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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Water disinfection byproducts (Dichloroacetic acid)
CASRN: ="79-43-6"
Study Number: C96016
Exposure Route: DOSED WATER
TDMS Number: 9601602
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Hepatocyte Vehicle Control 10 1 1 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 2 2 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 5 5 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 7 7 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte Vehicle Control 10 8 8 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 21 21 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 22 22 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 23 23 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 27 27 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 125 MG/L 10 30 30 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 31 31 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 32 32 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 33 33 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 34 34 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 35 35 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 250 MG/L 10 36 36 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 41 41 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 42 42 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 43 43 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 44 44 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 45 45 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 46 46 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 47 47 92 1 Vacuolization Cytoplasmic Mild Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 48 48 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 49 49 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 500 MG/L 10 50 50 92 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 51 51 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 52 52 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 53 53 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 54 54 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 55 55 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 56 56 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 57 57 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 58 58 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 59 59 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Alimentary System Liver Hepatocyte 1000 MG/L 10 60 60 92 1 Vacuolization Cytoplasmic Moderate Terminal Sacrifice
Endocrine System Adrenal Cortex 1000 MG/L 10 55 55 92 1 Accessory Adrenal Cortical Nodule Moderate Terminal Sacrifice
Endocrine System Adrenal Cortex Vehicle Control 10 6 6 92 1 Degeneration Minimal, Fatty Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 10 10 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular Vehicle Control 10 9 9 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 1000 MG/L 10 51 51 92 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 1000 MG/L 10 53 53 92 1 Hemorrhage Mild Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 1000 MG/L 10 55 55 92 1 Hemorrhage Minimal Terminal Sacrifice
Hematopoietic System Lymph Node Mandibular 1000 MG/L 10 56 56 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 2 2 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 3 3 92 1 Hemorrhage Minimal Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 6 6 92 1 Hemorrhage Mild Terminal Sacrifice
Respiratory System Lung Vehicle Control 10 7 7 92 1 Hemorrhage Moderate Terminal Sacrifice
Respiratory System Lung 1000 MG/L 10 60 60 92 1 Hemorrhage Minimal Terminal Sacrifice
Urinary System Kidney Renal Tubule 1000 MG/L 10 59 59 92 1 Casts Protein Minimal Terminal Sacrifice
Urinary System Kidney 1000 MG/L 10 54 54 92 1 Cyst Moderate Terminal Sacrifice
Urinary System Kidney Vehicle Control 10 1 1 92 1 Nephropathy Minimal Terminal Sacrifice