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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Water disinfection byproducts (Dichloroacetic acid)
CASRN: ="79-43-6"
Study Number: C96016
Exposure Route: DOSED WATER
TDMS Number: 9601602
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Hepatocyte Vehicle Control 10 61 61 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 61 63 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 62 67 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 62 69 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 62 70 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 63 72 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 63 73 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 63 74 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 63 75 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 64 76 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 64 77 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 64 78 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 64 79 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 67 MG/L 10 64 80 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 65 81 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 65 82 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 65 84 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 66 86 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 66 88 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 66 89 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 66 90 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 67 91 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 67 92 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 67 94 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 68 100 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 68 96 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 68 97 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 68 98 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 68 99 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 69 101 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 69 102 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 69 103 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 69 104 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 69 105 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 70 106 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 70 107 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 70 108 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 70 109 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 70 110 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 71 111 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 71 112 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 71 113 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 71 114 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 71 115 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 72 116 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 72 117 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 72 118 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 72 119 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 72 120 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Oral Mucosa Vehicle Control 1 62 69 92 1 Hyperplasia Mild, Squamous Terminal Sacrifice
Alimentary System Oral Mucosa 1000 MG/L 2 71 114 92 1 Hyperplasia Mild, Squamous Terminal Sacrifice
Alimentary System Oral Mucosa 1000 MG/L 2 72 119 92 1 Hyperplasia Mild, Squamous Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 61 61 92 1 Accessory Adrenal Cortical Nodule Moderate Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 61 62 92 1 Accessory Adrenal Cortical Nodule Moderate Terminal Sacrifice
Genital System Uterus 1000 MG/L 10 72 117 92 1 Hyperplasia Mild, Cystic Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 61 64 92 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 1000 MG/L 10 72 119 92 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 61 61 92 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung 1000 MG/L 10 71 114 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung 1000 MG/L 10 72 120 92 1 Hemorrhage Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 MG/L 10 71 113 92 1 Dilatation Mild Terminal Sacrifice