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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 1,1,2,2-Tetrachloroethane
CASRN: ="79-34-5"
Study Number: C03554E
Exposure Route: DOSED FEED
TDMS Number: 0355412
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Bile Duct 350 MG/KG 10 79 111 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 79 113 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 79 114 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 79 115 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 80 116 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 80 117 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 80 119 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 350 MG/KG 10 80 120 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 81 121 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 81 122 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 81 123 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 81 124 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 81 125 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 82 126 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 82 127 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 82 128 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 82 129 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 700 MG/KG 10 82 130 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 83 131 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 83 132 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 83 133 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 83 134 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 83 135 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 84 136 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 84 137 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 84 138 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 84 139 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Bile Duct 1400 MG/KG 10 84 140 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 88 MG/KG 10 75 92 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 88 MG/KG 10 76 96 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 77 101 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 77 103 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 77 104 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 77 105 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 78 106 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 78 107 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 78 108 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 78 109 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 175 MG/KG 10 78 110 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 79 111 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 79 112 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 79 113 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 79 114 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 79 115 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 116 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 117 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 118 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 119 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 120 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 121 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 122 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 123 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 124 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 125 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 126 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 127 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 128 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 129 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 130 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 131 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 132 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 133 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 134 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 135 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 136 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 137 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 138 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 139 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 140 92 1 Hypertrophy Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 79 115 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 116 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 350 MG/KG 10 80 119 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 122 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 123 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 81 125 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 127 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 128 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 129 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 700 MG/KG 10 82 130 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 131 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 83 132 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 139 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1400 MG/KG 10 84 140 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 71 71 92 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 71 72 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 71 74 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 72 77 92 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 72 78 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Untreated Control 10 72 79 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 73 81 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 73 82 92 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 73 83 92 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 73 84 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 73 85 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 88 MG/KG 10 75 95 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 88 MG/KG 10 76 99 92 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver 175 MG/KG 10 77 102 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 175 MG/KG 10 78 109 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 79 112 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 81 124 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 81 125 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 83 132 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 84 136 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 83 133 92 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 83 134 92 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver 175 MG/KG 10 78 107 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 175 MG/KG 10 78 110 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 79 111 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 79 113 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 79 114 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 79 115 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 80 116 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 80 117 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 80 118 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 80 119 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 350 MG/KG 10 80 120 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 81 122 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 81 123 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 81 125 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 82 126 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 82 127 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 82 128 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 82 129 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 700 MG/KG 10 82 130 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 83 133 92 1 Pigmentation Mild, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 83 134 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 83 135 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 84 136 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 84 137 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 84 138 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1400 MG/KG 10 84 140 92 1 Pigmentation Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach Vehicle Control 10 74 89 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Glandular Untreated Control 10 71 74 92 1 Cyst Minimal Terminal Sacrifice
Alimentary System Stomach Glandular Untreated Control 10 72 80 92 1 Cyst Minimal Terminal Sacrifice
Alimentary System Stomach Glandular Vehicle Control 10 74 86 92 1 Cyst Minimal Terminal Sacrifice
Alimentary System Stomach Glandular Vehicle Control 10 74 90 92 1 Cyst Minimal Terminal Sacrifice
Alimentary System Stomach Glandular 1400 MG/KG 10 83 134 92 1 Cyst Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 71 72 92 1 Hyperplasia Mild Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 71 74 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 71 75 92 1 Hyperplasia Mild Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 72 76 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Untreated Control 10 72 77 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 10 73 81 92 1 Hyperplasia Mild Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 10 73 85 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 10 74 86 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 10 74 87 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 10 74 89 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 10 74 90 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1400 MG/KG 10 83 131 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1400 MG/KG 10 83 133 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1400 MG/KG 10 84 136 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1400 MG/KG 10 84 138 92 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1400 MG/KG 10 84 140 92 1 Hyperplasia Mild Terminal Sacrifice
Endocrine System Adrenal Medulla Untreated Control 10 72 78 92 1 Angiectasis Mild Terminal Sacrifice
Endocrine System Adrenal Medulla 1400 MG/KG 10 83 135 92 1 Angiectasis Minimal Terminal Sacrifice
Endocrine System Pituitary Gland 1400 MG/KG 10 83 135 92 1 Cyst Mild Terminal Sacrifice
Genital System Clitoral Gland Untreated Control 10 71 75 92 1 Atrophy Mild Terminal Sacrifice
Genital System Clitoral Gland Untreated Control 10 72 76 92 1 Atrophy Minimal Terminal Sacrifice
Genital System Clitoral Gland Untreated Control 10 72 78 92 1 Atrophy Mild Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 73 81 92 1 Atrophy Mild Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 74 88 92 1 Atrophy Minimal Terminal Sacrifice
Genital System Clitoral Gland 1400 MG/KG 10 83 133 92 1 Atrophy Mild Terminal Sacrifice
Genital System Clitoral Gland 1400 MG/KG 10 83 134 92 1 Atrophy Mild Terminal Sacrifice
Genital System Clitoral Gland 1400 MG/KG 10 83 135 92 1 Atrophy Moderate Terminal Sacrifice
Genital System Clitoral Gland 1400 MG/KG 10 84 138 92 1 Atrophy Moderate Terminal Sacrifice
Genital System Clitoral Gland 1400 MG/KG 10 84 139 92 1 Atrophy Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Untreated Control 10 72 78 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 74 87 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 10 73 83 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 10 74 86 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 1400 MG/KG 10 83 132 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Spleen 1400 MG/KG 10 83 135 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 350 MG/KG 10 80 120 92 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte Vehicle Control 10 73 82 92 1 Necrosis Minimal Terminal Sacrifice
Hematopoietic System Thymus Thymocyte Vehicle Control 10 74 86 92 1 Necrosis Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 1400 MG/KG 10 84 138 92 1 Necrosis Mild Terminal Sacrifice
Hematopoietic System Thymus 1400 MG/KG 10 83 134 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 1400 MG/KG 10 84 138 92 1 Atrophy Minimal Terminal Sacrifice
Respiratory System Lung 175 MG/KG 7 77 101 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 74 87 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice