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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 3,3',4,4'-Tetrachloroazoxybenzene
CASRN: ="21232-47-3"
Study Number: C88149
Exposure Route: GAVAGE
TDMS Number: 8814902
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus 100 MG/KG 1 29 29 17 1 Cyst Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 5 1 1 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 5 2 2 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1 MG/KG 5 8 8 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1 MG/KG 5 9 9 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 3.2 MG/KG 5 12 12 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 3.2 MG/KG 5 13 13 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 3.2 MG/KG 5 14 14 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 MG/KG 5 17 17 17 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 MG/KG 5 19 19 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 32 MG/KG 5 21 21 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 32 MG/KG 5 22 22 17 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 26 26 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 27 27 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 28 28 17 1 Inflammation Mild, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 29 29 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 30 30 17 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 5 2 2 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1 MG/KG 5 8 8 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 3.2 MG/KG 5 13 13 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 3.2 MG/KG 5 14 14 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 MG/KG 5 17 17 17 1 Necrosis Mild, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 MG/KG 5 19 19 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 32 MG/KG 5 22 22 17 1 Necrosis Mild, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 26 26 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 27 27 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 28 28 17 1 Necrosis Mild, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 29 29 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Liver Hepatocyte 100 MG/KG 5 30 30 17 1 Necrosis Minimal, Focal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp Vehicle Control 5 5 5 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 1 MG/KG 5 6 6 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 1 MG/KG 5 7 7 17 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 1 MG/KG 5 8 8 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 1 MG/KG 5 9 9 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 3.2 MG/KG 5 13 13 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 3.2 MG/KG 5 14 14 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 10 MG/KG 5 16 16 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 10 MG/KG 5 17 17 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 10 MG/KG 5 18 18 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 32 MG/KG 5 21 21 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 32 MG/KG 5 24 24 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 100 MG/KG 5 26 26 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 100 MG/KG 5 27 27 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 100 MG/KG 5 28 28 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 100 MG/KG 5 29 29 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 100 MG/KG 5 30 30 17 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 10 MG/KG 5 19 19 17 1 Pigmentation Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 100 MG/KG 5 26 26 17 1 Atrophy Mild, Diffuse Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 100 MG/KG 5 27 27 17 1 Atrophy Minimal, Diffuse Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 100 MG/KG 5 28 28 17 1 Atrophy Minimal, Diffuse Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 100 MG/KG 5 29 29 17 1 Atrophy Mild, Diffuse Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 100 MG/KG 5 30 30 17 1 Atrophy Mild, Diffuse Terminal Sacrifice
Hematopoietic System Thymus 32 MG/KG 5 22 22 17 1 Atrophy Minimal Terminal Sacrifice