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Long-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 2-Chloro-p-phenylenediamine sulfate
CASRN: ="61702-44-1"
Study Number: C03316
Exposure Route: Dosed-Feed
TDMS Number:
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Weeks on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Gall bladder 3000 PPM 30 NA 1_029 111.00 1 Calculus, Unknown Gross Or Micro Moribund Sacrifice
Alimentary System Liver Bile Duct 3000 PPM 30 NA 1_006 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Alimentary System Liver Bile Duct 3000 PPM 30 NA 1_043 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Alimentary System Liver Bile Duct 6000 PPM 34 NA 2_006 111.00 1 Hyperplasia, Nos Scheduled Sacrifice
Alimentary System Liver Untreated Control 17 NA 3_002 113.00 1 Necrosis, Coagulative Natural Death
Alimentary System Liver 3000 PPM 49 NA 1_029 111.00 1 Inflammation, Nos Moribund Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_026 111.00 1 Necrosis, Focal Natural Death
Alimentary System Liver 3000 PPM 49 NA 1_006 111.00 1 Hyperplasia, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_011 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_012 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_024 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_028 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_032 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_033 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_034 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_038 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_042 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_043 111.00 1 Inflammation, Acute Scheduled Sacrifice
Alimentary System Liver 3000 PPM 49 NA 1_050 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 6000 PPM 46 NA 2_001 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Liver 6000 PPM 46 NA 2_006 111.00 1 Hematopoiesis Scheduled Sacrifice
Alimentary System Liver 6000 PPM 46 NA 2_006 111.00 1 Hyperplasia, Focal Scheduled Sacrifice
Alimentary System Liver 6000 PPM 46 NA 2_010 111.00 1 Necrosis, Focal Scheduled Sacrifice
Alimentary System Pancreas Acinus Untreated Control 16 NA 3_007 113.00 1 Atrophy, Nos Scheduled Sacrifice
Alimentary System Stomach 3000 PPM 47 NA 1_032 111.00 1 Abscess, Nos Scheduled Sacrifice
Alimentary System Stomach 3000 PPM 47 NA 1_040 111.00 1 Abscess, Nos Scheduled Sacrifice
All Others Unspecified Multiple Organs Nos 3000 PPM NA NA 1_029 111.00 1 Hematopoiesis Moribund Sacrifice
Cardiovascular System Heart Cardiovascular System 3000 PPM NA NA 1_004 111.00 1 Perivasculitis Scheduled Sacrifice
Endocrine System Thyroid Untreated Control 17 NA 3_001 113.00 1 Hyperplasia, Follicular Cell Scheduled Sacrifice
Endocrine System Thyroid 3000 PPM 47 NA 1_027 111.00 1 Cyst, Follicular Nos Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node Untreated Control 17 NA 3_001 113.00 1 Congestion, Nos Scheduled Sacrifice
Hematopoietic System Lymph node Mesenteric Lymph Node 3000 PPM 50 NA 1_034 111.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 16 NA 3_007 113.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen Untreated Control 16 NA 3_017 113.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen 3000 PPM 50 NA 1_029 111.00 1 Hyperplasia, Nos Moribund Sacrifice
Hematopoietic System Spleen 3000 PPM 50 NA 1_004 111.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen 3000 PPM 50 NA 1_010 111.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen 3000 PPM 50 NA 1_033 111.00 1 Hematopoiesis Scheduled Sacrifice
Hematopoietic System Spleen 6000 PPM 45 NA 2_028 111.00 1 Hematopoiesis Scheduled Sacrifice
Respiratory System Lung 3000 PPM 50 NA 1_029 111.00 1 Pneumonia, Chronic Murine Moribund Sacrifice
Respiratory System Lung 3000 PPM 50 NA 1_007 111.00 1 Inflammation, Nos Scheduled Sacrifice
Urinary System Kidney 3000 PPM 50 NA 1_002 111.00 1 Mineralization Scheduled Sacrifice