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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Dipropylene glycol
CASRN: ="25265-71-8"
Study Number: C88031
Exposure Route: DOSED WATER
TDMS Number: 8803104
Sex: Female
Strain and Species: B6C3F1 Mice

Female Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Centrilobular 8.0 % 10 111 111 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 112 112 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 113 113 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 115 115 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 116 116 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 117 117 91 1 Hypertrophy Mild Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 118 118 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 119 119 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Centrilobular 8.0 % 10 120 120 91 1 Hypertrophy Minimal Terminal Sacrifice
Alimentary System Liver Hepatocyte 8.0 % 10 114 114 14 1 Necrosis Minimal Moribund Sacrifice
Alimentary System Liver Vehicle Control 10 70 70 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 8.0 % 10 112 112 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 8.0 % 10 116 116 91 1 Necrosis Minimal Terminal Sacrifice
Alimentary System Liver 8.0 % 10 120 120 91 1 Vacuolization Cytoplasmic Minimal Terminal Sacrifice
Alimentary System Pancreas Vehicle Control 10 70 70 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Salivary Glands Vehicle Control 10 62 62 91 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Salivary Glands Vehicle Control 10 67 67 91 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Salivary Glands 8.0 % 10 116 116 91 1 Inflammation Minimal, Chronic Terminal Sacrifice
Alimentary System Stomach Glandular Vehicle Control 10 61 61 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Endocrine System Adrenal Cortex Subcapsular Vehicle Control 10 61 61 91 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Subcapsular Vehicle Control 10 65 65 91 1 Hyperplasia Minimal Terminal Sacrifice
Endocrine System Adrenal Cortex Subcapsular Vehicle Control 10 67 67 91 1 Hyperplasia Minimal Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 64 64 91 1 Dilatation Mild Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 65 65 91 1 Dilatation Minimal Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 66 66 91 1 Dilatation Mild Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 67 67 91 1 Dilatation Minimal Terminal Sacrifice
Genital System Clitoral Gland Vehicle Control 10 68 68 91 1 Dilatation Minimal Terminal Sacrifice
Genital System Clitoral Gland 8.0 % 10 111 111 91 1 Dilatation Minimal Terminal Sacrifice
Genital System Clitoral Gland 8.0 % 10 112 112 91 1 Dilatation Mild Terminal Sacrifice
Genital System Clitoral Gland 8.0 % 10 115 115 91 1 Dilatation Minimal Terminal Sacrifice
Genital System Clitoral Gland 8.0 % 10 118 118 91 1 Dilatation Mild Terminal Sacrifice
Genital System Clitoral Gland 8.0 % 10 120 120 91 1 Dilatation Minimal Terminal Sacrifice
Genital System Uterus Vehicle Control 10 61 61 91 1 Hyperplasia Minimal, Cystic Terminal Sacrifice
Genital System Uterus Vehicle Control 10 62 62 91 1 Hyperplasia Minimal, Cystic Terminal Sacrifice
Genital System Uterus Vehicle Control 10 64 64 91 1 Hyperplasia Minimal, Cystic Terminal Sacrifice
Genital System Uterus Vehicle Control 10 65 65 91 1 Hyperplasia Minimal, Cystic Terminal Sacrifice
Genital System Uterus 8.0 % 10 112 112 91 1 Hyperplasia Mild, Cystic Terminal Sacrifice
Hematopoietic System Bone Marrow 8.0 % 10 114 114 14 1 Atrophy Minimal Moribund Sacrifice
Hematopoietic System Bone Marrow 8.0 % 10 114 114 14 1 Congestion Moderate Moribund Sacrifice
Hematopoietic System Lymph Node Mandibular 4.0 % 1 101 101 91 1 Hyperplasia Mild, Lymphoid Terminal Sacrifice
Hematopoietic System Spleen 8.0 % 10 114 114 14 1 Atrophy Mild Moribund Sacrifice
Integumentary System Skin Subcut Tiss Vehicle Control 10 70 70 91 1 Inflammation Mild, Chronic Active Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 62 62 91 1 Degeneration Minimal, Hyaline Terminal Sacrifice
Respiratory System Nose Olfactory Epi Vehicle Control 10 65 65 91 1 Degeneration Minimal, Hyaline Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 64 64 91 1 Degeneration Minimal, Hyaline Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 66 66 91 1 Degeneration Minimal, Hyaline Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 70 70 91 1 Degeneration Minimal, Hyaline Terminal Sacrifice
Respiratory System Nose Respirat Epith Vehicle Control 10 64 64 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Pelvis Vehicle Control 10 65 65 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Kidney Pelvis 8.0 % 10 118 118 91 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Urinary System Urinary Bladder 8.0 % 10 118 118 91 1 Inflammation Minimal, Chronic Terminal Sacrifice