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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Benzyltrimethyl ammonium chloride
CASRN: ="56-93-9"
Study Number: C88139C
Exposure Route: GAVAGE
TDMS Number: 8813906
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular, Hepatocyte Vehicle Control 10 1 1 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte Vehicle Control 10 10 10 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte Vehicle Control 10 7 7 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 100.0 MG/KG 10 41 41 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 100.0 MG/KG 10 46 46 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular, Hepatocyte 100.0 MG/KG 10 50 50 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver 100.0 MG/KG 10 47 47 92 1 Inflammation Minimal, Focal, Chronic Terminal Sacrifice
Alimentary System Salivary Glands Vehicle Control 10 9 9 92 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Endocrine System Adrenal Cortex Capsule 100.0 MG/KG 10 43 43 92 1 Hyperplasia Minimal, Focal Terminal Sacrifice
Genital System Prostate Vehicle Control 10 6 6 92 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic 100.0 MG/KG 10 42 42 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Lymph Follic 100.0 MG/KG 10 49 49 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Spleen Vehicle Control 10 2 2 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 100.0 MG/KG 10 48 48 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice