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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Cupric sulfate
CASRN: ="7758-99-8"
Study Number: C62191B
Exposure Route: DOSED FEED
TDMS Number: 0520605
Sex: Female
Strain and Species: F 344/N Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Intestine Small Jejunum Vehicle Control 10 26 128 92 1 Inflammation Moderate, Acute Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 25 121 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 26 128 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 500 PPM 1 30 148 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 1000 PPM 3 34 169 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 1000 PPM 3 34 170 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 2000 PPM 10 38 186 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 2000 PPM 10 38 187 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 25 121 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 25 125 92 1 Inflammation Minimal, Focal Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 41 203 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 41 204 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 41 205 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 42 206 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 42 207 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 42 210 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 45 221 92 1 Inflammation Moderate, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 45 222 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 45 223 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 45 224 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 45 225 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 46 226 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 46 227 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 46 228 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 46 229 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 46 230 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Mesentery Fat 500 PPM 1 30 148 92 1 Necrosis Moderate Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 26 130 92 1 Atrophy Minimal Terminal Sacrifice
Alimentary System Pancreas 8000 PPM 10 46 226 92 1 Atrophy Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 45 224 92 1 Cyst Epithelial Inclusion Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 37 182 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 37 184 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 37 185 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 38 186 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 38 188 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 38 189 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 38 190 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 41 201 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 41 202 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 41 203 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 41 204 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 41 205 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 42 206 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 42 207 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 42 208 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 42 209 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 42 210 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 45 221 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 45 222 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 45 223 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 45 224 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 45 225 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 46 226 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 46 227 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 46 228 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 46 229 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 46 230 92 1 Hyperplasia Mild Terminal Sacrifice
Cardiovascular System Heart 8000 PPM 10 46 228 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 25 121 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 25 122 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 25 123 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 25 124 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 25 125 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 26 126 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 26 127 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 26 128 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 26 129 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 45 221 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 45 222 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 45 223 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 45 224 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 45 225 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 46 226 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 46 227 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 46 228 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 46 229 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Clitoral Gland 8000 PPM 10 46 230 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Ovary 500 PPM 1 29 143 92 1 Cyst Terminal Sacrifice
Nervous System Brain Vehicle Control 10 26 130 92 1 Gliosis Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 25 124 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Lung 8000 PPM 10 46 227 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 45 221 92 1 Karyomegaly Mild Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 45 222 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 45 223 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 45 224 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 45 225 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 46 226 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 46 227 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 46 228 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 46 229 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 46 230 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 8000 PPM 10 45 221 92 1 Degeneration Mild Terminal Sacrifice
Urinary System Kidney Renal Tubule 8000 PPM 10 45 223 92 1 Degeneration Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 8000 PPM 10 45 224 92 1 Degeneration Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 25 124 92 1 Cyst Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 33 161 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 37 181 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 37 183 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 37 184 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 37 185 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 38 186 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 38 187 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 38 188 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 38 189 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 38 190 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 41 201 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 41 202 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 41 203 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 41 204 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 41 205 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 42 206 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 42 207 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 42 208 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 42 209 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 42 210 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 45 221 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 45 222 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 45 223 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 45 224 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 45 225 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 226 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 227 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 228 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 229 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 230 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 10 30 147 92 1 Mineralization Mild Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 33 162 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 37 184 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 227 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 229 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 45 221 92 1 Pigmentation Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 46 227 92 1 Pigmentation Minimal Terminal Sacrifice