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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Methyl methacrylate
CASRN: ="80-62-6"
Study Number: C50680
Exposure Route: Inhalation
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 50 NA 3_022 115.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver Untreated Control 50 NA 3_023 115.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver Untreated Control 50 NA 3_035 115.00 1 Lymphoma, Nos-Malignant Natural Death
Alimentary System Liver Untreated Control 50 NA 3_010 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_016 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_024 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_046 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_048 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_039 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_045 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_045 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_012 115.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 500 PPM 48 NA 2_041 115.00 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver 500 PPM 48 NA 2_018 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_032 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_003 115.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_020 115.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_042 115.00 1 Osteosarcoma, Metastatic Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_049 115.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_011 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_034 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_036 115.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 10 PPM NA NA 1_031 115.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 10 PPM NA NA 1_043 115.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 10 PPM NA NA 1_033 115.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 10 PPM NA NA 1_046 115.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos 10 PPM NA NA 1_017 115.00 1 Lymphoma, Lymphocytic-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 500 PPM NA NA 2_035 115.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 500 PPM NA NA 2_021 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 500 PPM NA NA 2_036 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Shoulder Nos Untreated Control NA NA 3_042 115.00 1 Osteosarcoma Natural Death
All Others Unspecified Thoracic Cavity Nos 10 PPM NA NA 1_032 115.00 1 Adenocarcinoma, Nos Natural Death
All Others Unspecified Untreated Control NA NA 3_042 115.00 1 Osteosarcoma, Invasive Natural Death
All Others Unspecified Untreated Control NA NA 3_004 115.00 1 Hibernoma Scheduled Sacrifice
Endocrine System Adrenal gland Capsule Untreated Control 50 NA 3_011 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Adrenal gland Capsule Untreated Control 50 NA 3_048 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Adrenal gland Untreated Control 50 NA 3_031 115.00 1 Adenoma, Nos Natural Death
Endocrine System Adrenal gland 500 PPM 46 NA 2_036 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Intermedia Untreated Control 49 NA 3_048 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Intermedia 10 PPM 39 NA 1_038 115.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_039 115.00 1 Adenoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_012 115.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland Untreated Control 49 NA 3_014 115.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland Untreated Control 49 NA 3_020 115.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland Untreated Control 49 NA 3_035 115.00 1 Adenoma, Nos Natural Death
Endocrine System Pituitary gland Untreated Control 49 NA 3_002 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_017 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_024 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_025 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_026 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_043 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland Untreated Control 49 NA 3_050 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 10 PPM 39 NA 1_028 115.00 1 Adenocarcinoma, Nos Moribund Sacrifice
Endocrine System Pituitary gland 10 PPM 39 NA 1_040 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 500 PPM 44 NA 2_007 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 500 PPM 44 NA 2_021 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Pituitary gland 500 PPM 44 NA 2_042 115.00 1 Adenoma, Nos Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 49 NA 3_014 115.00 1 Follicular-Cell Adenoma Natural Death
Endocrine System Thyroid Untreated Control 49 NA 3_028 115.00 1 Follicular-Cell Adenoma Natural Death
Endocrine System Thyroid Untreated Control 49 NA 3_002 115.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 49 NA 3_010 115.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Endocrine System Thyroid 10 PPM 48 NA 1_043 115.00 1 Follicular-Cell Adenoma Moribund Sacrifice
Endocrine System Thyroid 500 PPM 44 NA 2_038 115.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Genital System Ovary Untreated Control 50 NA 3_037 115.00 1 Sertoli-Cell Tumor Scheduled Sacrifice
Genital System Ovary Untreated Control 50 NA 3_045 115.00 1 Luteoma Scheduled Sacrifice
Genital System Ovary 10 PPM 47 NA 1_010 115.00 1 Teratoma, Nos Natural Death
Genital System Ovary 10 PPM 47 NA 1_036 115.00 1 Cystadenoma, Nos Natural Death
Genital System Ovary 10 PPM 47 NA 1_020 115.00 1 Papillary Cystadenoma, Nos Scheduled Sacrifice
Genital System Ovary 500 PPM 47 NA 2_013 115.00 1 Papillary Cystadenoma, Nos Scheduled Sacrifice
Genital System Uterus Untreated Control 48 NA 3_013 115.00 1 Hemangioma Moribund Sacrifice
Genital System Uterus Untreated Control 48 NA 3_006 115.00 1 Adenocarcinoma, Nos Natural Death
Genital System Uterus Untreated Control 48 NA 3_005 115.00 1 Endometrial Stromal Polyp Scheduled Sacrifice
Genital System Uterus Untreated Control 48 NA 3_018 115.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Genital System Uterus Untreated Control 48 NA 3_034 115.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Genital System Uterus 500 PPM 47 NA 2_001 115.00 1 Hemangiosarcoma Scheduled Sacrifice
Hematopoietic System Lymph node Mandibular Lymph Node Untreated Control 36 NA 3_015 115.00 1 Squamous Cell Carcinoma, Metastatic Moribund Sacrifice
Hematopoietic System Lymph node Untreated Control 46 NA 3_015 115.00 1 Squamous Cell Carcinoma, Metastatic Moribund Sacrifice
Hematopoietic System Spleen Untreated Control 50 NA 3_024 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen 10 PPM 50 NA 1_049 115.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 10 PPM 50 NA 1_014 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen 500 PPM 47 NA 2_025 115.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
Hematopoietic System Spleen 500 PPM 47 NA 2_001 115.00 1 Hemangiosarcoma, Metastatic Scheduled Sacrifice
Hematopoietic System Spleen 500 PPM 47 NA 2_006 115.00 1 Hemangiosarcoma Scheduled Sacrifice
Integumentary System Mammary gland Untreated Control 34 NA 3_013 115.00 1 Adenosquamous Carcinoma Moribund Sacrifice
Integumentary System Mammary gland Untreated Control 34 NA 3_035 115.00 1 Acinar-Cell Carcinoma Natural Death
Integumentary System Mammary gland 10 PPM 31 NA 1_001 115.00 1 Mixed Tumor, Malignant Scheduled Sacrifice
Integumentary System Mammary gland 10 PPM 31 NA 1_008 115.00 1 Mixed Tumor, Malignant Scheduled Sacrifice
Integumentary System Skin Untreated Control 46 NA 3_015 115.00 1 Squamous Cell Carcinoma Moribund Sacrifice
Integumentary System Skin 10 PPM 48 NA 1_015 115.00 1 Squamous Cell Carcinoma Moribund Sacrifice
Nervous System Brain 10 PPM 50 NA 1_008 115.00 1 Neurofibrosarcoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_006 115.00 1 Adenocarcinoma, Nos, Metastatic Natural Death
Respiratory System Lung Untreated Control 49 NA 3_028 115.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Untreated Control 49 NA 3_043 115.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 500 PPM 49 NA 2_009 115.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 500 PPM 49 NA 2_015 115.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung 500 PPM 49 NA 2_041 115.00 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung 500 PPM 49 NA 2_013 115.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 500 PPM 49 NA 2_022 115.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 500 PPM 49 NA 2_045 115.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 500 PPM NA NA 2_010 115.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 500 PPM NA NA 2_042 115.00 1 Adenoma, Nos Scheduled Sacrifice
Urinary System Kidney 500 PPM 47 NA 2_045 115.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice