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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: 5-(Hydroxymethyl)-2-furfural
CASRN: ="67-47-0"
Study Number: C95011
Exposure Route: GAVAGE
TDMS Number: 9501104
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Esophagus Muscularis Vehicle Control 10 250 250 94 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Esophagus Muscularis 750 MG/KG 10 299 299 94 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Esophagus Periesoph Tiss Vehicle Control 10 249 249 94 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Esophagus Periesoph Tiss 750 MG/KG 10 296 296 94 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 243 243 94 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 247 247 94 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Salivary Glands 750 MG/KG 10 293 293 94 1 Inflammation Minimal Terminal Sacrifice
Cardiovascular System Heart 750 MG/KG 10 298 298 94 1 Ectopic Tissue Mild Terminal Sacrifice
Cardiovascular System Heart 750 MG/KG 10 298 298 94 1 Infiltration Cellular Mild Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 246 246 94 1 Hypertrophy Minimal Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 243 243 94 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung Perivascular Vehicle Control 10 242 242 94 1 Inflammation Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 243 243 94 1 Pigmentation Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 750 MG/KG 10 300 300 94 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Vehicle Control 10 242 242 94 1 Inflammation Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 247 247 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 94 MG/KG 10 269 269 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 273 273 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 274 274 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 275 275 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 277 277 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 278 278 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 280 280 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 281 281 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 282 282 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 284 284 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 285 285 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 286 286 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 288 288 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 289 289 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 290 290 94 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 292 292 93 1 Cytoplasmic Alteration Mild Natural Death
Urinary System Kidney 750 MG/KG 10 291 291 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 293 293 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 294 294 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 295 295 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 296 296 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 297 297 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 298 298 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 299 299 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 300 300 94 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 244 244 94 1 Inflammation Minimal Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 295 295 94 1 Mineralization Minimal Terminal Sacrifice
Urinary System Kidney 188 MG/KG 10 280 280 94 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 375 MG/KG 10 287 287 94 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 750 MG/KG 10 292 292 93 1 Nephropathy Minimal Natural Death