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Long-Term Individual Animal Neoplastic Diagnosis

Study Information:

Chemical Name: Vinyl toluene
CASRN: ="25013-15-4"
Study Number: C56406
Exposure Route: RESPIRATORY EXPOSURE WHOLE BODY
TDMS Number: 0507002
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Alimentary System Intestine Large Cecum 10 PPM 11 258 8 632 1 Lymphoma Malignant Histiocytic Natural Death
Alimentary System Intestine Large Cecum Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Alimentary System Intestine Large Colon, Serosa 25 PPM 50 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Alimentary System Intestine Small Duodenum 10 PPM 15 291 41 695 1 Polyp Adenomatous Moribund Sacrifice
Alimentary System Intestine Small Duodenum 25 PPM 50 197 47 735 1 Polyp Adenomatous Terminal Sacrifice
Alimentary System Intestine Small Jejunum 10 PPM 15 286 36 733 1 Adenocarcinoma Terminal Sacrifice
Alimentary System Intestine Small Jejunum Untreated Control 50 82 32 733 1 Lymphoma Malignant Histiocytic Terminal Sacrifice
Alimentary System Intestine Small Jejunum 10 PPM 15 261 11 735 1 Lymphoma Malignant Mixed Terminal Sacrifice
Alimentary System Liver Untreated Control 50 63 13 529 Multiple Hemangiosarcoma Natural Death
Alimentary System Liver Untreated Control 50 97 47 588 1 Hepatocellular Adenoma Natural Death
Alimentary System Liver Untreated Control 50 64 14 733 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 65 15 733 Multiple Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 67 17 733 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 68 18 733 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 77 27 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 84 34 732 Multiple Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 93 43 734 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 269 19 733 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 290 40 732 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 188 38 733 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 193 43 735 1 Hepatocellular Adenoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 51 1 673 Multiple Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 55 5 567 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 57 7 670 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 74 24 658 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver Untreated Control 50 97 47 588 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 50 98 48 514 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver Untreated Control 50 59 9 732 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 82 32 733 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 86 36 732 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver Untreated Control 50 89 39 731 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 253 3 567 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 10 PPM 24 255 5 553 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 10 PPM 24 257 7 724 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 10 PPM 24 259 9 574 Multiple Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 10 PPM 24 277 27 623 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 10 PPM 24 258 8 632 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 10 PPM 24 268 18 434 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 10 PPM 24 288 38 682 1 Hepatocellular Carcinoma Natural Death
Alimentary System Liver 10 PPM 24 252 2 732 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 266 16 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 282 32 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 284 34 733 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 194 44 703 1 Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 25 PPM 50 195 45 702 Multiple Hepatocellular Carcinoma Moribund Sacrifice
Alimentary System Liver 25 PPM 50 157 7 732 Multiple Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 159 9 731 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 165 15 735 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 168 18 735 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 178 28 735 Multiple Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 184 34 734 Multiple Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 185 35 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 187 37 733 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 198 48 734 Multiple Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 25 PPM 50 200 50 734 1 Hepatocellular Carcinoma Terminal Sacrifice
Alimentary System Liver 10 PPM 24 258 8 632 1 Lymphoma Malignant Histiocytic Natural Death
Alimentary System Liver 25 PPM 50 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Alimentary System Mesentery Fat 25 PPM 3 167 17 735 1 Hemangiosarcoma Terminal Sacrifice
Alimentary System Mesentery Untreated Control 6 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Alimentary System Mesentery Untreated Control 6 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Alimentary System Pancreas Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Alimentary System Pancreas 25 PPM 50 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Alimentary System Salivary Glands Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Alimentary System Salivary Glands Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Alimentary System Stomach Forestomach Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Endocrine System Adrenal Gland Capsule Untreated Control 50 65 15 733 Multiple Adenoma Terminal Sacrifice
Endocrine System Adrenal Gland Capsule Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Endocrine System Adrenal Gland Capsule 25 PPM 50 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Endocrine System Adrenal Gland Cortex Untreated Control 50 87 37 732 1 Adenoma Terminal Sacrifice
Endocrine System Adrenal Gland Medulla Untreated Control 50 58 8 732 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Adrenal Gland Medulla 25 PPM 50 196 46 735 1 Pheochromocytoma Benign Terminal Sacrifice
Endocrine System Islets Pancreatic 25 PPM 50 171 21 733 1 Adenoma Terminal Sacrifice
Endocrine System Islets Pancreatic 25 PPM 50 200 50 734 1 Adenoma Terminal Sacrifice
Endocrine System Parathyroid Gland Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Endocrine System Pituitary Gland Pars Distalis Untreated Control 50 58 8 732 1 Adenoma Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis 25 PPM 50 151 1 732 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel Untreated Control 50 97 47 588 1 Adenocarcinoma Natural Death
Endocrine System Thyroid Gland Follicular Cel Untreated Control 50 76 26 735 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel Untreated Control 50 83 33 733 1 Adenoma Terminal Sacrifice
Endocrine System Thyroid Gland Follicular Cel Untreated Control 50 94 44 734 1 Adenoma Terminal Sacrifice
Genital System Epididymis Untreated Control 50 82 32 733 1 Lymphoma Malignant Histiocytic Terminal Sacrifice
Genital System Epididymis Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Genital System Prostate Serosa 25 PPM 50 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Genital System Prostate Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Genital System Seminal Vesicle Serosa 25 PPM 49 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Genital System Seminal Vesicle Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Genital System Testes Interstit Cell 10 PPM 13 300 50 733 1 Adenoma Terminal Sacrifice
Genital System Testes Interstit Cell 25 PPM 50 164 14 735 1 Adenoma Terminal Sacrifice
Hematopoietic System Bone Marrow 10 PPM 11 258 8 632 1 Lymphoma Malignant Histiocytic Natural Death
Hematopoietic System Bone Marrow Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Hematopoietic System Lymph Node Mediastinal 10 PPM 26 252 2 732 1 Lymphoma Malignant Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mediastinal Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10 PPM 26 258 8 632 1 Lymphoma Malignant Histiocytic Natural Death
Hematopoietic System Lymph Node Mesenteric Untreated Control 50 68 18 733 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Untreated Control 50 60 10 732 1 Lymphoma Malignant Mixed Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10 PPM 26 261 11 735 1 Lymphoma Malignant Mixed Terminal Sacrifice
Hematopoietic System Lymph Node Pancreatic Untreated Control 50 83 33 733 1 Lymphoma Malignant Histiocytic Terminal Sacrifice
Hematopoietic System Spleen Capsule 25 PPM 50 198 48 734 1 Sarcoma Metastatic Terminal Sacrifice
Hematopoietic System Spleen 10 PPM 16 254 4 731 1 Hemangiosarcoma Terminal Sacrifice
Hematopoietic System Spleen 10 PPM 16 258 8 632 1 Lymphoma Malignant Histiocytic Natural Death
Hematopoietic System Spleen 10 PPM 16 252 2 732 1 Lymphoma Malignant Histiocytic Terminal Sacrifice
Hematopoietic System Spleen Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Hematopoietic System Spleen Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Hematopoietic System Thymus Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Integumentary System Skin Subcut Tiss 25 PPM 49 194 44 703 1 Fibrosarcoma Moribund Sacrifice
Integumentary System Skin Subcut Tiss 10 PPM 31 254 4 731 1 Fibrous Histiocytoma Terminal Sacrifice
Integumentary System Skin Subcut Tiss 25 PPM 49 187 37 733 1 Hemangioma Terminal Sacrifice
Integumentary System Skin Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Musculoskeletal System Bone Untreated Control 50 87 37 732 1 Osteoma Terminal Sacrifice
Nervous System Brain Meninges Untreated Control 50 66 16 673 1 Hamartoma Moribund Sacrifice
Respiratory System Larynx Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Respiratory System Lung Untreated Control 50 53 3 687 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Untreated Control 50 90 40 714 1 Alveolar/Bronchiolar Adenoma Moribund Sacrifice
Respiratory System Lung Untreated Control 50 88 38 707 1 Alveolar/Bronchiolar Adenoma Natural Death
Respiratory System Lung Untreated Control 50 54 4 732 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 67 17 733 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 73 23 731 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 75 25 732 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 87 37 732 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 89 39 731 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 10 PPM 50 262 12 735 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 10 PPM 50 272 22 732 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 25 PPM 50 165 15 735 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung 25 PPM 50 171 21 733 1 Alveolar/Bronchiolar Adenoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 56 6 696 Multiple Alveolar/Bronchiolar Carcinoma Moribund Sacrifice
Respiratory System Lung Untreated Control 50 61 11 735 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 76 26 735 Multiple Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 10 PPM 50 265 15 358 Multiple Alveolar/Bronchiolar Carcinoma Natural Death
Respiratory System Lung 10 PPM 50 266 16 734 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung 10 PPM 50 282 32 734 1 Alveolar/Bronchiolar Carcinoma Terminal Sacrifice
Respiratory System Lung Untreated Control 50 51 1 673 1 Hepatocellular Carcinoma Metastatic Moribund Sacrifice
Respiratory System Lung Untreated Control 50 55 5 567 1 Hepatocellular Carcinoma Metastatic Moribund Sacrifice
Respiratory System Lung Untreated Control 50 86 36 732 1 Hepatocellular Carcinoma Metastatic Terminal Sacrifice
Respiratory System Lung 10 PPM 50 259 9 574 1 Hepatocellular Carcinoma Metastatic Moribund Sacrifice
Respiratory System Lung 10 PPM 50 288 38 682 1 Hepatocellular Carcinoma Metastatic Natural Death
Respiratory System Lung 10 PPM 50 282 32 734 1 Hepatocellular Carcinoma Metastatic Terminal Sacrifice
Respiratory System Lung 10 PPM 50 284 34 733 1 Hepatocellular Carcinoma Metastatic Terminal Sacrifice
Respiratory System Lung 10 PPM 50 252 2 732 1 Lymphoma Malignant Histiocytic Terminal Sacrifice
Respiratory System Lung Untreated Control 50 54 4 732 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Respiratory System Lung Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Special Senses System Harderian Gland Bilateral 10 PPM 1 278 28 735 1 Adenoma Terminal Sacrifice
Urinary System Kidney 10 PPM 13 258 8 632 1 Lymphoma Malignant Histiocytic Natural Death
Urinary System Kidney Untreated Control 50 54 4 732 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Urinary System Kidney Untreated Control 50 76 26 735 1 Lymphoma Malignant Lymphocytic Terminal Sacrifice
Urinary System Kidney Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice
Urinary System Urinary Bladder Untreated Control 50 57 7 670 1 Lymphoma Malignant Mixed Moribund Sacrifice