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Long-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 2-Chloro-p-phenylenediamine sulfate
CASRN: ="61702-44-1"
Study Number: C03316
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Gall bladder Untreated Control 16 NA 3_018 114.00 1 Inflammation, Nos Scheduled Sacrifice
Alimentary System Intestine Small Duodenum 6000 PPM 36 NA 2_035 111.00 1 Amyloidosis Scheduled Sacrifice
Alimentary System Intestine Small Ileum, Ileum 6000 PPM 35 NA 2_035 111.00 1 Amyloidosis Scheduled Sacrifice
Alimentary System Intestine Small Jejunum 6000 PPM 37 NA 2_035 111.00 1 Amyloidosis Scheduled Sacrifice
Alimentary System Intestine Small Peyers Patch Untreated Control NA NA 3_015 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_026 111.00 1 Hematopoiesis Natural Death
Alimentary System Liver 3000 PPM 49 NA 1_039 111.00 1 Hyperplasia, Focal Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_015 111.00 1 Hematopoiesis Scheduled Sacrifice
Alimentary System Liver 6000 PPM 44 NA 2_042 111.00 1 Hyperplasia, Focal Scheduled Sacrifice
Alimentary System Pancreas Acinus 3000 PPM 44 NA 1_032 111.00 1 Atrophy, Nos Scheduled Sacrifice
Alimentary System Pancreas Acinus 6000 PPM 40 NA 2_032 111.00 1 Atrophy, Nos Scheduled Sacrifice
Alimentary System Pancreas 3000 PPM 44 NA 1_032 111.00 1 Inflammation, Chronic Scheduled Sacrifice
Alimentary System Stomach 3000 PPM 48 NA 1_031 111.00 1 Abscess, Nos Scheduled Sacrifice
Alimentary System Stomach 3000 PPM 48 NA 1_043 111.00 1 Abscess, Nos Scheduled Sacrifice
Alimentary System Stomach 6000 PPM 40 NA 2_043 111.00 1 Abscess, Nos Natural Death
All Others Unspecified Ear 6000 PPM NA NA 2_012 111.00 1 Cholesteatoma Moribund Sacrifice
All Others Unspecified Multiple Organs Nos Untreated Control NA NA 3_011 114.00 1 Amyloidosis Scheduled Sacrifice
Cardiovascular System Heart 6000 PPM 43 NA 2_035 111.00 1 Amyloidosis Scheduled Sacrifice
Endocrine System Adrenal gland Capsule Untreated Control 18 NA 3_001 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Endocrine System Adrenal gland Capsule Untreated Control 18 NA 3_003 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Endocrine System Adrenal gland Capsule Untreated Control 18 NA 3_018 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Endocrine System Adrenal gland Capsule 3000 PPM 46 NA 1_035 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Endocrine System Adrenal gland Cortex Nos Untreated Control 18 NA 3_009 114.00 1 Hypertrophy, Focal Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_005 114.00 1 Cyst, Follicular Nos Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_012 114.00 1 Hyperplasia, Follicular Cell Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_015 114.00 1 Hyperplasia, Follicular Cell Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_020 114.00 1 Hyperplasia, Follicular Cell Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_040 111.00 1 Mineralization Moribund Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_010 111.00 1 Cyst, Nos Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_034 111.00 1 Cyst, Nos Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_035 111.00 1 Cyst, Nos Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_043 111.00 1 Cyst, Nos Scheduled Sacrifice
Genital System Ovary 3000 PPM 39 NA 1_046 111.00 1 Degeneration, Cystic Scheduled Sacrifice
Genital System Ovary 6000 PPM 38 NA 2_035 111.00 1 Amyloidosis Scheduled Sacrifice
Genital System Uterus Endometrium Untreated Control 17 NA 3_006 114.00 1 Hyperplasia, Nos Natural Death
Genital System Uterus Endometrium Untreated Control 17 NA 3_001 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Genital System Uterus Endometrium Untreated Control 17 NA 3_003 114.00 1 Hyperplasia, Cystic Scheduled Sacrifice
Genital System Uterus Endometrium Untreated Control 17 NA 3_014 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Genital System Uterus Endometrium Untreated Control 17 NA 3_017 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Genital System Uterus Endometrium Untreated Control 17 NA 3_018 114.00 1 Hyperplasia, Nos Scheduled Sacrifice
Genital System Uterus Endometrium 3000 PPM 47 NA 1_013 111.00 1 Hyperplasia, Cystic Scheduled Sacrifice
Genital System Uterus Endometrium 3000 PPM 47 NA 1_030 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Genital System Uterus Endometrium 3000 PPM 47 NA 1_038 111.00 1 Hyperplasia, Cystic Scheduled Sacrifice
Genital System Uterus Endometrium 6000 PPM 38 NA 2_033 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Genital System Uterus Fallopian Tube 6000 PPM 38 NA 2_022 111.00 1 Degeneration, Nos Scheduled Sacrifice
Genital System Uterus Untreated Control 17 NA 3_002 114.00 1 Inflammation, Nos Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 3000 PPM 46 NA 1_005 111.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 6000 PPM 43 NA 2_021 111.00 1 Hematopoiesis Moribund Sacrifice
Hematopoietic System Spleen Follicles 3000 PPM 49 NA 1_037 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 18 NA 3_004 114.00 1 Hematopoiesis Moribund Sacrifice
Hematopoietic System Spleen Untreated Control 18 NA 3_014 114.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen 3000 PPM 49 NA 1_004 111.00 1 Hematopoiesis Natural Death
Hematopoietic System Spleen 3000 PPM 49 NA 1_008 111.00 1 Hematopoiesis Natural Death
Hematopoietic System Spleen 3000 PPM 49 NA 1_022 111.00 1 Hyperplasia, Lymphoid Natural Death
Hematopoietic System Spleen 3000 PPM 49 NA 1_026 111.00 1 Hematopoiesis Natural Death
Hematopoietic System Spleen 3000 PPM 49 NA 1_029 111.00 1 Hematopoiesis Natural Death
Hematopoietic System Spleen 6000 PPM 43 NA 2_015 111.00 1 Hematopoiesis Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 1_026 111.00 1 Inflammation, Nos Natural Death
Respiratory System Lung 3000 PPM 49 NA 1_011 111.00 1 Inflammation, Focal Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 1_020 111.00 1 Inflammation, Nos Scheduled Sacrifice
Respiratory System Lung 3000 PPM 49 NA 1_032 111.00 1 Inflammation, Nos Scheduled Sacrifice
Urinary System Kidney 3000 PPM 49 NA 1_015 111.00 1 Glomerulosclerosis, Nos Scheduled Sacrifice
Urinary System Kidney 6000 PPM 43 NA 2_035 111.00 1 Amyloidosis Scheduled Sacrifice
Urinary System Kidney 6000 PPM 43 NA 2_035 111.00 1 Inflammation, Nos Scheduled Sacrifice