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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Transgenic LECM (1-Chloro-2-propanol, technical)
CASRN: ="127-00-4"
Study Number: C61983D
Exposure Route: DOSED WATER
TDMS Number: 0516007
Sex: Male
Strain and Species: P53(C57BL/6) Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular Vehicle Control 10 10 724 184 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 3 667 184 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 5 670 184 1 Hypertrophy Mild, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 6 676 184 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 31 671 185 1 Hypertrophy Mild, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 32 672 185 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 33 686 185 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 36 706 185 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 1 663 184 1 Vacuolization Cytoplasmic Moderate, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 7 679 184 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 8 689 184 1 Vacuolization Cytoplasmic Mild, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 9 722 184 1 Vacuolization Cytoplasmic Mild, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 34 687 185 1 Vacuolization Cytoplasmic Mild, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 38 710 185 1 Vacuolization Cytoplasmic Moderate, Diffuse Terminal Sacrifice
Alimentary System Liver Centrilobular 1000 PPM 10 40 732 185 1 Vacuolization Cytoplasmic Moderate, Diffuse Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 8 689 184 1 Hematopoietic Cell Proliferation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 2 664 184 1 Infiltration Cellular Mild, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 3 667 184 1 Infiltration Cellular Minimal, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 4 668 184 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 6 676 184 1 Infiltration Cellular Mild, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 8 689 184 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 9 722 184 1 Infiltration Cellular Minimal, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 33 686 185 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 36 706 185 1 Infiltration Cellular Minimal, Focal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 38 710 185 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 39 721 185 1 Infiltration Cellular Minimal, Mononuclear Cl Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 1 663 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 2 664 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 3 667 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 5 670 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 6 676 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 7 679 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 8 689 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl Vehicle Control 10 9 722 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 31 671 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 33 686 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 34 687 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 35 691 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 36 706 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 37 709 185 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 38 710 185 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 39 721 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands Submandibul Gl 1000 PPM 10 40 732 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Alimentary System Stomach Glandular, Glands Vehicle Control 10 10 724 184 1 Ectasia Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 1000 PPM 10 36 706 185 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Fascult Vehicle Control 10 3 667 184 1 Hypertrophy Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Fascult 1000 PPM 10 31 671 185 1 Hypertrophy Minimal, Focal Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 1 663 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 2 664 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 3 667 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 4 668 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 5 670 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 6 676 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 7 679 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 8 689 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul Vehicle Control 10 9 722 184 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 31 671 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 32 672 185 1 Degeneration Mild, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 34 687 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 35 691 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 36 706 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 37 709 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 38 710 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 39 721 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Endocrine System Adrenal Cortex Zona Reticul 1000 PPM 10 40 732 185 1 Degeneration Minimal, Fatty Terminal Sacrifice
Hematopoietic System Thymus 1000 PPM 10 32 672 185 1 Hemorrhage Minimal, Acute Terminal Sacrifice
Hematopoietic System Thymus 1000 PPM 10 38 710 185 1 Hemorrhage Minimal, Focal, Acute Terminal Sacrifice
Respiratory System Lung Alveolus Vehicle Control 10 10 724 184 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung Alveolus Vehicle Control 10 6 676 184 1 Infiltration Cellular Minimal, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 663 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 10 724 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 664 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 3 667 184 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 4 668 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 5 670 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 6 676 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 7 679 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 8 689 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 31 671 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 32 672 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 33 686 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 34 687 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 35 691 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 38 710 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 39 721 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 40 732 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 1000 PPM 10 39 721 185 1 Inflammation Minimal, Focal, Suppurative, Acute Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 PPM 10 37 709 185 1 Degeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney Renal Tubule Vehicle Control 10 3 667 184 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule Vehicle Control 10 10 724 184 1 Regeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney Renal Tubule Vehicle Control 10 3 667 184 1 Regeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 PPM 10 31 671 185 1 Regeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 PPM 10 35 691 185 1 Regeneration Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 PPM 10 37 709 185 1 Regeneration Minimal, Focal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 5 670 184 1 Casts Protein Minimal, Focal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 39 721 185 1 Casts Protein Minimal, Focal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 663 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 664 184 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 3 667 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 5 670 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 6 676 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 7 679 184 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 8 689 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 9 722 184 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 31 671 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 32 672 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 33 686 185 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 34 687 185 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 35 691 185 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 38 710 185 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 40 732 185 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice