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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Dimethylaminopropyl chloride, hydrochloride
CASRN: ="5407-04-5"
Study Number: C96006B
Exposure Route: GAVAGE
TDMS Number: 9600605
Sex: Male
Strain and Species: F 344/N Rats

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver 6.25 MG/KG 10 4 20 93 1 Hepatodiaphragmatic Nodule Minimal Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 1 1 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 2 10 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 2 7 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 2 8 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas 100 MG/KG 10 11 52 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas 100 MG/KG 10 11 54 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas 100 MG/KG 10 12 57 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Alimentary System Pancreas 100 MG/KG 10 12 58 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Cardiovascular System Heart Myocardium 100 MG/KG 10 11 51 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Cardiovascular System Heart Myocardium 100 MG/KG 10 11 55 93 1 Infiltration Cellular Minimal, Focal, Lymphocyte Terminal Sacrifice
Hematopoietic System Lymph Node Mediastinal 25 MG/KG 1 8 40 93 1 Hyperplasia Mild Terminal Sacrifice
Respiratory System Nose Goblet Cell Vehicle Control 10 1 1 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 6.25 MG/KG 10 4 18 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 6.25 MG/KG 10 4 20 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 12.5 MG/KG 10 6 27 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 12.5 MG/KG 10 6 30 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 25 MG/KG 10 7 31 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 50 MG/KG 10 9 43 79 1 Hypertrophy Minimal Natural Death
Respiratory System Nose Goblet Cell 50 MG/KG 10 9 42 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 50 MG/KG 10 9 45 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 11 52 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 11 53 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 11 54 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 11 55 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 12 57 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 12 58 93 1 Hypertrophy Minimal Terminal Sacrifice
Respiratory System Nose Goblet Cell 100 MG/KG 10 12 59 93 1 Hypertrophy Minimal Terminal Sacrifice