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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Methyl methacrylate
CASRN: ="80-62-6"
Study Number: C50680
Exposure Route: Inhalation
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Untreated Control 50 NA 3_008 116.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_023 116.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_006 116.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 50 NA 3_021 116.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 50 NA 3_001 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_001 116.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_009 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_015 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_024 116.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_025 116.00 1 Hemangiosarcoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_025 116.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_029 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_033 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_034 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_037 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_045 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_046 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_049 116.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_010 115.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver 10 PPM 49 NA 1_009 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_021 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_027 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_028 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_033 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_043 115.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 10 PPM 49 NA 1_050 115.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_016 116.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_050 116.00 1 Hemangiosarcoma Moribund Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_005 116.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 500 PPM 48 NA 2_009 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_013 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_019 116.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_030 116.00 1 Hepatocellular Adenoma Scheduled Sacrifice
Alimentary System Liver 500 PPM 48 NA 2_046 116.00 1 Hepatocellular Carcinoma Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_039 116.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_011 116.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 500 PPM NA NA 2_032 116.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 500 PPM NA NA 2_035 116.00 1 Lymphoma, Mixed-Malignant Type Scheduled Sacrifice
All Others Unspecified 10 PPM NA NA 1_045 115.00 1 Neurofibroma Scheduled Sacrifice
All Others Unspecified 500 PPM NA NA 2_016 116.00 1 Hemangiosarcoma Moribund Sacrifice
Endocrine System Adrenal gland Medulla 500 PPM 48 NA 2_027 116.00 1 Pheochromocytoma Scheduled Sacrifice
Endocrine System Adrenal gland Untreated Control 50 NA 3_006 116.00 1 Cortical Carcinoma Natural Death
Endocrine System Adrenal gland 10 PPM 50 NA 1_008 115.00 1 Cortical Adenoma Scheduled Sacrifice
Endocrine System Pituitary gland 500 PPM 43 NA 2_036 116.00 1 Acidophil Carcinoma Moribund Sacrifice
Endocrine System Thyroid 500 PPM 50 NA 2_034 116.00 1 Follicular-Cell Adenoma Scheduled Sacrifice
Genital System Testis Untreated Control 49 NA 3_043 116.00 1 Interstitial-Cell Tumor Scheduled Sacrifice
Genital System Testis 500 PPM 50 NA 2_043 116.00 1 Interstitial-Cell Tumor Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 50 NA 3_031 116.00 1 Lymphoma, Histiocytic-Malignant Type Scheduled Sacrifice
Hematopoietic System Spleen 500 PPM 48 NA 2_044 116.00 1 Hemangiosarcoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_008 116.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_008 116.00 1 Hepatocellular Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_005 116.00 1 Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung Untreated Control 50 NA 3_003 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_007 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_007 116.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_015 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_019 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_019 116.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_022 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_027 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_041 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_045 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_048 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10 PPM 50 NA 1_010 115.00 1 Hemangiosarcoma, Metastatic Natural Death
Respiratory System Lung 10 PPM 50 NA 1_003 115.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10 PPM 50 NA 1_017 115.00 1 Alveolar/Bronchiolar Carcinoma Scheduled Sacrifice
Respiratory System Lung 10 PPM 50 NA 1_043 115.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10 PPM 50 NA 1_047 115.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Respiratory System Lung 10 PPM 50 NA 1_049 115.00 1 Adenocarcinoma, Nos, Metastatic Scheduled Sacrifice
Respiratory System Lung 500 PPM 50 NA 2_043 116.00 1 Alveolar/Bronchiolar Adenoma Scheduled Sacrifice
Special Senses System Ear 500 PPM 1 NA 2_045 116.00 1 Fibrosarcoma Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_023 116.00 1 Adenoma, Nos Moribund Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_022 116.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_024 116.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_035 116.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_040 116.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_049 116.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10 PPM NA NA 1_005 115.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10 PPM NA NA 1_018 115.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10 PPM NA NA 1_023 115.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10 PPM NA NA 1_028 115.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 10 PPM NA NA 1_049 115.00 1 Adenocarcinoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 500 PPM NA NA 2_013 116.00 1 Adenoma, Nos Scheduled Sacrifice
Special Senses System Harderian gland Hardarian Gland 500 PPM NA NA 2_048 116.00 1 Adenoma, Nos Scheduled Sacrifice
Urinary System Kidney Untreated Control 50 NA 3_041 116.00 1 Tubular-Cell Adenoma Scheduled Sacrifice