If this is the first time you are viewing this file, please choose 'Save As' from the 'File' menu and resave this file as an Excel file type. This will greatly speed up future viewings of this file.

Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Cupric sulfate
CASRN: ="7758-99-8"
Study Number: C62191B
Exposure Route: DOSED FEED
TDMS Number: 0520605
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 1 5 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 1000 PPM 10 10 50 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 2000 PPM 10 13 62 92 1 Hepatodiaphragmatic Nodule Terminal Sacrifice
Alimentary System Liver 2000 PPM 10 13 64 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 17 81 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 17 82 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 17 83 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 17 84 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 17 85 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 18 86 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 18 87 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 18 88 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 18 89 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 4000 PPM 10 18 90 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 21 101 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 21 102 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 21 103 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 21 104 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 21 105 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 22 106 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 22 107 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 22 108 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 22 109 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Liver 8000 PPM 10 22 110 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 1 2 92 1 Atrophy Minimal Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 1 5 92 1 Atrophy Minimal Terminal Sacrifice
Alimentary System Pancreas 8000 PPM 10 21 104 92 1 Atrophy Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 13 61 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 13 62 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 13 63 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 13 64 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 13 65 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 14 66 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 14 67 92 1 Hyperplasia Minimal Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 14 68 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 14 69 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 2000 PPM 10 14 70 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 17 81 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 17 82 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 17 83 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 17 84 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 17 85 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 18 86 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 18 87 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 18 88 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 18 89 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 4000 PPM 10 18 90 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 21 101 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 21 102 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 21 103 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 21 104 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 21 105 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 22 106 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 22 107 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 22 108 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 22 109 92 1 Hyperplasia Mild Terminal Sacrifice
Alimentary System Stomach Forestomach 8000 PPM 10 22 110 92 1 Hyperplasia Moderate Terminal Sacrifice
Alimentary System Stomach Glandular 1000 PPM 10 10 48 92 1 Mineralization Mild Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 1 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 2 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 3 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 4 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 1 5 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 10 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 6 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 7 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 8 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart Vehicle Control 10 2 9 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart 8000 PPM 10 21 101 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart 8000 PPM 10 21 102 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart 8000 PPM 10 21 103 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart 8000 PPM 10 21 105 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Cardiovascular System Heart 8000 PPM 10 22 108 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Endocrine System Pituitary Gland 8000 PPM 10 21 104 92 1 Cyst Terminal Sacrifice
Genital System Epididymis Vehicle Control 10 2 8 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 2 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 3 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 1 5 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 10 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 7 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 8 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland Vehicle Control 10 2 9 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 21 101 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 21 102 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 21 103 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 21 104 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 21 105 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 22 106 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 22 107 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Preputial Gland 8000 PPM 10 22 108 92 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Genital System Prostate Vehicle Control 10 2 7 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Genital System Prostate 8000 PPM 10 22 110 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 10 92 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 21 101 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 21 102 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 21 103 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 21 104 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 21 105 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 22 106 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 22 107 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 22 108 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 22 109 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney Prox Con Tub 8000 PPM 10 22 110 92 1 Karyomegaly Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 62 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 63 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 64 92 1 Cytoplasmic Alteration Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 81 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 82 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 83 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 84 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 85 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 86 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 87 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 88 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 89 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 90 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 101 92 1 Cytoplasmic Alteration Moderate Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 102 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 103 92 1 Cytoplasmic Alteration Moderate Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 104 92 1 Cytoplasmic Alteration Moderate Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 105 92 1 Cytoplasmic Alteration Moderate Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 22 106 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 22 107 92 1 Cytoplasmic Alteration Moderate Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 22 108 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 22 109 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 22 110 92 1 Cytoplasmic Alteration Mild Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 1 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 2 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 3 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 4 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 5 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 10 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 6 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 7 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 8 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 2 9 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 5 21 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 5 22 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 5 23 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 5 24 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 5 25 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 6 26 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 6 28 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 6 29 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 500 PPM 9 6 30 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 10 46 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 10 47 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 10 48 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 10 49 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 10 50 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 9 41 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 9 42 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 9 43 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 9 44 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 PPM 10 9 45 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 61 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 62 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 64 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 13 65 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 14 66 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 14 67 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 14 68 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 2000 PPM 10 14 69 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 81 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 82 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 84 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 17 85 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 86 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 87 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 88 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 89 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 4000 PPM 10 18 90 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 101 92 1 Nephropathy Mild Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 102 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 103 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 104 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 21 105 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 8000 PPM 10 22 110 92 1 Nephropathy Minimal Terminal Sacrifice