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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Tetracycline hydrochloride
CASRN: ="64-75-5"
Study Number: C55561
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Large Intestinal Tract Untreated Control 37 NA 3_137 112.00 1 Lymphoma, Undifferentiated-Malignant Type Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_110 112.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_116 112.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_132 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_147 112.00 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_115 112.00 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 49 NA 3_140 112.00 1 Hemangiosarcoma Natural Death
Alimentary System Liver Untreated Control 49 NA 3_104 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_128 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_137 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_138 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_142 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_146 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 49 NA 3_148 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_022 112.00 1 Hepatocellular Adenoma Moribund Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_001 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_013 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_016 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_018 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_021 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_023 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_024 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_025 112.00 1 Hemangiosarcoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_025 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_032 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_035 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 12500 PPM 16 NA 2_044 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_052 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_053 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_058 112.00 1 Hemangiosarcoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_062 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_070 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_074 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_076 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_078 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_085 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_091 112.00 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25000 PPM 48 NA 1_100 112.00 1 Hepatocellular Carcinoma Terminal Sacrifice
All Others Unspecified Back Untreated Control NA NA 3_118 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Back Untreated Control NA NA 3_131 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified Back 12500 PPM NA NA 2_005 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Back 12500 PPM NA NA 2_041 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified Back 25000 PPM NA NA 1_092 112.00 1 Sarcoma, Nos Terminal Sacrifice
All Others Unspecified Groin 12500 PPM NA NA 2_045 112.00 1 Fibrosarcoma Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_102 112.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_117 112.00 1 Lymphoma, Lymphocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_123 112.00 1 Lymphoma, Histiocytic-Malignant Type Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_127 112.00 1 Lymphoma, Nos-Malignant Natural Death
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_122 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_137 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_141 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_144 112.00 1 Lymphoma, Undifferentiated-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 2_001 112.00 1 Lymphoma, Undifferentiated-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 2_036 112.00 1 Lymphoma, Undifferentiated-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 12500 PPM NA NA 2_049 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Multiple Organs Nos 25000 PPM NA NA 1_051 112.00 1 Fibrosarcoma Moribund Sacrifice
All Others Unspecified Multiple Organs Nos 25000 PPM NA NA 1_063 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
All Others Unspecified Shoulder 12500 PPM NA NA 2_038 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Trunk 25000 PPM NA NA 1_091 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified Untreated Control NA NA 3_136 112.00 1 Fibrosarcoma Natural Death
All Others Unspecified 25000 PPM NA NA 1_094 112.00 1 Sarcoma, Nos Natural Death
All Others Unspecified 25000 PPM NA NA 1_064 112.00 1 Fibrosarcoma Terminal Sacrifice
All Others Unspecified 25000 PPM NA NA 1_074 112.00 1 Fibroma Terminal Sacrifice
All Others Unspecified 25000 PPM NA NA 1_093 112.00 1 Fibrosarcoma Terminal Sacrifice
Endocrine System Thyroid Untreated Control 49 NA 3_131 112.00 1 Follicular-Cell Adenoma Terminal Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node Untreated Control 48 NA 3_126 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
Hematopoietic System Spleen 12500 PPM 49 NA 2_017 112.00 1 Hemangiosarcoma Terminal Sacrifice
Hematopoietic System Spleen 25000 PPM 47 NA 1_064 112.00 1 Lymphoma, Mixed-Malignant Type Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_115 112.00 1 Hepatocellular Carcinoma, Metastatic Natural Death
Respiratory System Lung Untreated Control 49 NA 3_104 112.00 1 Hepatocellular Carcinoma, Metastatic Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_120 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_125 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_133 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_139 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_146 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 49 NA 3_149 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 15 NA 2_008 112.00 1 Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung 12500 PPM 15 NA 2_001 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 15 NA 2_007 112.00 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 15 NA 2_015 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 15 NA 2_016 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 12500 PPM 15 NA 2_030 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 25000 PPM 48 NA 1_052 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 25000 PPM 48 NA 1_056 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 25000 PPM 48 NA 1_059 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 25000 PPM 48 NA 1_086 112.00 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_113 112.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_141 112.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_148 112.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland Untreated Control NA NA 3_150 112.00 1 Adenoma, Nos Terminal Sacrifice
Special Senses System Harderian gland Hardarian Gland 25000 PPM NA NA 1_057 112.00 1 Adenoma, Nos Terminal Sacrifice
Urinary System Kidney Untreated Control 49 NA 3_126 112.00 1 Tubular-Cell Adenocarcinoma Terminal Sacrifice