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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Cyclohexanone oxime
CASRN: ="100-64-1"
Study Number: C88047
Exposure Route: DOSED WATER
TDMS Number: 8804702
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular 1250 PPM 10 22 22 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 31 31 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 32 32 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 33 33 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 34 34 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 38 38 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 39 39 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 40 40 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 41 41 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 42 42 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 43 43 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 44 44 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 45 45 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 46 46 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 47 47 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 48 48 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 49 49 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 5000 PPM 10 50 50 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 52 52 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 53 53 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 54 54 92 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 56 56 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 10000 PPM 10 59 59 92 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular Vehicle Control 10 2 2 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 625 PPM 10 15 15 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 625 PPM 10 19 19 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 625 PPM 10 20 20 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1250 PPM 10 24 24 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1250 PPM 10 27 27 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1250 PPM 10 28 28 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 1250 PPM 10 30 30 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 31 31 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 2500 PPM 10 37 37 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver 10000 PPM 10 51 51 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 55 55 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 57 57 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 58 58 12 1 Depletion Glycogen Moderate Moribund Sacrifice
Alimentary System Liver 10000 PPM 10 60 60 12 1 Depletion Glycogen Mild Moribund Sacrifice
Alimentary System Liver 625 PPM 10 11 11 92 1 Hemorrhage Minimal Terminal Sacrifice
Alimentary System Liver 625 PPM 10 18 18 92 1 Inflammation Minimal Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 2 2 92 1 Inflammation Minimal Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 52 52 92 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 53 53 92 1 Hyperplasia Mild Terminal Sacrifice
Hematopoietic System Bone Marrow 10000 PPM 10 54 54 92 1 Hyperplasia Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 2 2 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 4 4 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 7 7 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 5000 PPM 10 43 43 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 5000 PPM 10 44 44 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 10000 PPM 10 52 52 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Spleen Red Pulp 10000 PPM 10 51 51 12 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Spleen Red Pulp 10000 PPM 10 55 55 12 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Spleen Red Pulp 10000 PPM 10 58 58 12 1 Depletion Cellular Mild Moribund Sacrifice
Hematopoietic System Spleen Red Pulp 10000 PPM 10 60 60 12 1 Depletion Cellular Moderate Moribund Sacrifice
Hematopoietic System Spleen 5000 PPM 10 41 41 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 42 42 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 43 43 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 44 44 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 45 45 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 46 46 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 47 47 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 48 48 92 1 Hematopoietic Cell Proliferation Minimal Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 49 49 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 5000 PPM 10 50 50 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 52 52 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 53 53 92 1 Hematopoietic Cell Proliferation Moderate Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 54 54 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 56 56 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Spleen 10000 PPM 10 59 59 92 1 Hematopoietic Cell Proliferation Mild Terminal Sacrifice
Hematopoietic System Thymus 10000 PPM 10 55 55 12 1 Atrophy Mild Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 57 57 12 1 Atrophy Mild Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 58 58 12 1 Atrophy Mild Moribund Sacrifice
Hematopoietic System Thymus 10000 PPM 10 60 60 12 1 Atrophy Minimal Moribund Sacrifice
Hematopoietic System Thymus 5000 PPM 10 42 42 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Thymus 5000 PPM 10 46 46 92 1 Hemorrhage Minimal Terminal Sacrifice
Integumentary System Skin Hair Follicle 2500 PPM 1 34 34 92 1 Atrophy Mild Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 3 3 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 17 17 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 18 18 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 21 21 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 22 22 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 23 23 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 24 24 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 25 25 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 26 26 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 27 27 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 28 28 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 29 29 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 1250 PPM 10 30 30 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 31 31 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 32 32 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 33 33 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 34 34 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 35 35 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 36 36 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 37 37 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 38 38 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 39 39 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 2500 PPM 10 40 40 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 41 41 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 42 42 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 43 43 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 44 44 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 45 45 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 46 46 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 47 47 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 48 48 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 49 49 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 5000 PPM 10 50 50 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 52 52 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 54 54 92 1 Degeneration Mild Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 56 56 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 10000 PPM 10 59 59 92 1 Degeneration Minimal Terminal Sacrifice
Respiratory System Nose Olfactory Epi 625 PPM 10 15 15 92 1 Hemorrhage Minimal Terminal Sacrifice