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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 2,4-Hexadienal
CASRN: ="142-83-6"
Study Number: C93023B
Exposure Route: GAVAGE
TDMS Number: 9302303
Sex: Female
Strain and Species: F 344/N Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 13 63 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 13 64 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 30 MG/KG/DY 2 20 97 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 30 MG/KG/DY 2 20 98 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 60 MG/KG/DY 3 21 102 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 60 MG/KG/DY 3 22 106 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 60 MG/KG/DY 3 22 110 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 24 116 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 24 117 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 24 118 94 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 13 61 94 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 13 62 94 1 Infiltration Cellular Moderate, Mixed Cell Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 13 65 94 1 Infiltration Cellular Mild, Mixed Cell Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 14 70 94 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 23 113 94 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 23 114 94 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 23 115 94 1 Infiltration Cellular Minimal, Mixed Cell Terminal Sacrifice
Alimentary System Liver 120 MG/KG/DY 10 24 119 94 1 Infiltration Cellular Mild, Mixed Cell Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 23 113 94 1 Foreign Body Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 24 120 94 1 Foreign Body Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 23 112 94 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 23 113 94 1 Inflammation Moderate, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 23 115 94 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 24 119 94 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach 120 MG/KG/DY 10 24 120 94 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 113 94 1 Degeneration Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 115 94 1 Degeneration Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 117 94 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 120 94 1 Degeneration Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 111 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 112 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 113 94 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 114 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 23 115 94 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 116 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 117 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 118 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 119 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 24 120 94 1 Hyperplasia Marked Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 14 70 94 1 Cardiomyopathy Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 14 67 94 1 Accessory Adrenal Cortical Nodule Moderate Terminal Sacrifice
Endocrine System Adrenal Cortex 120 MG/KG/DY 10 23 112 94 1 Accessory Adrenal Cortical Nodule Moderate Terminal Sacrifice
Endocrine System Pituitary Gland Pars Distalis Vehicle Control 10 13 61 94 1 Cyst Moderate Terminal Sacrifice
Endocrine System Thyroid Gland Vehicle Control 10 13 63 94 1 Ultimobranchial Cyst Moderate Terminal Sacrifice
Genital System Ovary Vehicle Control 10 13 63 94 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary Vehicle Control 10 14 67 94 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary 30 MG/KG/DY 1 20 96 94 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary 60 MG/KG/DY 3 21 102 94 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary 60 MG/KG/DY 3 21 103 94 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary 60 MG/KG/DY 3 21 104 94 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary 120 MG/KG/DY 10 24 118 94 1 Cyst Moderate Terminal Sacrifice
Genital System Uterus Vehicle Control 10 13 64 94 1 Hydrometra Marked Terminal Sacrifice
Genital System Uterus Vehicle Control 10 14 66 94 1 Hydrometra Mild Terminal Sacrifice
Genital System Uterus Vehicle Control 10 14 69 94 1 Hydrometra Mild Terminal Sacrifice
Genital System Uterus 30 MG/KG/DY 2 20 96 94 1 Hydrometra Moderate Terminal Sacrifice
Genital System Uterus 30 MG/KG/DY 2 20 98 94 1 Hydrometra Moderate Terminal Sacrifice
Genital System Uterus 60 MG/KG/DY 2 22 106 94 1 Hydrometra Moderate Terminal Sacrifice
Genital System Uterus 60 MG/KG/DY 2 22 110 94 1 Hydrometra Moderate Terminal Sacrifice
Genital System Uterus 120 MG/KG/DY 10 24 117 94 1 Hydrometra Moderate Terminal Sacrifice
Genital System Uterus 120 MG/KG/DY 10 24 120 94 1 Hydrometra Moderate Terminal Sacrifice
Hematopoietic System Bone Marrow 120 MG/KG/DY 10 23 115 94 1 Infiltration Cellular Mild, Histiocyte Terminal Sacrifice
Hematopoietic System Bone Marrow 120 MG/KG/DY 10 24 118 94 1 Infiltration Cellular Mild, Histiocyte Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 13 65 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 14 70 94 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 120 MG/KG/DY 10 24 116 94 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 60 MG/KG/DY 10 21 105 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 23 113 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 24 120 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose 7.5 MG/KG/DY 10 15 73 94 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 14 68 94 1 Inflammation Mild, Chronic Active Terminal Sacrifice