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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 2,4-Decadienal
CASRN: ="25152-84-5"
Study Number: C93022B
Exposure Route: GAVAGE
TDMS Number: 9302203
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Duodenum 800 MG/KG/DY 10 11 54 94 1 Erosion Mild, Focal Terminal Sacrifice
Alimentary System Intestine Small Duodenum 800 MG/KG/DY 10 11 54 94 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 2 9 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 2 7 94 1 Infiltration Cellular Mild, Mixed Cell Terminal Sacrifice
Alimentary System Liver 800 MG/KG/DY 10 11 51 94 1 Infiltration Cellular Mild, Mixed Cell Terminal Sacrifice
Alimentary System Stomach Forestomach 400 MG/KG/DY 10 10 46 94 1 Edema Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 400 MG/KG/DY 10 10 49 94 1 Edema Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 400 MG/KG/DY 10 10 49 94 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 400 MG/KG/DY 10 9 41 94 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 11 51 94 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 11 53 94 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 400 MG/KG/DY 10 10 46 94 1 Degeneration Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 51 94 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 52 94 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 53 94 1 Degeneration Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 54 94 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 55 94 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 400 MG/KG/DY 10 10 46 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 400 MG/KG/DY 10 10 50 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 400 MG/KG/DY 10 9 42 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 400 MG/KG/DY 10 9 43 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 51 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 52 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 54 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 11 55 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 12 56 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 12 59 94 1 Hyperplasia Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 2 94 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 3 94 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 8 94 1 Cardiomyopathy Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 2 10 94 1 Accessory Adrenal Cortical Nodule Moderate Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 10 1 5 94 1 Cyst Mild Terminal Sacrifice
Endocrine System Thyroid Gland 800 MG/KG/DY 10 12 60 94 1 Ultimobranchial Cyst Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 1 1 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 1 2 94 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 1 3 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 1 4 94 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 2 10 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 2 7 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 2 9 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 800 MG/KG/DY 10 11 52 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 800 MG/KG/DY 10 11 53 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 800 MG/KG/DY 10 11 55 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 800 MG/KG/DY 10 12 59 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 10 1 4 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Thymus 400 MG/KG/DY 1 9 44 94 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Thymus 800 MG/KG/DY 10 11 51 94 1 Hemorrhage Moderate Terminal Sacrifice
Hematopoietic System Thymus 800 MG/KG/DY 10 12 60 94 1 Hemorrhage Minimal Terminal Sacrifice
Integumentary System Skin 400 MG/KG/DY 1 10 46 94 1 Inflammation Mild, Chronic Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 1 94 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 4 94 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 10 94 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 6 94 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung 800 MG/KG/DY 10 11 51 94 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 800 MG/KG/DY 10 12 58 94 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 800 MG/KG/DY 10 12 60 94 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 6 94 1 Infiltration Cellular Minimal, Histiocyte Terminal Sacrifice
Respiratory System Lung 800 MG/KG/DY 10 12 60 94 1 Metaplasia, Osseous Minimal, Osseous Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 9 8 39 94 1 Atrophy Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 9 41 94 1 Atrophy Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 12 57 94 1 Atrophy Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 12 58 94 1 Atrophy Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 12 59 94 1 Atrophy Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 12 60 94 1 Atrophy Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 9 8 39 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Respirat Epith 800 MG/KG/DY 10 12 56 94 1 Hyperplasia Minimal Terminal Sacrifice
Respiratory System Nose Sinus 200 MG/KG/DY 9 8 39 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose Turbinate 200 MG/KG/DY 9 8 39 94 1 Osteofibrosis Minimal Terminal Sacrifice
Respiratory System Nose Turbinate 400 MG/KG/DY 10 9 41 94 1 Osteofibrosis Minimal Terminal Sacrifice
Respiratory System Nose Turbinate 800 MG/KG/DY 10 11 53 94 1 Osteofibrosis Minimal Terminal Sacrifice
Respiratory System Nose Turbinate 800 MG/KG/DY 10 11 55 94 1 Osteofibrosis Minimal Terminal Sacrifice
Respiratory System Nose Turbinate 800 MG/KG/DY 10 12 59 94 1 Osteofibrosis Minimal Terminal Sacrifice
Respiratory System Nose 400 MG/KG/DY 10 9 41 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 400 MG/KG/DY 10 9 45 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 11 53 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 11 54 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 12 56 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 12 57 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 12 58 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 12 59 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Nose Vehicle Control 10 2 10 94 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Nose 800 MG/KG/DY 10 12 56 94 1 Inflammation Minimal, Chronic Terminal Sacrifice