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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 3,3',4,4'-Tetrachloroazobenzene
CASRN: ="14047-09-7"
Study Number: C88148
Exposure Route: GAVAGE
TDMS Number: 8814803
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 3 MG/KG 10 8 39 92 1 Hepatodiaphragmatic Nodule Mild Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 1 2 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Mesentery Fat 30 MG/KG 1 12 59 92 1 Hemorrhage Mild, Focal Terminal Sacrifice
Alimentary System Mesentery Fat 30 MG/KG 1 12 59 92 1 Necrosis Mild, Focal Terminal Sacrifice
Alimentary System Pancreas Acinus 30 MG/KG 10 11 54 92 1 Atrophy Minimal, Focal Accidentally Killed
Alimentary System Pancreas Acinus 30 MG/KG 10 11 55 92 1 Atrophy Minimal, Focal Terminal Sacrifice
Alimentary System Pancreas Acinus 30 MG/KG 10 12 58 92 1 Atrophy Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 3 MG/KG 10 7 32 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 3 MG/KG 10 7 33 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 3 MG/KG 10 8 37 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 3 MG/KG 10 8 39 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 10 47 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 10 50 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 9 44 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 11 51 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 11 52 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 11 55 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 12 56 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 12 57 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 12 58 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 12 59 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 12 60 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 2 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 4 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 5 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 10 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 6 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 8 92 1 Cardiomyopathy Mild Terminal Sacrifice
Genital System Preputial Gland Bilateral 30 MG/KG 10 12 57 92 1 Cyst Moderate Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 2 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 3 92 1 Inflammation Mild, Focal, Chronic Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 4 92 1 Inflammation Mild, Chronic Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 10 92 1 Inflammation Mild, Chronic Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 6 92 1 Inflammation Mild, Chronic Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 8 92 1 Inflammation Mild, Focal, Chronic Terminal Sacrifice
Genital System Preputial Gland 30 MG/KG 10 11 51 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Genital System Preputial Gland 30 MG/KG 10 11 55 92 1 Inflammation Mild, Chronic Terminal Sacrifice
Hematopoietic System Spleen 3 MG/KG 10 7 32 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 3 MG/KG 10 7 33 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 3 MG/KG 10 8 38 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 10 46 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 10 48 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 10 49 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 10 50 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 9 41 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 9 42 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 9 43 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 9 44 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 11 54 92 1 Hematopoietic Cell Proliferation Mild Accidentally Killed
Hematopoietic System Spleen 30 MG/KG 10 11 51 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 11 52 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 11 53 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 11 55 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 12 56 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 12 57 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 12 58 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 12 59 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 12 60 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 MG/KG 10 10 46 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 MG/KG 10 10 47 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 MG/KG 10 10 49 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 MG/KG 10 9 41 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 10 MG/KG 10 9 42 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 11 54 92 1 Atrophy Mild Accidentally Killed
Hematopoietic System Thymus 30 MG/KG 10 11 51 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 11 52 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 11 53 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 11 55 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 12 56 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 12 57 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 12 58 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 12 59 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 12 60 92 1 Atrophy Mild Terminal Sacrifice
Respiratory System Lung Alveolar Epith Vehicle Control 10 1 1 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Respiratory System Lung Alveolar Epith Vehicle Control 10 1 5 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Respiratory System Lung Alveolar Epith Vehicle Control 10 2 10 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Respiratory System Lung Alveolar Epith Vehicle Control 10 2 7 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Respiratory System Lung Alveolar Epith 30 MG/KG 10 11 54 92 1 Hyperplasia Mild, Focal Accidentally Killed
Respiratory System Lung Alveolar Epith 30 MG/KG 10 12 57 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Respiratory System Lung Alveolar Epith 30 MG/KG 10 12 59 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Respiratory System Lung 10 MG/KG 1 10 50 92 1 Hemorrhage Minimal, Focal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 1 92 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 2 92 1 Infiltration Cellular Minimal, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 2 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 4 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 10 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 10 MG/KG 1 10 50 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 11 54 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Accidentally Killed
Respiratory System Lung 30 MG/KG 10 11 53 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 11 55 92 1 Infiltration Cellular Mild, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 12 57 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 12 58 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 12 59 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 12 60 92 1 Infiltration Cellular Minimal, Focal, Histiocyte Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 2 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 1 3 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 11 53 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 11 55 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 12 57 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 1 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 2 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 3 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 4 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 5 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 10 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 6 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 7 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 8 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 3 11 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 3 12 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 3 13 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 3 14 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 3 15 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 4 16 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 4 17 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 4 18 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 4 19 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 0.1 MG/KG 10 4 20 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 5 21 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 5 22 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 5 23 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 5 24 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 5 25 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 6 26 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 6 27 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 6 28 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 6 29 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 6 30 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 7 31 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 7 32 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 7 33 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 7 34 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 7 35 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 8 36 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 8 37 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 8 38 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 8 39 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 8 40 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 10 46 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 10 47 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 10 48 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 10 49 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 10 50 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 9 41 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 9 42 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 9 43 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 9 44 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 9 45 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 11 54 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 30 MG/KG 10 11 51 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 11 52 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 11 53 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 11 55 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 12 56 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 12 57 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 12 58 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 12 59 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 12 60 92 1 Nephropathy Minimal Terminal Sacrifice