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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 3,3',4,4'-Tetrachloroazobenzene
CASRN: ="14047-09-7"
Study Number: C88148
Exposure Route: GAVAGE
TDMS Number: 8814801
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 200 MG/KG 1 5 23 17 1 Hepatodiaphragmatic Nodule Mild Terminal Sacrifice
Hematopoietic System Spleen 12.5 MG/KG 5 2 10 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 12.5 MG/KG 5 2 6 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 12.5 MG/KG 5 2 7 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 12.5 MG/KG 5 2 9 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 3 11 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 3 12 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 3 13 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 3 14 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 32 MG/KG 5 3 15 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 4 16 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 4 17 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 4 18 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 4 19 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 80 MG/KG 5 4 20 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 5 21 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 5 22 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 5 23 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 5 24 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 200 MG/KG 5 5 25 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 6 26 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 6 27 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 6 28 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 6 29 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 500 MG/KG 5 6 30 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Thymus 500 MG/KG 5 6 29 17 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Thymus 500 MG/KG 5 6 30 17 1 Hemorrhage Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule Vehicle Control 5 1 5 17 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 80 MG/KG 5 4 18 17 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 80 MG/KG 5 4 20 17 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 200 MG/KG 5 5 24 17 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 500 MG/KG 5 6 26 17 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Renal Tubule 500 MG/KG 5 6 27 17 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Renal Tubule 500 MG/KG 5 6 28 17 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 500 MG/KG 5 6 29 17 1 Accumulation, Hyaline Droplet Mild Terminal Sacrifice
Urinary System Kidney Renal Tubule 500 MG/KG 5 6 30 17 1 Accumulation, Hyaline Droplet Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 5 1 3 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Urinary System Kidney 12.5 MG/KG 5 2 10 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 12.5 MG/KG 5 2 9 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 32 MG/KG 5 3 13 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 80 MG/KG 5 4 16 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 80 MG/KG 5 4 17 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 80 MG/KG 5 4 20 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 200 MG/KG 5 5 22 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 200 MG/KG 5 5 24 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 200 MG/KG 5 5 25 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 6 27 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 6 28 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 6 29 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice
Urinary System Kidney 500 MG/KG 5 6 30 17 1 Nephropathy Minimal, Chronic Terminal Sacrifice