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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 3,3',4,4'-Tetrachloroazobenzene
CASRN: ="14047-09-7"
Study Number: C88148
Exposure Route: GAVAGE
TDMS Number: 8814801
Sex: Female
Strain and Species: F 344/N Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 12.5 MG/KG 1 8 40 17 1 Hepatodiaphragmatic Nodule Minimal Terminal Sacrifice
Alimentary System Liver 200 MG/KG 1 11 52 17 1 Hepatodiaphragmatic Nodule Mild Terminal Sacrifice
Genital System Ovary 500 MG/KG 1 12 57 17 1 Cyst Mild Terminal Sacrifice
Hematopoietic System Spleen 12.5 MG/KG 5 8 38 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 9 41 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 9 43 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 9 44 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 9 45 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 10 46 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 10 47 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 10 48 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 10 49 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 10 50 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 11 51 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 11 52 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 11 53 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 11 54 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 11 55 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 12 56 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 12 57 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 12 58 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 12 59 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 12 60 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 500 MG/KG 5 12 56 17 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus Vehicle Control 5 7 32 17 1 Hemorrhage Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 7 32 17 1 Mineralization Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 7 34 17 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 12 57 17 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 12 60 17 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 7 31 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 7 32 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 7 33 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 7 35 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 12 56 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 12 58 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 12 59 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice