.0 MG/KG 49 NA 2_540 113.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Genital System Epididymis 025.0 MG/KG 49 NA 2_522 113.00 1 Lipoma Natural Death
Genital System Epididymis 025.0 MG/KG 49 NA 2_542 113.00 1 Adenoma, Nos Terminal Sacrifice
Genital System Testis Vehicle Control 50 NA 3_520 113.00 1 Interstitial-Cell Tumor Terminal Sacrifice
Genital System Testis 025.0 MG/KG 49 NA 2_513 113.00 1 Interstitial-Cell Tumor Terminal Sacrifice
Genital System Testis 025.0 MG/KG 49 NA 2_531 113.00 1 Interstitial-Cell Tumor Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 025.0 MG/KG 49 NA 2_504 113.00 1 Hemangiosarcoma Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 49 NA 3_510 113.00 1 Lymphoma, Undifferentiated-Malignant Type Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_508 113.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_536 113.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_548 113.00 1 Hepatocellular Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_546 113.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_546 113.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_507 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_511 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_511 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_512 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_516 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_517 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_522 113.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_523 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_527 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_528 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_529 113.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_530 113.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_531 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_532 113.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_533 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_539 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_547 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_549 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 025.0 MG/KG 49 NA 2_519 113.00 1 Fibrosarcoma, Metastatic Moribund Sacrifice
Respiratory System Lung 025.0 MG/KG 49 NA 2_511 113.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 025.0 MG/KG 49 NA 2_524 113.00 1 Fibrosarcoma, Metastatic Natural Death
Respiratory System Lung 025.0 MG/KG 49 NA 2_528 113.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 025.0 MG/KG 49 NA 2_503 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 025.0 MG/KG 49 NA 2_516 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 025.0 MG/KG 49 NA 2_535 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 050.0 MG/KG 48 NA 1_550 113.00 1 Neurofibrosarcoma, Metastatic Moribund Sacrifice
Respiratory System Lung 050.0 MG/KG 48 NA 1_526 113.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung 050.0 MG/KG 48 NA 1_538 113.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung 050.0 MG/KG 48 NA 1_543 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 050.0 MG/KG 48 NA 1_545 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 050.0 MG/KG 48 NA 1_547 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Trachea Peritracheal Tissue 025.0 MG/KG NA NA 2_511 113.00 1 Neurofibrosarcoma, Invasive Natural Death
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_548 113.00 1 Adenoma, Nos Moribund Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_502 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_511 113.00 1 Adenocarcinoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_527 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_531 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_542 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_550 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 025.0 MG/KG NA NA 2_501 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 025.0 MG/KG NA NA 2_503 113.00 1 Adenocarcinoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 025.0 MG/KG NA NA 2_505 113.00 1 Adenocarcinoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 025.0 MG/KG NA NA 2_525 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 050.0 MG/KG NA NA 1_512 113.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 050.0 MG/KG NA NA 1_547 113.00 1 Adenoma, Nos Terminal Sacrifice
Urinary System Kidney 025.0 MG/KG 49 NA 2_541 113.00 1 Tubular-Cell Adenoma Terminal Sacrifice
Urinary System Kidney 050.0 MG/KG 49 NA 1_539 113.00 1 Fibrosarcoma, Metastatic Natural Death
Urinary System Kidney 050.0 MG/KG 49 NA 1_548 113.00 1 Tubular-Cell Adenocarcinoma Terminal Sacrifice