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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Methyl carbamate
CASRN: ="598-55-0"
Study Number: C55594
Exposure Route: Gavage
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Jejunum 001.0 G/KG 34 NA 1_C01 112.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
Alimentary System Intestine Small Jejunum 500.0 MG/KG 6 NA 2_C50 112.00 1 Adenomatous Polyp, Nos Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C26 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 3_C30 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 3_C38 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Vehicle Control 50 NA 3_C03 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C06 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C21 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C33 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C34 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C39 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C40 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C41 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C43 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C45 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Vehicle Control 50 NA 3_C48 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 001.0 G/KG 49 NA 1_C02 112.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C05 112.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C05 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C06 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C19 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C20 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C24 112.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C28 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C31 112.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C35 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C44 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 001.0 G/KG 49 NA 1_C01 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 001.0 G/KG 49 NA 1_C38 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 001.0 G/KG 49 NA 1_C40 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 001.0 G/KG 49 NA 1_C42 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 001.0 G/KG 49 NA 1_C49 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 001.0 G/KG 49 NA 1_C50 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C13 112.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C25 112.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 500.0 MG/KG 50 NA 2_C02 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C04 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C05 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C10 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C14 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C18 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C21 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C21 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C28 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C34 112.00 1 Hemangiosarcoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C35 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C36 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C37 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C42 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C43 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C44 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C44 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C49 112.00 1 Lymphoma, Undifferentiated-Malignant Type Terminal Sacrifice
Alimentary System Liver 500.0 MG/KG 50 NA 2_C50 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 50 NA 3_C34 112.00 1 Hemangioma Terminal Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 NA 3_C34 112.00 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 NA 3_C35 112.00 1 Mast-Cell Sarcoma Terminal Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 50 NA 3_C48 112.00 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach 001.0 G/KG 45 NA 1_C08 112.00 1 Squamous Cell Papilloma Terminal Sacrifice
Alimentary System Stomach Forestomach 001.0 G/KG 45 NA 1_C36 112.00 1 Squamous Cell Papilloma Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_C08 112.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_C02 112.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_C25 112.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Vehicle Control NA NA 3_C12 112.00 1 Hemangiosarcoma Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 001.0 G/KG NA NA 1_C44 112.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 001.0 G/KG NA NA 1_C18 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 001.0 G/KG NA NA 1_C23 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 001.0 G/KG NA NA 1_C34 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 001.0 G/KG NA NA 1_C40 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 001.0 G/KG NA NA 1_C42 112.00 1 Lymphoma, Histiocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C03 112.00 1 Lymphoma, Undifferentiated-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C15 112.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C38 112.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C41 112.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C47 112.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C48 112.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C02 112.00 1 Lymphoma, Histiocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C14 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C17 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C40 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 500.0 MG/KG NA NA 2_C43 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Vehicle Control NA NA 3_C03 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Vehicle Control NA NA 3_C09 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified Vehicle Control NA NA 3_C12 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified 001.0 G/KG NA NA 1_C26 112.00 1 Fibrosarcoma Natural Death
All Others Unspecified 001.0 G/KG NA NA 1_C32 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified 001.0 G/KG NA NA 1_C42 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified 500.0 MG/KG NA NA 2_C45 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 500.0 MG/KG NA NA 2_C41 112.00 1 Fibrous Histiocytoma, Malignant Natural Death
All Others Unspecified 500.0 MG/KG NA NA 2_C08 112.00 1 Fibrosarcoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla Vehicle Control 49 NA 3_C10 112.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Vehicle Control 49 NA 3_C05 112.00 1 Cortical Adenoma Natural Death
Endocrine System Adrenal gland Vehicle Control 49 NA 3_C45 112.00 1 Cortical Adenoma Terminal Sacrifice
Endocrine System Adrenal gland 001.0 G/KG 47 NA 1_C48 112.00 1 Cortical Adenoma Terminal Sacrifice
Endocrine System Thyroid Vehicle Control 50 NA 3_C15 112.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Endocrine System Thyroid Vehicle Control 50 NA 3_C21 112.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Genital System Penis Prepuce Nos 001.0 G/KG NA NA 1_C49 112.00 1 Mast-Cell Tumor Terminal Sacrifice
Genital System Testis Vehicle Control 49 NA 3_C03 112.00 1 Interstitial-Cell Tumor Terminal Sacrifice
Genital System Testis Vehicle Control 49 NA 3_C40 112.00 1 Interstitial-Cell Tumor Terminal Sacrifice
Hematopoietic System Bone marrow Vehicle Control 50 NA 3_C35 112.00 1 Mast-Cell Sarcoma Terminal Sacrifice
Hematopoietic System Lymph node Mandibular Lymph Node Vehicle Control 31 NA 3_C35 112.00 1 Mast-Cell Sarcoma, Metastatic Terminal Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node Vehicle Control 49 NA 3_C33 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 001.0 G/KG 49 NA 1_C08 112.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
Hematopoietic System Spleen 500.0 MG/KG 18 NA 2_C42 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C05 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_C25 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_C26 112.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_C38 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_C49 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Vehicle Control 50 NA 3_C06 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C09 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C33 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C35 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C41 112.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C42 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C43 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Vehicle Control 50 NA 3_C45 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C02 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 001.0 G/KG 49 NA 1_C19 112.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 001.0 G/KG 49 NA 1_C19 112.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung 001.0 G/KG 49 NA 1_C28 112.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung 001.0 G/KG 49 NA 1_C01 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C01 112.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C12 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C13 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C15 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C32 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C32 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C33 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C33 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 001.0 G/KG 49 NA 1_C42 112.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C11 112.00 1 Alveolar/Bronchiolar Adenoma Dosing Accident
Respiratory System Lung 500.0 MG/KG 50 NA 2_C05 112.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C09 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C14 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C16 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C18 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C23 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C40 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C46 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 500.0 MG/KG 50 NA 2_C50 112.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_C01 112.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Vehicle Control NA NA 3_C24 112.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 500.0 MG/KG NA NA 2_C24 112.00 1 Adenoma, Nos Terminal Sacrifice
Urinary System Kidney 500.0 MG/KG 50 NA 2_C15 112.00 1 Tubular-Cell Adenoma Natural Death