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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 2,4-Hexadienal
CASRN: ="142-83-6"
Study Number: C93023B
Exposure Route: GAVAGE
TDMS Number: 9302304
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus Muscularis Vehicle Control 10 10 10 6 1 Necrosis Mild Dosing Accident
Alimentary System Esophagus Muscularis Vehicle Control 10 5 5 85 1 Necrosis Moderate Dosing Accident
Alimentary System Esophagus Muscularis 60 MG/KG/DY 1 46 46 4 1 Necrosis Mild Dosing Accident
Alimentary System Esophagus 60 MG/KG/DY 1 46 46 4 1 Inflammation Mild, Focal, Suppurative Dosing Accident
Alimentary System Esophagus Vehicle Control 10 5 5 85 1 Perforation Moderate Dosing Accident
Alimentary System Stomach Forestomach Vehicle Control 10 1 1 94 1 Inflammation Mild, Chronic Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium Vehicle Control 10 10 10 6 1 Hyperplasia Mild Dosing Accident
Alimentary System Stomach Forestomach, Epithelium Vehicle Control 10 1 1 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 52 52 94 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 53 53 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 120 MG/KG/DY 10 58 58 94 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium Vehicle Control 10 10 10 6 1 Ulcer Mild Dosing Accident
Alimentary System Stomach Glandular, Epithelium Vehicle Control 10 10 10 6 1 Degeneration Mild, Cystic Dosing Accident
Endocrine System Parathyroid Gland 120 MG/KG/DY 10 54 54 94 1 Cyst Minimal Terminal Sacrifice
Genital System Testes Germinal Epith 60 MG/KG/DY 2 47 47 94 1 Degeneration Moderate Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 10 10 10 6 1 Necrosis Moderate, Lymphoid Dosing Accident
Hematopoietic System Thymus Vehicle Control 10 10 10 6 1 Atrophy Moderate Dosing Accident
Hematopoietic System Thymus 60 MG/KG/DY 1 46 46 4 1 Atrophy Marked Dosing Accident
Hematopoietic System Thymus Vehicle Control 10 5 5 85 1 Necrosis Moderate, Lymphoid Dosing Accident
Integumentary System Skin Subcut Tiss Vehicle Control 10 10 10 6 1 Foreign Body Mild Dosing Accident
Integumentary System Skin Subcut Tiss Vehicle Control 10 10 10 6 1 Necrosis Moderate, Fatty Dosing Accident
Musculoskeletal System Skeletal Muscle Vehicle Control 1 10 10 6 1 Necrosis Mild, Focal Dosing Accident
Respiratory System Lung Mediastinum Vehicle Control 10 10 10 6 1 Foreign Body Mild Dosing Accident
Respiratory System Lung Mediastinum Vehicle Control 10 5 5 85 1 Inflammation Moderate, Suppurative Dosing Accident
Respiratory System Lung Mediastinum 60 MG/KG/DY 1 46 46 4 1 Inflammation Moderate, Suppurative Dosing Accident
Respiratory System Lung 60 MG/KG/DY 1 46 46 4 1 Foreign Body Mild Dosing Accident
Respiratory System Lung Vehicle Control 10 10 10 6 1 Necrosis Mild Dosing Accident
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 52 52 94 1 Atrophy Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 53 53 94 1 Atrophy Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 54 54 94 1 Atrophy Moderate Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 58 58 94 1 Atrophy Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 52 52 94 1 Necrosis Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 53 53 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 54 54 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 55 55 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 120 MG/KG/DY 10 58 58 94 1 Necrosis Minimal Terminal Sacrifice
Respiratory System Nose Vomeronas Org 120 MG/KG/DY 10 51 51 94 1 Cyst Mild Terminal Sacrifice
Respiratory System Nose Vomeronas Org 60 MG/KG/DY 10 46 46 4 1 Degeneration Mild, Cystic Dosing Accident
Respiratory System Nose 120 MG/KG/DY 10 54 54 94 1 Exudate Minimal Terminal Sacrifice
Respiratory System Pleura 60 MG/KG/DY 1 46 46 4 1 Inflammation Mild, Suppurative Dosing Accident