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Short-Term Individual Animal Non Neoplastic Diagnosis

Study Information:

Chemical Name: Methacrylonitrile
CASRN: ="126-98-7"
Study Number: C88050
Exposure Route: GAVAGE
TDMS Number: 8805004
Sex: Male
Strain and Species: B6C3F1 Mice

Male Individual Animal Non Neoplastic Diagnoses
System Organ Site Treatment Group Number Examined Cage Number Animal Number Days on Study Lesion Found Lesion Name Lesion Qualifier Removal Reason
Alimentary System Liver Vehicle Control 10 2 2 95 1 Inflammation Minimal, Chronic Active Terminal Sacrifice
Alimentary System Liver 12 MG/KG 10 124 172 32 1 Inflammation Minimal, Chronic Active Scheduled Sacrifice
Genital System Preputial Gland 12 MG/KG 10 125 173 32 1 Inflammation Moderate, Chronic Active Scheduled Sacrifice
Genital System Preputial Gland 12 MG/KG 10 128 176 32 1 Inflammation Marked, Chronic Active Scheduled Sacrifice
Genital System Seminal Vesicle 0.75 MG/KG 1 20 20 95 1 Inflammation Marked, Chronic Active Terminal Sacrifice
Hematopoietic System Spleen 12 MG/KG 10 127 175 8 1 Depletion Cellular Moderate Natural Death
Hematopoietic System Thymus 12 MG/KG 10 127 175 8 1 Atrophy Moderate Natural Death
Musculoskeletal System Skeletal Muscle Vehicle Control 10 78 126 32 1 Inflammation Minimal, Chronic Active Scheduled Sacrifice
Respiratory System Lung 12 MG/KG 10 128 176 32 1 Inflammation Mild, Chronic Active Scheduled Sacrifice
Urinary System Kidney Vehicle Control 10 78 126 32 1 Inflammation Minimal, Chronic Active Scheduled Sacrifice
Urinary System Kidney Vehicle Control 10 81 129 32 1 Inflammation Minimal, Chronic Active Scheduled Sacrifice