If this is the first time you are viewing this file, please choose 'Save As' from the 'File' menu and resave this file as an Excel file type. This will greatly speed up future viewings of this file.

Short-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Isoprene
CASRN: ="78-79-5"
Study Number: C61825C
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0513505
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Pharynx Palate 7000 PPM 40 43 1022 366 1 Papilloma Terminal Sacrifice
Endocrine System Adrenal Medulla 220 PPM 12 17 413 367 1 Ganglioneuroma Terminal Sacrifice
Endocrine System Pituitary Gland Vehicle Control 40 3 21 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Vehicle Control 40 3 24 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Vehicle Control 40 5 33 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Vehicle Control 40 7 42 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Vehicle Control 40 8 46 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Vehicle Control 40 8 48 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 10 220 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 11 222 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 13 231 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 13 234 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 13 235 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 14 237 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 70 PPM 18 16 246 368 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 220 PPM 14 19 424 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 220 PPM 14 20 426 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 220 PPM 14 24 450 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 700 PPM 14 28 627 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 700 PPM 14 28 629 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 700 PPM 14 31 645 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 700 PPM 14 32 647 367 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 2200 PPM 14 34 816 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 2200 PPM 14 35 825 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 2200 PPM 14 39 842 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 41 1015 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 42 1016 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 43 1023 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 43 1025 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 44 1029 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 45 1035 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 46 1038 366 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland 7000 PPM 40 47 1043 366 1 Adenoma Terminal Sacrifice
Genital System Epididymis 220 PPM 12 24 449 367 1 Mesothelioma Benign Terminal Sacrifice
Genital System Epididymis 7000 PPM 40 48 1048 366 1 Mesothelioma Benign Terminal Sacrifice
Genital System Epididymis 2200 PPM 11 37 833 366 1 Mesothelioma Nos Terminal Sacrifice
Genital System Testes Interstit Cell Vehicle Control 40 1 11 368 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell Vehicle Control 40 3 22 368 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell Vehicle Control 40 8 50 368 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 70 PPM 40 10 219 368 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 70 PPM 40 12 226 368 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 70 PPM 40 14 238 368 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 220 PPM 40 17 412 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 220 PPM 40 19 421 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 220 PPM 40 23 442 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 220 PPM 40 23 443 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 27 623 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 27 624 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 28 626 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 28 630 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 30 636 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 30 640 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 700 PPM 40 31 641 367 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 33 813 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 34 819 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 34 820 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 37 833 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 38 838 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 38 839 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 40 846 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 2200 PPM 39 40 848 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 41 1011 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 41 1014 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 43 1022 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 44 1029 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 45 1031 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 45 1032 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 47 1043 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 48 1046 366 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 7000 PPM 40 48 1048 366 Multiple Adenoma Terminal Sacrifice
Genital System Testes 70 PPM 40 11 221 368 1 Leukemia Mononuclear Terminal Sacrifice
Genital System Testes 70 PPM 40 12 227 368 1 Leukemia Mononuclear Terminal Sacrifice
Hematopoietic System Spleen 70 PPM 15 11 221 368 1 Leukemia Mononuclear Terminal Sacrifice
Hematopoietic System Spleen 70 PPM 15 12 227 368 1 Leukemia Mononuclear Terminal Sacrifice
Integumentary System Mammary Gland 700 PPM 11 27 623 367 1 Fibroadenoma Terminal Sacrifice
Integumentary System Skin 220 PPM 12 21 435 367 1 Sarcoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 40 3 24 368 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 70 PPM 40 15 244 368 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 7000 PPM 40 42 1016 366 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice