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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 3,3',4,4'-Tetrachloroazoxybenzene
CASRN: ="21232-47-3"
Study Number: C88149
Exposure Route: GAVAGE
TDMS Number: 8814903
Sex: Female
Strain and Species: F 344/N Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus Muscularis Vehicle Control 10 13 64 92 1 Inflammation Mild, Focal, Chronic Terminal Sacrifice
Alimentary System Esophagus Muscularis 10 MG/KG 10 21 103 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Liver Bile Duct 10 MG/KG 10 22 106 92 1 Hyperplasia Minimal Accidentally Killed
Alimentary System Liver Bile Duct 10 MG/KG 10 22 109 92 1 Hyperplasia Minimal Accidentally Killed
Alimentary System Liver Bile Duct 10 MG/KG 10 22 110 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Liver Bile Duct 30 MG/KG 10 24 118 92 1 Hyperplasia Minimal Accidentally Killed
Alimentary System Liver Bile Duct 30 MG/KG 10 23 114 56 1 Hyperplasia Minimal Moribund Sacrifice
Alimentary System Liver Bile Duct 30 MG/KG 10 24 117 71 1 Hyperplasia Minimal Natural Death
Alimentary System Liver Centrilobular, Hepatocyte 10 MG/KG 10 22 109 92 1 Degeneration Minimal Accidentally Killed
Alimentary System Liver Centrilobular, Hepatocyte 10 MG/KG 10 22 110 92 1 Degeneration Marked Terminal Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 24 118 92 1 Degeneration Minimal Accidentally Killed
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 23 112 65 1 Degeneration Minimal Moribund Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 23 114 56 1 Degeneration Marked Moribund Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 24 116 83 1 Degeneration Mild Moribund Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 23 111 65 1 Degeneration Moderate Natural Death
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 23 113 60 1 Degeneration Marked Natural Death
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 24 117 71 1 Degeneration Moderate Natural Death
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 24 119 80 1 Degeneration Mild Natural Death
Alimentary System Liver Centrilobular, Hepatocyte 30 MG/KG 10 23 115 92 1 Degeneration Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 10 MG/KG 10 21 105 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver 30 MG/KG 10 23 115 92 1 Eosinophilic Focus Minimal Terminal Sacrifice
Alimentary System Liver 10 MG/KG 10 22 107 92 1 Hematopoietic Cell Proliferation Minimal Accidentally Killed
Alimentary System Liver 30 MG/KG 10 23 112 65 1 Hematopoietic Cell Proliferation Minimal Moribund Sacrifice
Alimentary System Liver 30 MG/KG 10 23 114 56 1 Hematopoietic Cell Proliferation Minimal Moribund Sacrifice
Alimentary System Liver 30 MG/KG 10 24 116 83 1 Hematopoietic Cell Proliferation Minimal Moribund Sacrifice
Alimentary System Liver 30 MG/KG 10 23 111 65 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 30 MG/KG 10 23 113 60 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 30 MG/KG 10 24 117 71 1 Hematopoietic Cell Proliferation Minimal Natural Death
Alimentary System Liver 0.1 MG/KG 10 15 71 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 0.1 MG/KG 10 16 80 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 10 MG/KG 10 21 104 92 1 Hepatodiaphragmatic Nodule Accidentally Killed
Alimentary System Liver 30 MG/KG 10 24 116 83 1 Hepatodiaphragmatic Nodule Mild Moribund Sacrifice
Alimentary System Liver 10 MG/KG 10 22 110 92 1 Necrosis Minimal, Focal Terminal Sacrifice
Alimentary System Mesentery Fat 3 MG/KG 1 20 96 92 1 Necrosis Mild Terminal Sacrifice
Alimentary System Pancreas Acinus Vehicle Control 10 13 62 92 1 Atrophy Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 21 101 92 1 Hyperplasia Mild, Focal Accidentally Killed
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 21 104 92 1 Hyperplasia Mild, Focal Accidentally Killed
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 22 106 92 1 Hyperplasia Mild, Focal Accidentally Killed
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 22 107 92 1 Hyperplasia Minimal, Focal Accidentally Killed
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 22 109 92 1 Hyperplasia Mild, Focal Accidentally Killed
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 21 102 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 21 103 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 21 105 92 1 Hyperplasia Moderate, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 22 108 92 1 Hyperplasia Moderate, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 10 MG/KG 10 22 110 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 24 118 92 1 Hyperplasia Minimal, Focal Accidentally Killed
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 23 112 65 1 Hyperplasia Mild, Focal Moribund Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 23 114 56 1 Hyperplasia Mild, Focal Moribund Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 24 116 83 1 Hyperplasia Minimal, Focal Moribund Sacrifice
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 23 111 65 1 Hyperplasia Mild, Focal Natural Death
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 23 113 60 1 Hyperplasia Mild, Focal Natural Death
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 24 117 71 1 Hyperplasia Mild, Focal Natural Death
Alimentary System Stomach Forestomach, Epithelium 30 MG/KG 10 23 115 92 1 Hyperplasia Mild, Focal Terminal Sacrifice
Alimentary System Stomach Glandular 10 MG/KG 10 22 108 92 1 Erosion Mild, Focal Terminal Sacrifice
Cardiovascular System Heart Endocardium 30 MG/KG 10 24 118 92 1 Hemorrhage Mild Accidentally Killed
Cardiovascular System Heart Myocardium Vehicle Control 10 13 61 92 1 Cardiomyopathy Mild Terminal Sacrifice
Cardiovascular System Heart Myocardium Vehicle Control 10 14 66 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium Vehicle Control 10 14 67 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium Vehicle Control 10 14 68 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium Vehicle Control 10 14 70 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 15 72 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 15 73 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 15 74 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 15 75 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 16 76 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 16 77 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 16 78 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 0.1 MG/KG 10 16 79 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 17 81 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 17 82 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 17 83 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 18 86 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 18 88 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 18 89 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 1 MG/KG 10 18 90 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 19 91 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 19 92 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 19 93 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 19 94 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 19 95 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 20 100 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 20 96 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 20 97 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 3 MG/KG 10 20 99 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 10 MG/KG 10 22 106 92 1 Cardiomyopathy Minimal Accidentally Killed
Cardiovascular System Heart Myocardium 10 MG/KG 10 21 103 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 10 MG/KG 10 22 108 92 1 Cardiomyopathy Minimal Terminal Sacrifice
Cardiovascular System Heart Myocardium 30 MG/KG 10 24 118 92 1 Cardiomyopathy Mild Accidentally Killed
Cardiovascular System Heart Myocardium 30 MG/KG 10 24 120 92 1 Cardiomyopathy Mild Accidentally Killed
Cardiovascular System Heart Myocardium 30 MG/KG 10 23 112 65 1 Cardiomyopathy Mild Moribund Sacrifice
Cardiovascular System Heart Myocardium 30 MG/KG 10 23 114 56 1 Cardiomyopathy Moderate Moribund Sacrifice
Cardiovascular System Heart Myocardium 30 MG/KG 10 24 116 83 1 Cardiomyopathy Mild Moribund Sacrifice
Cardiovascular System Heart Myocardium 30 MG/KG 10 23 111 65 1 Cardiomyopathy Moderate Natural Death
Cardiovascular System Heart Myocardium 30 MG/KG 10 23 113 60 1 Cardiomyopathy Moderate Natural Death
Cardiovascular System Heart Myocardium 30 MG/KG 10 24 117 71 1 Cardiomyopathy Moderate Natural Death
Cardiovascular System Heart Myocardium 30 MG/KG 10 24 119 80 1 Cardiomyopathy Mild Natural Death
Cardiovascular System Heart Myocardium 30 MG/KG 10 23 115 92 1 Cardiomyopathy Mild Terminal Sacrifice
Cardiovascular System Heart 10 MG/KG 10 22 109 92 1 Hemorrhage Minimal, Focal Accidentally Killed
Endocrine System Thyroid Gland Vehicle Control 10 14 66 92 1 Ultimobranchial Cyst Minimal, Focal Terminal Sacrifice
Endocrine System Thyroid Gland Vehicle Control 10 14 68 92 1 Ultimobranchial Cyst Minimal, Focal Terminal Sacrifice
Endocrine System Thyroid Gland 10 MG/KG 10 22 107 92 1 Ultimobranchial Cyst Minimal, Focal Accidentally Killed
Endocrine System Thyroid Gland 10 MG/KG 10 22 108 92 1 Ultimobranchial Cyst Minimal, Focal Terminal Sacrifice
Endocrine System Thyroid Gland 30 MG/KG 10 24 120 92 1 Ultimobranchial Cyst Mild, Focal Accidentally Killed
Endocrine System Thyroid Gland 30 MG/KG 10 23 114 56 1 Ultimobranchial Cyst Minimal, Focal Moribund Sacrifice
Endocrine System Thyroid Gland 30 MG/KG 10 24 116 83 1 Ultimobranchial Cyst Minimal, Focal Moribund Sacrifice
Endocrine System Thyroid Gland 30 MG/KG 10 23 113 60 1 Ultimobranchial Cyst Minimal, Focal Natural Death
Endocrine System Thyroid Gland 30 MG/KG 10 23 115 92 1 Ultimobranchial Cyst Minimal, Focal Terminal Sacrifice
Genital System Clitoral Gland Bilateral Vehicle Control 10 14 68 92 1 Inflammation Minimal Terminal Sacrifice
Genital System Clitoral Gland 30 MG/KG 10 23 112 65 1 Atrophy Mild Moribund Sacrifice
Genital System Clitoral Gland 30 MG/KG 10 23 114 56 1 Atrophy Mild Moribund Sacrifice
Genital System Clitoral Gland 30 MG/KG 10 24 116 83 1 Atrophy Mild Moribund Sacrifice
Genital System Clitoral Gland 30 MG/KG 10 23 111 65 1 Atrophy Mild Natural Death
Genital System Clitoral Gland 30 MG/KG 10 23 113 60 1 Atrophy Mild Natural Death
Genital System Clitoral Gland 30 MG/KG 10 24 117 71 1 Atrophy Mild Natural Death
Genital System Clitoral Gland 30 MG/KG 10 24 119 80 1 Atrophy Mild Natural Death
Genital System Clitoral Gland 30 MG/KG 10 23 115 92 1 Atrophy Minimal Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 13 61 92 1 Inflammation Mild, Focal, Chronic Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 13 62 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 13 64 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 10 MG/KG 10 21 104 92 1 Inflammation Minimal, Chronic Active Accidentally Killed
Genital System Clitoral Gland 10 MG/KG 10 22 106 92 1 Inflammation Minimal, Chronic Active Accidentally Killed
Genital System Clitoral Gland 10 MG/KG 10 21 103 92 1 Inflammation Minimal, Focal, Chronic Terminal Sacrifice
Genital System Clitoral Gland 10 MG/KG 10 22 110 92 1 Inflammation Minimal, Acute Terminal Sacrifice
Genital System Clitoral Gland 30 MG/KG 10 23 114 56 1 Inflammation Mild, Acute Moribund Sacrifice
Genital System Ovary Periovarn Tiss 30 MG/KG 10 24 116 83 1 Cyst Mild Moribund Sacrifice
Genital System Uterus Vehicle Control 10 13 63 92 1 Hydrometra Moderate Terminal Sacrifice
Genital System Uterus Vehicle Control 10 13 64 92 1 Hydrometra Mild Terminal Sacrifice
Genital System Uterus Vehicle Control 10 13 65 92 1 Hydrometra Mild Terminal Sacrifice
Genital System Uterus Vehicle Control 10 14 67 92 1 Hydrometra Minimal Terminal Sacrifice
Genital System Uterus 0.1 MG/KG 1 16 80 92 1 Hydrometra Mild Terminal Sacrifice
Genital System Uterus 3 MG/KG 1 19 91 92 1 Hydrometra Mild Terminal Sacrifice
Hematopoietic System Bone Marrow 10 MG/KG 10 21 103 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Bone Marrow 30 MG/KG 10 24 120 92 1 Atrophy Minimal Accidentally Killed
Hematopoietic System Lymph Node Mandibular 3 MG/KG 10 19 91 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 3 MG/KG 10 20 97 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 3 MG/KG 10 20 99 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 30 MG/KG 10 23 111 65 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mandibular 1 MG/KG 10 18 89 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 30 MG/KG 10 23 115 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 30 MG/KG 10 23 114 56 1 Hyperplasia Moderate, Histiocytic Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 23 112 65 1 Atrophy Minimal Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 23 114 56 1 Atrophy Minimal Moribund Sacrifice
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 23 111 65 1 Atrophy Minimal Natural Death
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 23 113 60 1 Atrophy Mild Natural Death
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 23 115 92 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 1 MG/KG 10 17 81 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 1 MG/KG 10 17 85 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 1 MG/KG 10 18 89 92 1 Hyperplasia Mild, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3 MG/KG 10 19 92 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3 MG/KG 10 19 93 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3 MG/KG 10 20 96 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 3 MG/KG 10 20 98 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10 MG/KG 10 21 101 92 1 Hyperplasia Minimal, Histiocytic Accidentally Killed
Hematopoietic System Lymph Node Mesenteric 10 MG/KG 10 21 102 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10 MG/KG 10 21 103 92 1 Hyperplasia Mild, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 24 118 92 1 Hyperplasia Minimal, Histiocytic Accidentally Killed
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 24 120 92 1 Hyperplasia Minimal, Histiocytic Accidentally Killed
Hematopoietic System Lymph Node Mesenteric 30 MG/KG 10 23 115 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic 10 MG/KG 10 21 102 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Spleen 10 MG/KG 10 21 101 92 1 Hematopoietic Cell Proliferation Minimal Accidentally Killed
Hematopoietic System Spleen 10 MG/KG 10 21 104 92 1 Hematopoietic Cell Proliferation Minimal Accidentally Killed
Hematopoietic System Spleen 10 MG/KG 10 22 107 92 1 Hematopoietic Cell Proliferation Minimal Accidentally Killed
Hematopoietic System Spleen 10 MG/KG 10 22 109 92 1 Hematopoietic Cell Proliferation Mild Accidentally Killed
Hematopoietic System Spleen 10 MG/KG 10 21 103 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 24 118 92 1 Hematopoietic Cell Proliferation Mild Accidentally Killed
Hematopoietic System Spleen 30 MG/KG 10 23 112 65 1 Hematopoietic Cell Proliferation Mild Moribund Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 23 114 56 1 Hematopoietic Cell Proliferation Mild Moribund Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 24 116 83 1 Hematopoietic Cell Proliferation Mild Moribund Sacrifice
Hematopoietic System Spleen 30 MG/KG 10 23 111 65 1 Hematopoietic Cell Proliferation Mild Natural Death
Hematopoietic System Spleen 30 MG/KG 10 24 117 71 1 Hematopoietic Cell Proliferation Mild Natural Death
Hematopoietic System Spleen 30 MG/KG 10 23 115 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 14 67 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 14 69 92 1 Pigmentation Minimal Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 3 MG/KG 10 19 91 92 1 Atrophy Minimal Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 21 101 92 1 Atrophy Mild Accidentally Killed
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 21 104 92 1 Atrophy Mild Accidentally Killed
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 22 106 92 1 Atrophy Mild Accidentally Killed
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 22 107 92 1 Atrophy Minimal Accidentally Killed
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 22 109 92 1 Atrophy Mild Accidentally Killed
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 21 102 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 21 103 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 21 105 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 22 108 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 10 MG/KG 10 22 110 92 1 Atrophy Mild Terminal Sacrifice
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 24 118 92 1 Atrophy Marked Accidentally Killed
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 24 120 92 1 Atrophy Moderate Accidentally Killed
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 23 112 65 1 Atrophy Minimal Moribund Sacrifice
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 23 114 56 1 Atrophy Marked Moribund Sacrifice
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 24 116 83 1 Atrophy Marked Moribund Sacrifice
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 23 111 65 1 Atrophy Moderate Natural Death
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 23 113 60 1 Atrophy Marked Natural Death
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 24 117 71 1 Atrophy Moderate Natural Death
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 24 119 80 1 Atrophy Marked Natural Death
Hematopoietic System Thymus Thymocyte 30 MG/KG 10 23 115 92 1 Atrophy Marked Terminal Sacrifice
Hematopoietic System Thymus 30 MG/KG 10 24 118 92 1 Cyst Minimal, Focal Accidentally Killed
Musculoskeletal System Bone Cranium 0.1 MG/KG 1 15 75 92 1 Atrophy Marked Terminal Sacrifice
Nervous System Brain Cerebellum 30 MG/KG 10 23 115 92 1 Hemorrhage Minimal, Focal Terminal Sacrifice
Nervous System Brain Cerebrum 30 MG/KG 10 23 115 92 1 Hemorrhage Minimal, Focal Terminal Sacrifice
Nervous System Brain Cerebrum, Meninges 0.1 MG/KG 1 15 75 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Respiratory System Lung Artery 30 MG/KG 10 23 112 65 1 Inflammation Mild, Chronic Active Moribund Sacrifice
Respiratory System Lung Artery 30 MG/KG 10 23 114 56 1 Inflammation Mild, Chronic Active Moribund Sacrifice
Respiratory System Lung Artery 30 MG/KG 10 24 116 83 1 Inflammation Mild, Chronic Active Moribund Sacrifice
Respiratory System Lung Artery 30 MG/KG 10 23 111 65 1 Inflammation Mild, Chronic Active Natural Death
Respiratory System Lung Artery 30 MG/KG 10 23 113 60 1 Inflammation Mild, Chronic Active Natural Death
Respiratory System Lung Artery 30 MG/KG 10 24 117 71 1 Inflammation Mild, Chronic Active Natural Death
Respiratory System Lung Artery 30 MG/KG 10 24 119 80 1 Inflammation Mild, Chronic Active Natural Death
Respiratory System Lung Artery 30 MG/KG 10 23 115 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Respiratory System Lung Interstitium Vehicle Control 10 13 61 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium Vehicle Control 10 13 62 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium Vehicle Control 10 13 63 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium Vehicle Control 10 13 64 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium Vehicle Control 10 14 66 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 15 71 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 15 72 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 15 73 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 15 74 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 15 75 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 16 76 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 16 77 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 16 78 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 16 79 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 0.1 MG/KG 10 16 80 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 17 81 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 17 82 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 17 83 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 17 84 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 17 85 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 18 86 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 18 87 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 18 88 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 18 89 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 1 MG/KG 10 18 90 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 19 92 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 19 93 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 19 94 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 19 95 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 20 100 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 20 96 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 20 97 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 20 98 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 3 MG/KG 10 20 99 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 10 MG/KG 10 21 101 92 1 Inflammation Minimal, Chronic Accidentally Killed
Respiratory System Lung Interstitium 10 MG/KG 10 21 104 92 1 Inflammation Minimal, Chronic Accidentally Killed
Respiratory System Lung Interstitium 10 MG/KG 10 22 106 92 1 Inflammation Mild, Chronic Accidentally Killed
Respiratory System Lung Interstitium 10 MG/KG 10 22 107 92 1 Inflammation Moderate, Chronic Accidentally Killed
Respiratory System Lung Interstitium 10 MG/KG 10 22 109 92 1 Inflammation Moderate, Chronic Accidentally Killed
Respiratory System Lung Interstitium 10 MG/KG 10 21 102 92 1 Inflammation Mild, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 10 MG/KG 10 21 103 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 10 MG/KG 10 21 105 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 10 MG/KG 10 22 108 92 1 Inflammation Moderate, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 10 MG/KG 10 22 110 92 1 Inflammation Minimal, Chronic Terminal Sacrifice
Respiratory System Lung Interstitium 30 MG/KG 10 24 118 92 1 Inflammation Minimal, Chronic Accidentally Killed
Respiratory System Lung Interstitium 30 MG/KG 10 23 112 65 1 Inflammation Mild, Chronic Moribund Sacrifice
Respiratory System Lung Interstitium 30 MG/KG 10 23 114 56 1 Inflammation Moderate, Chronic Moribund Sacrifice
Respiratory System Lung Interstitium 30 MG/KG 10 24 116 83 1 Inflammation Moderate, Chronic Moribund Sacrifice
Respiratory System Lung Interstitium 30 MG/KG 10 23 111 65 1 Inflammation Moderate, Chronic Natural Death
Respiratory System Lung Interstitium 30 MG/KG 10 23 113 60 1 Inflammation Moderate, Chronic Natural Death
Respiratory System Lung Interstitium 30 MG/KG 10 24 117 71 1 Inflammation Moderate, Chronic Natural Death
Respiratory System Lung Interstitium 30 MG/KG 10 24 119 80 1 Inflammation Mild, Chronic Natural Death
Respiratory System Lung Interstitium 30 MG/KG 10 23 115 92 1 Inflammation Mild, Chronic Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 13 61 92 1 Hemorrhage Minimal, Focal Terminal Sacrifice
Respiratory System Lung 30 MG/KG 10 23 111 65 1 Hemorrhage Minimal, Focal Natural Death
Respiratory System Lung 30 MG/KG 10 24 117 71 1 Hemorrhage Mild, Focal Natural Death
Urinary System Kidney Renal Tubule 30 MG/KG 10 23 114 56 1 Degeneration Moderate Moribund Sacrifice
Urinary System Kidney 0.1 MG/KG 10 15 71 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 18 88 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1 MG/KG 10 18 89 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 19 91 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 19 93 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 19 94 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 20 96 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 20 97 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 3 MG/KG 10 20 98 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 21 101 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 10 MG/KG 10 21 104 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 10 MG/KG 10 22 106 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 10 MG/KG 10 22 109 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 10 MG/KG 10 21 102 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 21 103 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 10 MG/KG 10 22 110 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 30 MG/KG 10 24 118 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 30 MG/KG 10 24 120 92 1 Nephropathy Minimal Accidentally Killed
Urinary System Kidney 30 MG/KG 10 23 112 65 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 30 MG/KG 10 24 116 83 1 Nephropathy Minimal Moribund Sacrifice
Urinary System Kidney 30 MG/KG 10 23 111 65 1 Nephropathy Minimal Natural Death
Urinary System Kidney 30 MG/KG 10 23 113 60 1 Nephropathy Minimal Natural Death
Urinary System Kidney 30 MG/KG 10 24 117 71 1 Nephropathy Minimal Natural Death
Urinary System Kidney 30 MG/KG 10 24 119 80 1 Nephropathy Minimal Natural Death
Urinary System Kidney 30 MG/KG 10 23 115 92 1 Nephropathy Minimal Terminal Sacrifice