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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 2,4-Decadienal
CASRN: ="25152-84-5"
Study Number: C93022B
Exposure Route: GAVAGE
TDMS Number: 9302204
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus 800 MG/KG/DY 10 71 111 10 1 Inflammation Moderate, Acute Dosing Accident
Alimentary System Esophagus 800 MG/KG/DY 10 71 115 94 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Esophagus 100 MG/KG/DY 1 65 85 8 1 Perforation Moderate Dosing Accident
Alimentary System Esophagus 800 MG/KG/DY 10 71 111 10 1 Perforation Moderate Dosing Accident
Alimentary System Liver 800 MG/KG/DY 10 71 111 10 1 Necrosis Minimal, Focal Dosing Accident
Alimentary System Salivary Glands 800 MG/KG/DY 10 71 115 94 1 Inflammation Mild, Suppurative Terminal Sacrifice
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 71 111 10 1 Hyperkeratosis Moderate Dosing Accident
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 71 111 10 1 Inflammation Mild, Acute Dosing Accident
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 71 114 94 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 72 116 94 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Stomach Forestomach 800 MG/KG/DY 10 72 118 94 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 400 MG/KG/DY 10 69 102 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 71 111 10 1 Hyperplasia Moderate Dosing Accident
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 71 114 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 72 116 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 800 MG/KG/DY 10 72 118 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Glandular 800 MG/KG/DY 10 71 114 94 1 Inflammation Mild, Acute Terminal Sacrifice
Alimentary System Stomach Glandular 800 MG/KG/DY 10 71 114 94 1 Ulcer Mild Terminal Sacrifice
Cardiovascular System Heart Atrium 100 MG/KG/DY 1 65 85 8 1 Inflammation Mild, Acute Dosing Accident
Endocrine System Parathyroid Gland 800 MG/KG/DY 10 72 119 94 1 Cyst Minimal Terminal Sacrifice
Hematopoietic System Thymus 100 MG/KG/DY 1 65 85 8 1 Necrosis Mild, Lymphoid Dosing Accident
Musculoskeletal System Bone Femur 800 MG/KG/DY 10 71 111 10 1 Fibrous Osteodystrophy Mild Dosing Accident
Respiratory System Lung Mediastinum 100 MG/KG/DY 1 65 85 8 1 Necrosis Mild Dosing Accident
Respiratory System Lung Perivascular 800 MG/KG/DY 10 71 115 94 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung 800 MG/KG/DY 10 71 111 10 1 Inflammation Mild, Acute Dosing Accident
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 69 102 94 1 Atrophy Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 70 110 94 1 Atrophy Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 71 113 94 1 Atrophy Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 100 MG/KG/DY 10 65 83 94 1 Degeneration Minimal, Hydropic Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 10 67 91 94 1 Necrosis Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 10 67 92 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 10 67 94 94 1 Necrosis Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 10 67 95 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 10 68 96 94 1 Necrosis Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 200 MG/KG/DY 10 68 99 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 69 102 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 69 105 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 70 107 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 70 109 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 400 MG/KG/DY 10 70 110 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 71 113 94 1 Necrosis Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 800 MG/KG/DY 10 72 116 94 1 Necrosis Moderate Terminal Sacrifice
Respiratory System Nose Respirat Epith, Sinus 800 MG/KG/DY 10 71 113 94 1 Metaplasia Moderate, Squamous Terminal Sacrifice
Respiratory System Nose Sinus 800 MG/KG/DY 10 71 113 94 1 Inflammation Minimal, Acute Terminal Sacrifice