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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Water disinfection byproducts (Dichloroacetic acid)
CASRN: ="79-43-6"
Study Number: C96016
Exposure Route: DOSED WATER
TDMS Number: 9601601
Sex: Female
Strain and Species: F 344/N Rats

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 1000 MG/L 10 24 117 92 1 Hepatodiaphragmatic Nodule Mild Terminal Sacrifice
Alimentary System Liver 1000 MG/L 10 24 118 92 1 Hepatodiaphragmatic Nodule Mild Terminal Sacrifice
Alimentary System Mesentery Fat Vehicle Control 1 14 66 92 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Pancreas Acinus 1000 MG/L 10 24 119 92 1 Atrophy Minimal, Focal Terminal Sacrifice
Endocrine System Thyroid Gland 1000 MG/L 10 23 112 92 1 Ectopic Thymus Minimal Terminal Sacrifice
Genital System Ovary Bilateral, Periovarn Tiss 1000 MG/L 10 23 111 92 1 Cyst Moderate Terminal Sacrifice
Genital System Ovary Vehicle Control 10 14 67 92 1 Cyst Moderate Terminal Sacrifice
Genital System Uterus Vehicle Control 10 14 67 92 1 Hydrometra Minimal Terminal Sacrifice
Genital System Uterus Vehicle Control 10 14 69 92 1 Hydrometra Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mediastinal 1000 MG/L 10 24 118 92 1 Hyperplasia Moderate, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 10 13 64 92 1 Hyperplasia Moderate, Focal, Histiocytic Terminal Sacrifice
Hematopoietic System Lymph Node Mesenteric Vehicle Control 10 13 64 92 1 Hyperplasia Moderate, Lymphoid Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 14 70 92 1 Hyperplasia Minimal, Histiocytic Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 13 63 92 1 Infiltration Cellular Mild, Mixed Cell Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 MG/L 10 24 117 92 1 Dilatation Minimal Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 14 69 92 1 Nephropathy Minimal Terminal Sacrifice
Urinary System Kidney 1000 MG/L 10 24 120 92 1 Nephropathy Minimal Terminal Sacrifice