If this is the first time you are viewing this file, please choose 'Save As' from the 'File' menu and resave this file as an Excel file type. This will greatly speed up future viewings of this file.

Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Oxytetracycline hydrochloride
CASRN: ="2058-46-0"
Study Number: C56473
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Duodenum 6300 PPM 47 NA 2_026 112.00 1 Adenocarcinoma, Nos Terminal Sacrifice
Alimentary System Intestine Small Ileum Untreated Control 50 NA 3_150 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_109 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_110 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_120 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_128 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_130 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_135 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_143 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_148 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_111 113.00 1 Hemangioma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_115 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_121 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_136 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_138 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_140 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_142 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_144 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_145 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_146 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 NA 3_149 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_002 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_020 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_030 112.00 1 Hemangiosarcoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_031 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_035 112.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_035 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_038 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_015 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 6300 PPM 50 NA 2_003 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_010 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_022 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_024 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_026 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_027 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_029 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_029 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_032 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 6300 PPM 50 NA 2_037 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_069 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_073 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_082 113.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_088 113.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_054 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_056 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_059 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_061 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_063 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_064 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_078 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_084 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_085 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_093 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_095 113.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_096 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 50 NA 1_100 113.00 1 Hepatocellular Carcinoma Terminal Sacrifice
All Others Unspecified Abdominal Cavity Untreated Control NA NA 3_104 113.00 1 Hemangiosarcoma, Metastatic Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_110 113.00 1 Lymphoma, Histiocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_119 113.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_148 113.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_116 113.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_121 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_137 113.00 1 Lymphoma, Histiocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_146 113.00 1 Lymphoma, Lymphocytic-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 6300 PPM NA NA 2_002 112.00 1 Sarcoma, Nos Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 6300 PPM NA NA 2_035 112.00 1 Lymphoma, Mixed-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_055 113.00 1 Lymphoma, Histiocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_071 113.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_052 113.00 1 Lymphoma, Mixed-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_066 113.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_051 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_065 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 1_084 113.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Pelvis 12500 PPM NA NA 1_077 113.00 1 Sarcoma, Nos Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_107 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_110 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_120 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_123 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_130 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_133 113.00 1 Sarcoma, Nos Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_135 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_135 113.00 1 Sarcoma, Nos Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_139 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Untreated Control NA NA 3_126 113.00 1 Sarcoma, Nos Natural Death
All Others Unspecified Untreated Control NA NA 3_106 113.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Untreated Control NA NA 3_108 113.00 1 Osteosarcoma Terminal Sacrifice
All Others Unspecified Untreated Control NA NA 3_124 113.00 1 Fibroma Terminal Sacrifice
All Others Unspecified Untreated Control NA NA 3_136 113.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 6300 PPM NA NA 2_004 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 6300 PPM NA NA 2_008 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 6300 PPM NA NA 2_038 112.00 1 Sarcoma, Nos Moribund Sacrifice
All Others Unspecified 6300 PPM NA NA 2_049 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 6300 PPM NA NA 2_010 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified 6300 PPM NA NA 2_018 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 6300 PPM NA NA 2_025 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 6300 PPM NA NA 2_034 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 6300 PPM NA NA 2_044 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified 6300 PPM NA NA 2_046 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 12500 PPM NA NA 1_068 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 12500 PPM NA NA 1_073 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 12500 PPM NA NA 1_075 113.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified 12500 PPM NA NA 1_056 113.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 12500 PPM NA NA 1_070 113.00 1 Fibroma Terminal Sacrifice
Cardiovascular System Heart Atrium 12500 PPM 50 NA 1_074 113.00 1 Hemangioma Terminal Sacrifice
Endocrine System Adrenal gland Medulla Untreated Control 50 NA 3_128 113.00 1 Pheochromocytoma Moribund Sacrifice
Endocrine System Adrenal gland Medulla Untreated Control 50 NA 3_127 113.00 1 Pheochromocytoma, Malignant Natural Death
Endocrine System Adrenal gland Medulla Untreated Control 50 NA 3_145 113.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 6300 PPM 49 NA 2_006 112.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 6300 PPM 49 NA 2_023 112.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 6300 PPM 49 NA 2_025 112.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 6300 PPM 49 NA 2_027 112.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 6300 PPM 49 NA 2_032 112.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 12500 PPM 50 NA 1_085 113.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland Medulla 12500 PPM 50 NA 1_094 113.00 1 Pheochromocytoma Terminal Sacrifice
Endocrine System Adrenal gland 6300 PPM 49 NA 2_038 112.00 1 Cortical Adenoma Moribund Sacrifice
Endocrine System Adrenal gland 6300 PPM 49 NA 2_029 112.00 1 Cortical Adenoma Terminal Sacrifice
Endocrine System Thyroid 12500 PPM 50 NA 1_090 113.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Endocrine System Thyroid 12500 PPM 50 NA 1_096 113.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Genital System Testis 12500 PPM 50 NA 1_067 113.00 1 Hemangioma Terminal Sacrifice
Hematopoietic System Spleen Untreated Control 50 NA 3_104 113.00 1 Hemangiosarcoma Moribund Sacrifice
Hematopoietic System Spleen Untreated Control 50 NA 3_126 113.00 1 Hemangiosarcoma Natural Death
Hematopoietic System Spleen 6300 PPM 50 NA 2_030 112.00 1 Sarcoma, Nos Moribund Sacrifice
Integumentary System Skin Untreated Control 49 NA 3_149 113.00 1 Squamous Cell Papilloma Terminal Sacrifice
Integumentary System Skin 6300 PPM 50 NA 2_033 112.00 1 Squamous Cell Papilloma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_107 113.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_130 113.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_127 113.00 1 Pheochromocytoma, Metastatic Natural Death
Respiratory System Lung Untreated Control 50 NA 3_101 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_103 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_113 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_115 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_136 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_138 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_149 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 NA 3_150 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_008 112.00 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_050 112.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_003 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_007 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_009 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_009 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_011 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_018 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_021 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 6300 PPM 50 NA 2_029 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_069 113.00 1 Hepatocellular Carcinoma, Metastatic Moribund Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_082 113.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_058 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_059 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_059 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_067 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_072 113.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 50 NA 1_094 113.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_137 113.00 1 Adenoma, Nos Terminal Sacrifice
Urinary System Kidney 12500 PPM 50 NA 1_069 113.00 1 Lymphoma, Lymphocytic-Malignant Type Moribund Sacrifice