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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Transgenic LECM (1-Chloro-2-propanol, technical)
CASRN: ="127-00-4"
Study Number: C61983D
Exposure Route: DOSED WATER
TDMS Number: 0516007
Sex: Female
Strain and Species: P53(C57BL/6) Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular Vehicle Control 8 47 654 183 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 8 49 657 183 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 71 590 183 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 72 596 183 1 Vacuolization Cytoplasmic Minimal, Focal Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 76 643 184 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 74 618 184 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 41 580 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 42 586 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 43 604 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 46 631 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 47 654 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 48 656 183 1 Infiltration Cellular Minimal, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 49 657 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 50 659 183 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 71 590 183 1 Infiltration Cellular Mild, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 75 637 184 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 77 650 184 1 Infiltration Cellular Minimal, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 78 651 184 1 Infiltration Cellular Mild, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 79 652 184 1 Infiltration Cellular Mild, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 80 660 184 1 Infiltration Cellular Minimal, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 8 43 604 183 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 71 590 183 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 41 580 183 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 42 586 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 43 604 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 46 631 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 48 656 183 1 Infiltration Cellular Moderate, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 49 657 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 8 50 659 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 71 590 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 76 643 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 80 660 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Stomach Forestomach 1000 PPM 10 80 660 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 8 42 586 183 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 8 46 631 183 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 8 47 654 183 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule Vehicle Control 8 48 656 183 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 71 590 183 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 72 596 183 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 74 618 184 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 75 637 184 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 78 651 184 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 80 660 184 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 8 41 580 183 1 Degeneration Minimal, Focal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 8 42 586 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 8 46 631 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 8 47 654 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 8 48 656 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 8 49 657 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 71 590 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 72 596 183 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 74 618 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 75 637 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 76 643 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 77 650 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 78 651 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 79 652 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 80 660 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Genital System Uterus Endometrium Vehicle Control 1 41 580 183 1 Hyperplasia Moderate, Diffuse, Cystic Terminal Sacrifice
Genital System Uterus Endometrium 1000 PPM 1 77 650 184 1 Hyperplasia Moderate, Diffuse, Cystic Terminal Sacrifice
Hematopoietic System Thymus 1000 PPM 10 74 618 184 1 Hyperplasia Moderate, Focal, Atypical Terminal Sacrifice
Integumentary System Mammary Gland Duct 1000 PPM 10 74 618 184 1 Dilatation Mild Terminal Sacrifice
Respiratory System Lung Alveolus Vehicle Control 8 46 631 183 1 Infiltration Cellular Mild, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus Vehicle Control 8 47 654 183 1 Infiltration Cellular Mild, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus Vehicle Control 8 49 657 183 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus 1000 PPM 10 71 590 183 1 Infiltration Cellular Mild, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus 1000 PPM 10 72 596 183 1 Infiltration Cellular Mild, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus 1000 PPM 10 73 613 184 1 Infiltration Cellular Minimal, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus 1000 PPM 10 75 637 184 1 Infiltration Cellular Minimal, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus 1000 PPM 10 76 643 184 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus 1000 PPM 10 80 660 184 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 41 580 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 42 586 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 43 604 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 46 631 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 47 654 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 48 656 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 49 657 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 50 659 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 71 590 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 72 596 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 73 613 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 74 618 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 75 637 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 76 643 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 77 650 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 78 651 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 79 652 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 80 660 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 41 580 183 1 Inflammation Minimal, Focal, Suppurative, Acute Terminal Sacrifice
Respiratory System Lung Vehicle Control 8 46 631 183 1 Inflammation Mild, Focal, Suppurative, Acute Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 72 596 183 1 Inflammation Minimal, Focal, Suppurative, Acute Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 PPM 10 72 596 183 1 Regeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 PPM 10 75 637 184 1 Regeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 71 590 183 1 Casts Protein Minimal, Focal Terminal Sacrifice
Urinary System Kidney Vehicle Control 8 41 580 183 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 8 43 604 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 8 46 631 183 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 8 47 654 183 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 8 48 656 183 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 8 50 659 183 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 74 618 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 75 637 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 76 643 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 78 651 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 79 652 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice