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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: HC yellow 4
CASRN: ="59820-43-8"
Study Number: C56019
Exposure Route: DOSED FEED
TDMS Number: 0505702
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Gallbladder Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Intestine Large Colon Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Intestine Large Rectum 1. % 50 36 180 731 1 Adenocarcinoma Terminal Sacrifice
Alimentary System Intestine Small Ileum Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Alimentary System Intestine Small Ileum Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Intestine Small Ileum 0.5 % 18 26 127 736 1 Lymphoma Malignant Undifferentiated Cell Type Terminal Sacrifice
Alimentary System Intestine Small Ileum 1. % 50 35 171 730 1 Lymphoma Malignant Undifferentiated Cell Type Terminal Sacrifice
Alimentary System Intestine Small Jejunum Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Liver Untreated Control 50 11 54 734 1 Hemangioma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 4 16 519 1 Hemangiosarcoma Dead
Alimentary System Liver Untreated Control 50 7 34 721 Multiple Hemangiosarcoma Dead
Alimentary System Liver Untreated Control 50 10 48 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 11 54 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 13 63 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 14 66 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 14 67 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 14 70 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 2 8 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 8 39 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 0.5 % 22 16 76 626 1 Hepatocellular Adenoma Moribund
Alimentary System Liver 0.5 % 22 18 89 512 1 Hepatocellular Adenoma Moribund
Alimentary System Liver 0.5 % 22 23 113 567 1 Hepatocellular Adenoma Moribund
Alimentary System Liver 0.5 % 22 16 78 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 0.5 % 22 19 93 735 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 0.5 % 22 24 116 736 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 0.5 % 22 28 138 736 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 1. % 50 29 143 730 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 1. % 50 31 153 730 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 1. % 50 37 184 731 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 1. % 50 42 206 731 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 12 59 694 1 Hepatocellular Carcinoma Moribund
Alimentary System Liver Untreated Control 50 6 30 723 Multiple Hepatocellular Carcinoma Moribund
Alimentary System Liver Untreated Control 50 1 5 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 2 10 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 6 26 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 0.5 % 22 18 89 512 Multiple Hepatocellular Carcinoma Moribund
Alimentary System Liver 0.5 % 22 18 90 592 1 Hepatocellular Carcinoma Moribund
Alimentary System Liver 0.5 % 22 23 113 567 Multiple Hepatocellular Carcinoma Moribund
Alimentary System Liver 0.5 % 22 26 129 607 1 Hepatocellular Carcinoma Moribund
Alimentary System Liver 0.5 % 22 28 136 675 1 Hepatocellular Carcinoma Moribund
Alimentary System Liver 0.5 % 22 16 78 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 0.5 % 22 19 93 735 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 30 150 617 Multiple Hepatocellular Carcinoma Moribund
Alimentary System Liver 1. % 50 29 143 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 29 144 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 31 151 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 31 152 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 32 159 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 33 165 730 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 35 175 731 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 1. % 50 36 180 731 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 10 48 734 1 Lipoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Alimentary System Liver Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Mesentery Untreated Control 3 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Mesentery 1. % 2 40 199 448 1 Sarcoma Moribund
Alimentary System Pancreas Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Salivary Glands Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Alimentary System Stomach Forestomach Untreated Control 50 10 48 734 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach Untreated Control 50 6 26 734 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach Untreated Control 50 9 44 734 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach 0.5 % 20 19 94 734 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach 0.5 % 20 24 119 736 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach 1. % 50 31 153 730 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Glandular Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Alimentary System Stomach Glandular Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Cardiovascular System Heart Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Minimal Moribund
Cardiovascular System Heart 0.5 % 17 16 76 626 1 Sarcoma Metastatic Moribund
Endocrine System Adrenal Gland Cortex Untreated Control 50 13 63 734 Multiple Adenoma Terminal Sacrifice
Endocrine System Adrenal Gland Cortex Untreated Control 50 9 43 734 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel Untreated Control 50 5 23 508 1 Adenoma Moribund
Endocrine System Thyroid Gland Follicular Cel 1. % 50 35 175 731 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel 1. % 50 36 180 731 1 Adenoma Terminal Sacrifice
Genital System Epididymis Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Genital System Preputial Gland Untreated Control 9 6 30 723 1 Fibrosarcoma Moribund
Genital System Prostate Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Genital System Testes Untreated Control 50 2 8 734 1 Sertoli Cell Tumor Benign Terminal Sacrifice
Hematopoietic System Bone Marrow Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Hematopoietic System Lymph Node Lumbar Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Hematopoietic System Lymph Node Mandibular Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Hematopoietic System Lymph Node Mediastinal Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Hematopoietic System Lymph Node Mediastinal, Pancreatic 0.5 % 31 16 76 626 1 Sarcoma Metastatic Moribund
Hematopoietic System Lymph Node Mesenteric Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Hematopoietic System Lymph Node Mesenteric 0.5 % 31 26 127 736 1 Lymphoma Malignant Undifferentiated Cell Type Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 1. % 50 35 171 730 1 Lymphoma Malignant Undifferentiated Cell Type Terminal Sacrifice
Hematopoietic System Lymph Node Pancreatic Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Hematopoietic System Spleen Untreated Control 50 4 16 519 1 Hemangiosarcoma Dead
Hematopoietic System Spleen Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Hematopoietic System Spleen Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Hematopoietic System Spleen 0.5 % 23 26 127 736 1 Lymphoma Malignant Undifferentiated Cell Type Terminal Sacrifice
Hematopoietic System Spleen 1. % 50 35 171 730 1 Lymphoma Malignant Undifferentiated Cell Type Terminal Sacrifice
Hematopoietic System Thymus Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Integumentary System Skin Subcut Tiss 0.5 % 33 22 107 735 1 Fibroma Terminal Sacrifice
Integumentary System Skin Subcut Tiss Untreated Control 50 5 23 508 1 Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss Untreated Control 50 6 30 723 Multiple Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss Untreated Control 50 8 38 723 1 Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss Untreated Control 50 9 45 723 1 Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss Untreated Control 50 11 53 734 1 Fibrosarcoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss Untreated Control 50 14 66 734 1 Fibrosarcoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 0.5 % 33 24 117 291 1 Fibrosarcoma Dead
Integumentary System Skin Subcut Tiss 0.5 % 33 28 139 384 1 Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss 1. % 50 32 156 484 1 Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss 1. % 50 37 182 679 1 Fibrosarcoma Moribund
Integumentary System Skin Subcut Tiss 1. % 50 42 207 567 1 Fibrosarcoma Moribund
Integumentary System Skin 1. % 50 36 177 701 1 Squamous Cell Carcinoma Moribund
Musculoskeletal System Skeletal Muscle 0.5 % 1 16 76 626 1 Sarcoma Moribund
Nervous System Brain 0.5 % 18 19 91 735 1 Meningioma Benign Terminal Sacrifice
Respiratory System Lung Untreated Control 50 7 34 721 1 Alveolar/Bronchiolar Adenoma Dead
Respiratory System Lung Untreated Control 50 6 30 723 1 Alveolar/Bronchiolar Adenoma Moribund
Respiratory System Lung Untreated Control 50 1 1 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 11 55 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 9 41 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 9 42 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 9 43 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 17 82 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 19 91 735 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 19 94 734 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 21 102 735 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 21 105 735 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 26 127 736 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 27 132 736 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 28 140 736 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1. % 50 29 143 730 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1. % 50 31 151 730 Multiple Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1. % 50 32 159 730 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1. % 50 34 169 730 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1. % 50 40 200 731 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 1. % 50 42 208 731 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 9 43 734 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 9 44 734 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 27 133 687 1 Alveolar/Bronchiolar Carcinoma Moribund
Respiratory System Lung 1. % 50 35 171 730 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 0.5 % 29 23 113 567 1 Hepatocellular Carcinoma Metastatic Moribund
Respiratory System Lung 1. % 50 29 144 730 1 Hepatocellular Carcinoma Metastatic Terminal Sacrifice
Respiratory System Lung 1. % 50 31 152 730 1 Hepatocellular Carcinoma Metastatic Terminal Sacrifice
Respiratory System Lung Untreated Control 50 6 28 734 1 Lymphoma Malignant Mixed Terminal Sacrifice
Respiratory System Lung Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Respiratory System Lung 0.5 % 29 16 76 626 1 Sarcoma Metastatic Moribund
Special Senses System Harderian Gland Untreated Control 2 10 49 734 1 Adenoma Terminal Sacrifice
Special Senses System Harderian Gland 1. % 3 31 152 730 1 Adenoma Terminal Sacrifice
Special Senses System Harderian Gland 1. % 3 34 169 730 1 Adenoma Terminal Sacrifice
Special Senses System Harderian Gland 1. % 3 41 201 731 1 Adenoma Terminal Sacrifice
Urinary System Kidney 1. % 50 30 147 308 1 Adenocarcinoma Dead
Urinary System Kidney Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund
Urinary System Kidney 0.5 % 23 16 76 626 1 Sarcoma Metastatic Moribund
Urinary System Urinary Bladder Untreated Control 50 6 27 449 1 Lymphoma Malignant Undifferentiated Cell Type Moribund