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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Cyclohexanone oxime
CASRN: ="100-64-1"
Study Number: C88047
Exposure Route: DOSED WATER
TDMS Number: 8804702
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular 5000 PPM 10 101 101 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 102 102 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 103 103 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 104 104 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 105 105 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 106 106 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 107 107 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 108 108 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 110 110 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 111 111 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 114 114 93 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 118 118 93 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 120 120 93 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver 10000 PPM 10 112 112 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 115 115 12 1 Depletion Glycogen Marked Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 116 116 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 117 117 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 119 119 12 1 Depletion Glycogen Marked Natural Death
Alimentary System Liver 2500 PPM 10 94 94 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Alimentary System Liver Vehicle Control 10 66 66 93 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Pancreas Duct 625 PPM 1 77 77 93 1 Cyst Moderate Terminal Sacrifice
Alimentary System Salivary Glands Vehicle Control 10 70 70 93 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Alimentary System Salivary Glands 5000 PPM 10 105 105 93 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Endocrine System Parathyroid Gland Vehicle Control 10 68 68 93 1 Infiltration Cellular Mild, Lymphocyte Terminal Sacrifice
Genital System Uterus 10000 PPM 10 112 112 12 1 Atrophy Mild Moribund Sacrifice
Genital System Uterus 10000 PPM 10 116 116 12 1 Atrophy Mild Moribund Sacrifice
Genital System Uterus 10000 PPM 10 117 117 12 1 Atrophy Moderate Moribund Sacrifice
Genital System Uterus 10000 PPM 10 119 119 12 1 Atrophy Mild Natural Death
Hematopoietic System Bone Marrow 10000 PPM 10 115 115 12 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 115 115 12 1 Hemorrhage Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 64 64 93 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 66 66 93 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 5000 PPM 10 105 105 93 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 114 114 93 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 113 113 93 1 Infiltration Cellular Moderate, Lymphocyte Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric 10000 PPM 10 115 115 12 1 Atrophy Mild Moribund Sacrifice
Hematopoietic System Spleen Lymph Follic 10000 PPM 10 115 115 12 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Spleen Lymph Follic 10000 PPM 10 119 119 12 1 Depletion Cellular Marked Natural Death
Hematopoietic System Spleen Red Pulp 10000 PPM 10 112 112 12 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Spleen 1250 PPM 10 83 83 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 1250 PPM 10 85 85 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 2500 PPM 10 91 91 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 2500 PPM 10 95 95 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 2500 PPM 10 97 97 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 101 101 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 102 102 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 103 103 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 104 104 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 105 105 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 106 106 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 107 107 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 108 108 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 109 109 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 110 110 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 111 111 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 113 113 93 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 114 114 93 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 118 118 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 120 120 93 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Thymus 10000 PPM 10 112 112 12 1 Atrophy Mild Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 116 116 12 1 Atrophy Minimal Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 117 117 12 1 Atrophy Mild Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 119 119 12 1 Atrophy Moderate Natural Death
Hematopoietic System Thymus 10000 PPM 10 113 113 93 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung 10000 PPM 10 115 115 12 1 Hemorrhage Minimal Moribund Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 71 71 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 72 72 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 73 73 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 74 74 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 75 75 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 76 76 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 77 77 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 78 78 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 79 79 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 80 80 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 81 81 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 82 82 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 83 83 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 84 84 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 85 85 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 86 86 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 87 87 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 88 88 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 89 89 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 90 90 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 100 100 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 91 91 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 92 92 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 93 93 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 94 94 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 95 95 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 96 96 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 97 97 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 98 98 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 99 99 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 101 101 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 102 102 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 103 103 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 104 104 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 105 105 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 107 107 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 108 108 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 109 109 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 110 110 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 111 111 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 113 113 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 114 114 93 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 118 118 93 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 120 120 93 1 Degeneration Minimal Terminal Sacrifice
Urinary System Urinary Bladder Vehicle Control 10 67 67 93 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 110 110 93 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 10000 PPM 10 118 118 93 1 Infiltration Cellular Minimal, Lymphocyte Terminal Sacrifice
Urinary System Urinary Bladder 5000 PPM 10 103 103 93 1 Inflammation Minimal Terminal Sacrifice